• Anchoring fibrils (composed largely of type VII collagen) extend from the basal lamina of epithelial cells and attach to the lamina reticularis (also...
    4 KB (385 words) - 05:11, 16 August 2023
  • Thumbnail for Collagen
    Collagen (redirect from Collagen fibrils)
    Interrupted Triple Helices) (Type XIII, XVII) Microfibril forming (Type VI) Anchoring fibrils (Type VII) The five most common types are: Type I: skin, tendon, vasculature...
    70 KB (7,740 words) - 11:00, 27 May 2024
  • Thumbnail for Dermoepidermal junction
    the anchoring filaments of hemidesmosomes; the cells of the papillary layer of the dermis are attached to the basement membrane by anchoring fibrils, which...
    2 KB (173 words) - 07:23, 8 September 2023
  • Thumbnail for Basement membrane
    connective tissue attaches to the basal lamina with collagen VII anchoring fibrils and fibrillin microfibrils. The basal lamina layer can further be...
    12 KB (1,239 words) - 22:55, 20 March 2024
  • ("BL") and those of the basement membrane ("BM") are described below: Anchoring fibrils composed of type VII collagen extend from the basal lamina into the...
    6 KB (645 words) - 02:34, 6 March 2024
  • Thumbnail for Epidermolysis bullosa dystrophica
    dimerizes to form a semicircular looping structure: the anchoring fibril. Anchoring fibrils are thought to form a structural link between the epidermal...
    12 KB (980 words) - 18:04, 29 October 2023
  • cells of the epidermis, and composed of (1) type IV collagen, (2) anchoring fibrils made of type VII collagen, and (3) dermal microfibrils. Basal lamina...
    793 bytes (88 words) - 01:32, 23 June 2017
  • Thumbnail for Hemidesmosome
    epidermolysis bullosa, the layers of the papillary dermis separate from the anchoring fibrils. This is caused by mutations in the collagen 7 gene. Desmosome Epidermolysis...
    8 KB (866 words) - 03:57, 14 April 2024
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    IK, Spurr-Michaud SJ, Tisdale AS (April 1988). "Hemidesmosomes and anchoring fibril collagen appear synchronously during development and wound healing"...
    20 KB (2,248 words) - 17:32, 2 May 2024
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    cutaneous lesions. In this case, scientists discovered insufficient anchoring fibrils in the basement membrane, which caused the skin to be more fragile...
    11 KB (1,371 words) - 22:00, 16 May 2024
  • epidermolysis bullosa caused by ultrastructural abnormalities in the anchoring fibrils. Genetic linkage of the inheritance of the disease points to the region...
    3 KB (293 words) - 21:26, 15 September 2023
  • Thumbnail for Collagen, type VII, alpha 1
    domain flanked by two non-collagenous domains, and functions as an anchoring fibril between the dermal-epidermal junction in the basement membrane. Mutations...
    20 KB (2,218 words) - 16:07, 5 April 2024
  • around age 50. It is caused by antibodies to type VII collagen within anchoring fibril structures located at the dermoepidermal junction in skin. Damaged...
    5 KB (415 words) - 15:35, 29 October 2023
  • "Epidermolysis bullosa dystrophica-recessive: a possible role of anchoring fibrils in the pathogenesis". J. Invest. Dermatol. 65 (2): 203–11. doi:10...
    14 KB (1,852 words) - 09:59, 10 March 2024
  • Thumbnail for Prion
    of amyloid fibrils. The presence of amyloid fibrils in patients with degenerative diseases has been well documented. These amyloid fibrils are seen as...
    98 KB (10,670 words) - 17:21, 1 June 2024
  • Thumbnail for Tendon
    spontaneously assemble into insoluble fibrils. A collagen molecule is about 300 nm long and 1–2 nm wide, and the diameter of the fibrils that are formed can range...
    45 KB (5,121 words) - 23:41, 29 March 2024
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    the protein components instead form a perinucleolar cap. Perichromatin fibrils are visible only under electron microscope. They are located next to the...
    87 KB (9,882 words) - 00:14, 1 June 2024
  • Thumbnail for Bone morphogenetic protein 1
    bone morphogenetic protein-1 family convert procollagen VII to mature anchoring fibril collagen". J. Biol. Chem. 277 (29): 26372–8. doi:10.1074/jbc.M203247200...
    11 KB (1,431 words) - 01:11, 10 March 2024
  • desmosomes and hemidesmosomes. They consist of fine fibrils in epithelial cells that are anchored to the cytoskeleton. They were discovered by Rudolf...
    2 KB (195 words) - 07:57, 16 February 2023
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    these fibrils are oriented depend on the chirality of the channel. On the side of the PIL with positive magnetic polarity, dextral channels have fibrils which...
    17 KB (1,877 words) - 21:47, 28 May 2024
  • Thumbnail for Tight junction protein 1
    as a scaffold protein which cross-links and anchors Tight Junction (TJ) strand proteins, which are fibril-like structures within the lipid bilayer, to...
    16 KB (2,033 words) - 19:34, 28 January 2023
  • mineralized. The collagen fibril alignment in the composite material plays a large role in the material properties. These collagen fibrils form a structure known...
    57 KB (7,033 words) - 07:27, 10 May 2024
  • Thumbnail for Actin
    form microfilaments in the cytoskeleton, and the thin filaments in muscle fibrils. It is found in essentially all eukaryotic cells, where it may be present...
    150 KB (17,979 words) - 12:44, 12 February 2024
  • Thumbnail for Agrobacterium tumefaciens
    apparently are involved in the actual synthesis of the cellulose fibrils. These fibrils also anchor the bacteria to each other, helping to form a microcolony...
    38 KB (4,336 words) - 22:36, 26 May 2024
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    rooster sperm flagellum could be splayed into as many as 11, longitudinal fibrils. About 60 years later, Grigg and Hodge in 1949 and a year later Manton...
    10 KB (1,263 words) - 03:39, 31 March 2024
  • Thumbnail for Stigmaria
    in spiral lines and consist of scalariform wall thickenings, while the fibrils are similar to those in the aerial branches. The scalariform tracheids...
    12 KB (1,246 words) - 02:49, 11 March 2024
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    specifically to other copies of the same molecule, they can oligomerize to form fibrils; this process occurs often in structural proteins that consist of globular...
    99 KB (11,210 words) - 09:31, 29 May 2024
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    WE (2016). "Delayed Emergence of Subdiffraction-Sized Mutant Huntingtin Fibrils Following Inclusion Body Formation". Q Rev Biophys. 49: e2. doi:10.1017/S0033583515000219...
    30 KB (3,255 words) - 21:36, 6 September 2023
  • is formed by the basal bodies and several other structures composed of fibrils. Their function is not fully understood. The system is studied and visualised...
    2 KB (286 words) - 11:51, 28 May 2024
  • strength. Type I collagen which includes collagen strands bundled into strong fibrils has a unique tri-helical structure which increases the proteins structural...
    13 KB (1,527 words) - 00:49, 3 December 2023