• Thumbnail for ADF/Cofilin family
    ADF/cofilin is a family of actin-binding proteins associated with the rapid depolymerization of actin microfilaments that give actin its characteristic...
    15 KB (1,907 words) - 02:03, 1 December 2023
  • Thumbnail for Cofilin 1
    Cofilin 1 (non-muscle; n-cofilin), also known as CFL1, is a human gene, part of the ADF/cofilin family. Cofilin is a widely distributed intracellular...
    10 KB (1,199 words) - 07:54, 3 December 2023
  • Look up ADF in Wiktionary, the free dictionary. ADF may refer to: ADF/Cofilin, a family of actin-binding proteins Alternate-day fasting, a variant of...
    2 KB (251 words) - 21:33, 28 March 2024
  • Thumbnail for Cofilin-2
    1016/S0962-8924(99)01619-0. PMID 10461190. Maciver SK, Hussey PJ (2002). "The ADF/cofilin family: actin-remodeling proteins". Genome Biol. 3 (5): reviews3007. doi:10...
    9 KB (1,116 words) - 03:32, 3 December 2023
  • (LIN-11, Isl-1, MEC-3) kinases are a family of actin-binding kinases that phosphorylate members of the ADF/cofilin family of actin binding and filament severing...
    23 KB (2,664 words) - 11:19, 4 January 2024
  • Actobindin Actolinkin Actopaxin Actophorin Acumentin (= L-plastin) Adducin ADF/Cofilin Adseverin (scinderin) Afadin AFAP-110 Affixin Aginactin AIP1 Aldolase...
    10 KB (886 words) - 06:35, 18 March 2024
  • Thumbnail for SSH2
    The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins...
    5 KB (632 words) - 11:14, 4 March 2023
  • Thumbnail for Destrin
    Destrin (category Protein families)
    gene belongs to the actin-binding proteins ADF (Actin-Depolymerizing Factor)/cofilin family. This family of proteins is responsible for enhancing the...
    4 KB (406 words) - 11:41, 23 October 2023
  • Thumbnail for SSH1
    The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins...
    7 KB (919 words) - 20:08, 27 November 2023
  • severing proteins such those in the actin depolymerizing factor (ADF)/cofilin family. The kinetic barrier that prohibits spontaneous actin polymerization...
    7 KB (843 words) - 19:30, 12 November 2023
  • Thumbnail for SSH3
    The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins...
    3 KB (376 words) - 01:39, 16 August 2023
  • Thumbnail for Cyclase-associated protein family
    mammals, CAPs appear to be involved in recycling G-actin monomers from ADF/cofilins for subsequent rounds of filament assembly. In mammals, there are two...
    12 KB (1,424 words) - 09:13, 29 March 2024
  • rearrangements. In accordance with their proposed rule, proteins like ADF, cofilin and LIMK1 are slingshot substrates. Phosphatases of Regenerating Liver...
    4 KB (533 words) - 20:19, 11 November 2023
  • Thumbnail for Tropomyosin
    observed that the actin-binding protein actin depolymerisation factor (ADF)/cofilin, a factor that promotes actin filament depolymerisation, competed with...
    51 KB (6,190 words) - 02:37, 1 January 2024
  • Thumbnail for Dendritic spine
    specifically phosphorylates and, therefore, inactivates ADF/cofilin. Inactivation of cofilin leads to increased actin polymerization and expansion of...
    48 KB (5,682 words) - 20:19, 21 January 2024
  • Thumbnail for Actin
    proteins including ADF/cofilin, which has a molecular weight of 16kDa and is coded for by a single gene, called COF1; Aip1, a cofilin cofactor that promotes...
    150 KB (17,979 words) - 12:44, 12 February 2024
  • Thumbnail for Profilin
    thymosin β4 have some functional overlaps with profilin. In contrast, ADF/cofilin has some properties that antagonize profilin action. Profilin was first...
    11 KB (1,299 words) - 02:02, 1 December 2023
  • Thumbnail for Rho-associated protein kinase
    Rho-associated protein kinase (category Protein families)
    phosphorylates and activates LIM kinase, which in turn phosphorylates ADF/cofilin, thereby inactivating its actin-depolymerization activity. This results...
    19 KB (2,168 words) - 00:36, 9 November 2023
  • Thumbnail for Gelsolin
    (S4-S6). Among the lipid-binding actin regulatory proteins, gelsolin (like cofilin) preferentially binds polyphosphoinositide (PPI). The binding sequences...
    14 KB (1,645 words) - 10:13, 4 January 2024
  • Thumbnail for Alpha-actinin-4
    An actin interface distinct from that of gelsolin domain 1 and from ADF/cofilin". Eur. J. Biochem. 268 (23): 6165–75. doi:10.1046/j.0014-2956.2001.02574...
    12 KB (1,455 words) - 04:22, 8 March 2024
  • by interfering with the binding of crosslinking proteins. The ADF/Cofilin protein family also serves to severe actin-filament networks through the weak...
    13 KB (1,572 words) - 07:19, 4 January 2024