In biochemistry, allosteric regulation (or allosteric control) is the regulation of an enzyme by binding an effector molecule at a site other than the...

allostery within single enzymes. In biochemistry, allosteric regulation (or allosteric control) is the regulation of a protein by binding an effector molecule...

In pharmacology and biochemistry, allosteric modulators are a group of substances that bind to a receptor to change that receptor's response to stimuli...

Eiki J, Nagata Y (March 2004). "Structural basis for allosteric regulation of the monomeric allosteric enzyme human glucokinase". Structure. 12 (3): 429–438...

fructose-1,6-bisphosphate (FBP), which serves as an allosteric effector for the enzyme. Allosteric regulation is the binding of an effector to a site on the...

studies have proposed and experimentally demonstrated that citrate is an allosteric regulator of malate dehydrogenase depending on the concentrations of L-malate...

aspartate (D64) and valine (V292 or V284), that are necessary in allosteric regulation; proline (P210 and P610), leucine (L453 and L473), and methionine...

pathways. Acetyl-CoA is utilised in the post-translational regulation and allosteric regulation of pyruvate dehydrogenase and carboxylase to maintain and...

most important regulatory enzymes (EC 2.7.1.11) of glycolysis. It is an allosteric enzyme made of 4 subunits and controlled by many activators and inhibitors...

Zinc is essential for enzymatic activity. The structural basis for allosteric regulation of Porphobilinogen synthase (PBGS) is modulation of a quaternary...

hyperinsulinism-hyperammonemia syndrome. Allosteric regulation: This protein may use the morpheein model of allosteric regulation. Allosteric inhibitors: Guanosine triphosphate...

importance to cellular function, they can play important roles in the allosteric regulation of enzymes. Some can be useful in measuring rates of metabolic processes...

reprogramming, cell growth, and migration.[citation needed] Allosteric regulation by metabolites. The regulation of the citric acid cycle is largely determined by...

of enzyme inhibitors. These molecules are often involved in the allosteric regulation of enzymes in the control of metabolism. An example of an enzyme...

ximelagatran) Dabigatran Thrombin demonstrates a high level of allosteric regulation. Allosterism in thrombin is regulated by the exosites 1 and 2 and...

Interconversion of morpheein forms can be a structural basis for allosteric regulation, an idea noted many years ago, and later revived. A mutation that...

PMID 15158709. Ahmad MF, Dealwis CG (2013). "The Structural Basis for the Allosteric Regulation of Ribonucleotide Reductase". Oligomerization in Health and Disease...

then reduced to BH4. PAH is proposed to use the morpheein model of allosteric regulation. Mammalian PAH exists in an equilibrium consisting of tetramers...

by metabolites such as ATP serves as negative feedback regulation of the pathway. Allosteric inhibition and activation by Protein-protein interactions...

With Jean-Pierre Changeux and François Jacob, Monod proposed a theory of allosteric transitions to explain how conformational effects could allow enzyme effectors...

the physiological implications of this phenomenon remain unclear. Allosteric regulation Haldane effect Root effect Chloride shift Bohr; Hasselbalch, Krogh...

2 similar domains). This protein may use the morpheein model of allosteric regulation. PFK is about 300 amino acids in length, and structural studies...

directly.[citation needed] This protein may use the morpheein model of allosteric regulation. At the juncture of lipid synthesis and oxidation pathways, ACC...

are regulated vary. Prokaryotic PRK's are typically subject to allosteric regulation while eukaryotic PRK's are often regulated by reversible thiol/disulfide...

to hemoglobin forming carbaminohemoglobin. CO2 is considered an Allosteric regulation as the inhibition happens not at the binding site of hemoglobin...

point of regulation in saturated straight-chain fatty acid synthesis, and is subject to both phosphorylation and allosteric regulation. Regulation by phosphorylation...

point of regulation in saturated straight-chain fatty acid synthesis, and is subject to both phosphorylation and allosteric regulation. Regulation by phosphorylation...

ability of lac repressor bound with allolactose is inhibited due to allosteric regulation, thereby genes coding for proteins involved in lactose uptake and...

It gives one explanation for cooperative binding. This model for allosteric regulation of enzymes suggests that the subunits of multimeric proteins have...

serves as regulation of activity of an enzyme by its direct product(s) or downstream metabolite(s) in the metabolic pathway (see Allosteric regulation). The...