resulting in corresponding activity changes in the associated P450c21 (21-hydroxylase) enzyme which ultimately leads to excessive androgen production. Other... 43 KB (4,673 words) - 17:06, 28 March 2024 |
(95% of cases)involves the gene for 21-hydroxylase, which is found on 6p21.3 as part of the HLA complex; 21-hydroxylase deficiency results from a unique... 43 KB (4,403 words) - 15:41, 30 March 2024 |
cortisol (11β,17α,21-trihydroxyprogesterone) which is formed as a metabolite from 17α-hydroxyprogesterone via 11β-hydroxylase. 21-deoxycortisol is a... 14 KB (1,448 words) - 18:29, 20 February 2024 |
11β-Hydroxyprogesterone (redirect from 21-Deoxycorticosterone) increased levels of 11β-OHP occur in 21-hydroxylase deficiency. A study in 2017 has shown that in subjects with 21-hydroxylase deficiency, serum 11β-OHP concentrations... 14 KB (1,490 words) - 00:15, 11 April 2024 |
Congenital adrenal hyperplasia due to 11β-hydroxylase deficiency is a form of congenital adrenal hyperplasia (CAH) which produces a higher than normal... 10 KB (1,022 words) - 22:55, 5 January 2024 |
hyperplasia is the most common (in various forms: 21-hydroxylase, 17α-hydroxylase, 11β-hydroxylase and 3β-hydroxysteroid dehydrogenase), lipoid CAH due... 43 KB (4,252 words) - 19:54, 2 May 2024 |
of patients with the classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency]". Arq Bras Endocrinol Metabol (in Portuguese). 52 (1): 101–8... 29 KB (2,269 words) - 02:39, 8 March 2024 |
Metyrapone (category 21-Hydroxylase inhibitors) plasma cortisol less than 220 nmol/L indicates adequate inhibition of 11β-hydroxylase. In patients with intact Hypothalamo-pituitary-adrenal axis, CRH and... 6 KB (573 words) - 02:20, 30 November 2023 |
hyperplasia is the most common (in various forms: 21-hydroxylase, 17α-hydroxylase, 11β-hydroxylase and 3β-hydroxysteroid dehydrogenase), lipoid CAH due... 39 KB (3,543 words) - 03:36, 6 April 2024 |
Tioconazole (category 21-Hydroxylase inhibitors) Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by a fungus or yeast. It is marketed under the brand names... 4 KB (242 words) - 17:31, 30 April 2024 |
common form of congenital adrenal hyperplasia is due to 21-hydroxylase deficiency. 21-hydroxylase is necessary for production of both mineralocorticoids... 49 KB (5,621 words) - 10:40, 5 March 2024 |
Auchus RJ (September 2020). "Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency". The New England Journal of Medicine. 383 (13): 1248–1261... 153 KB (14,288 words) - 03:13, 4 May 2024 |
such as in congenital adrenal hyperplasia, most commonly caused by 21-hydroxylase deficiency. Acromegaly and gigantism (growth hormone and IGF-1 excess)... 32 KB (2,913 words) - 05:09, 10 April 2024 |
Ketoconazole (category 21-Hydroxylase inhibitors) cholesterol to pregnenolone, 17α-hydroxylase and 17,20-lyase, which convert pregnenolone into androgens, and 11β-hydroxylase, which converts 11-deoxycortisol... 50 KB (4,374 words) - 18:23, 30 April 2024 |
Clotrimazole (category 21-Hydroxylase inhibitors) Clc1ccccc1C(c2ccccc2)(c3ccccc3)n4ccnc4 InChI InChI=1S/C22H17ClN2/c23-21-14-8-7-13-20(21)22(25-16-15-24-17-25,18-9-3-1-4-10-18)19-11-5-2-6-12-19/h1-17H Y... 17 KB (1,422 words) - 11:09, 27 April 2024 |
and fourth-digit lengths and congenital adrenal hyperplasia due to 21-hydroxylase deficiency". Early Human Development. 70 (1–2): 47–54. doi:10... 64 KB (7,515 words) - 06:03, 28 April 2024 |
Diazepam (category 21-Hydroxylase inhibitors) Carey Dean Moore, the first death row inmate executed in Nebraska in over 21 years. Diazepam is used as a short-term sedative and anxiolytic for cats and... 102 KB (9,983 words) - 08:37, 1 May 2024 |
hydroxylated via 17α-hydroxylase (CYP17A1) and 21-hydroxylase (CYP21A2) into 17α-hydroxyprogesterone and 11-deoxycorticosterone (21-hydroxyprogesterone)... 123 KB (11,590 words) - 09:25, 11 May 2024 |
Spironolactone (category 21-Hydroxylase inhibitors) 17α-hydroxylase, 17,20-lyase, 5α-reductase, 3β-hydroxysteroid dehydrogenase, 11β-hydroxylase, 21-hydroxylase, and aldosterone synthase (18-hydroxylase).... 186 KB (18,252 words) - 21:52, 1 April 2024 |
with congenital adrenal hyperplasia due to enzyme deficiencies like 21-hydroxylase or cytochrome P450 oxidoreductase deficiency, these pathways can activate... 79 KB (8,729 words) - 04:52, 2 May 2024 |
as a sequelae from adrenal hyperplasia (because of 21-hydroxylase deficiency or 11-beta hydroxylase deficiency, the former being more common), which includes... 32 KB (3,621 words) - 16:54, 12 April 2024 |
defective, namely 21-hydroxylase and 11β-hydroxylase, lead to a build-up of 17α-OHP. In contrast, the rare patient with 17α-hydroxylase deficiency will... 13 KB (1,059 words) - 09:02, 24 January 2024 |
Levoketoconazole (category 21-Hydroxylase inhibitors) inhibitor of the enzymes CYP11B1 (11β-hydroxylase), CYP17A1 (17α-hydroxylase/17,20-lyase), and CYP21A2 (21-hydroxylase). It inhibits glucocorticoid biosynthesis... 8 KB (432 words) - 11:08, 3 December 2023 |
Danazol (category 21-Hydroxylase inhibitors) dehydrogenase/Δ5-4 isomerase, 17α-hydroxylase, 17,20-lyase, 17β-hydroxysteroid dehydrogenase, 21-hydroxylase, and 11β-hydroxylase. It has also been found to... 46 KB (3,954 words) - 04:46, 8 April 2024 |