• Thumbnail for Amyloid
    Amyloids are aggregates of proteins characterised by a fibrillar morphology of typically 7–13 nm in diameter, a β-sheet secondary structure (known as cross-β)...
    60 KB (6,514 words) - 10:39, 27 March 2024
  • Thumbnail for Amyloid beta
    Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are the main component of the amyloid plaques found in the brains of people with...
    43 KB (4,769 words) - 15:53, 8 May 2024
  • Thumbnail for Cerebral amyloid angiopathy
    Cerebral amyloid angiopathy (CAA) is a form of angiopathy in which amyloid beta peptide deposits in the walls of small to medium blood vessels of the...
    18 KB (1,768 words) - 08:24, 7 May 2024
  • Thumbnail for Amyloidosis
    Amyloidosis is a group of diseases in which abnormal proteins, known as amyloid fibrils, build up in tissue. There are several non-specific and vague signs...
    55 KB (5,432 words) - 21:07, 18 April 2024
  • Thumbnail for Amyloid plaques
    Amyloid plaques (also known as neuritic plaques, amyloid beta plaques or senile plaques) are extracellular deposits of the amyloid beta (Aβ) protein mainly...
    31 KB (3,370 words) - 05:18, 1 May 2024
  • Thumbnail for Amyloid-beta precursor protein
    Amyloid-beta precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. It functions...
    49 KB (5,525 words) - 21:03, 8 March 2024
  • Serum amyloid A (SAA) proteins are a family of apolipoproteins associated with high-density lipoprotein (HDL) in plasma. Different isoforms of SAA are...
    7 KB (742 words) - 21:46, 27 November 2023
  • Thumbnail for Amylin
    Amylin, or islet amyloid polypeptide (IAPP), is a 37-residue peptide hormone. It is co-secreted with insulin from the pancreatic β-cells in the ratio...
    33 KB (4,044 words) - 04:41, 6 May 2024
  • up amyloid in Wiktionary, the free dictionary. An amyloid is any of certain insoluble fibrous protein aggregates. Amyloid may also refer to: Amyloid (mycology)...
    494 bytes (90 words) - 11:42, 22 July 2015
  • Thumbnail for Alzheimer's disease
    progress of the protein misfolding disease is largely associated with amyloid plaques, neurofibrillary tangles, and loss of neuronal connections in the...
    178 KB (18,887 words) - 08:45, 13 May 2024
  • disease due to the accumulation of abnormally folded amyloid beta (Aβ) protein in the brain. Amyloid beta is a short peptide that is an abnormal proteolytic...
    65 KB (7,749 words) - 21:50, 25 April 2024
  • In mycology a tissue or feature is said to be amyloid if it has a positive amyloid reaction when subjected to a crude chemical test using iodine as an...
    8 KB (1,449 words) - 12:54, 22 June 2023
  • Thumbnail for Proteinopathy
    cellulose, "amyloid" actually is rich in protein. Subsequent research has shown that many different proteins can form amyloid, and that all amyloids show birefringence...
    62 KB (4,592 words) - 03:35, 12 May 2024
  • Amyloid cardiomyopathy (stiff heart syndrome) is a condition resulting in the death of part of the myocardium (heart muscle). It is associated with the...
    7 KB (529 words) - 01:15, 29 December 2023
  • Anti-amyloid drugs, also known as anti-amyloid antibodies (AAA), are a class of monoclonal antibodies developed to treat Alzheimer's disease. The first...
    8 KB (868 words) - 17:47, 10 January 2024
  • Thumbnail for Familial amyloid polyneuropathy
    Familial amyloid polyneuropathy, also called transthyretin-related hereditary amyloidosis, transthyretin amyloidosis abbreviated also as ATTR (hereditary...
    14 KB (1,486 words) - 16:53, 7 February 2024
  • Lecanemab (category Anti-amyloid monoclonal antibodies)
    infusion-related reactions, and amyloid-related imaging abnormalities, a side effect known to occur with the class of antibodies targeting amyloid. Lecanemab was granted...
    24 KB (2,044 words) - 14:01, 24 April 2024
  • tissues and organs. In AA amyloidosis, the deposited protein is serum amyloid A protein (SAA), an acute-phase protein which is normally soluble and whose...
    17 KB (1,590 words) - 20:58, 6 May 2024
  • Amyloid light-chain (AL) amyloidosis, also known as primary amyloidosis, is the most common form of systemic amyloidosis. The disease is caused when a...
    11 KB (949 words) - 04:18, 19 April 2024
  • Amyloid-related imaging abnormalities (ARIA) are abnormal differences seen in magnetic resonance imaging of the brain in patients with Alzheimer's disease...
    9 KB (780 words) - 01:16, 3 January 2024
  • Thumbnail for Serum amyloid A1
    Serum amyloid A1 (SAA1) is a protein that in humans is encoded by the SAA1 gene. SAA1 is a major acute-phase protein mainly produced by hepatocytes in...
    32 KB (4,261 words) - 03:11, 11 December 2023
  • Thumbnail for Transthyretin
    associated with amyloid diseases including wild-type transthyretin amyloidosis, hereditary transthyretin amyloidosis, familial amyloid polyneuropathy (FAP)...
    20 KB (2,382 words) - 16:13, 22 January 2024
  • Thumbnail for Amyloid purpura
    Amyloid purpura is a condition marked by bleeding under the skin (purpura) in some individuals with amyloidosis. Its cause is unknown, but coagulation...
    3 KB (260 words) - 22:58, 25 April 2022
  • Thumbnail for Serum amyloid P component
    The serum amyloid P component (SAP) is the identical serum form of the amyloid P component (AP), a 25 kDa pentameric protein first identified as the pentagonal...
    6 KB (744 words) - 11:38, 20 October 2023
  • protein has been identified as part of the enzymatic complex that cleaves amyloid-beta peptide from APP. The gene contains 14 exons, and the coding portion...
    32 KB (3,621 words) - 17:25, 4 May 2024
  • Thumbnail for Prion
    aggregates of proteins called amyloids, which accumulate in infected tissue and are associated with tissue damage and cell death. Amyloids are also associated with...
    98 KB (10,669 words) - 19:32, 13 May 2024
  • Thumbnail for Neurodegenerative disease
    presence of amyloid plaques and neurofibrillary tangles. Plaques are made up of small peptides, typically 39–43 amino acids in length, called amyloid beta (also...
    63 KB (7,018 words) - 16:29, 16 April 2024
  • The familial amyloid neuropathies (or familial amyloidotic neuropathies, neuropathic heredofamilial amyloidosis, familial amyloid polyneuropathy) are a...
    6 KB (505 words) - 14:56, 27 October 2023
  • Donanemab (category Anti-amyloid monoclonal antibodies)
    abnormal protein, amyloid beta (Aβ). Although the cause of Alzheimer's disease remains unknown, advances in understanding amyloid pathology have revealed...
    16 KB (1,807 words) - 14:15, 11 March 2024
  • Thumbnail for Cardiac amyloidosis
    amyloidosis where there is depositing of the protein amyloid in the cardiac muscle and surrounding tissues. Amyloid, a misfolded and insoluble protein, can become...
    30 KB (3,368 words) - 04:03, 12 February 2024