• Thumbnail for Antisense RNA
    Antisense RNA (asRNA), also referred to as antisense transcript, natural antisense transcript (NAT) or antisense oligonucleotide, is a single stranded...
    24 KB (2,995 words) - 18:15, 24 September 2023
  • bases in the RNA sequence). The other strand of the double-stranded DNA molecule is referred to as negative-sense (also negative (−) or antisense), and is...
    19 KB (2,444 words) - 17:30, 3 December 2023
  • Thumbnail for Antibiotic
    liposomes. The antisense RNA then hybridizes with the bacterial mRNA and blocks its translation into the essential protein. Antisense RNA-based treatment...
    153 KB (14,468 words) - 17:14, 28 April 2024
  • promoter by an antisense RNA called CopA. CopA interacts with its RNA target in the RepA mRNA and forms a kissing complex and then a RNA-RNA duplex. The...
    9 KB (1,235 words) - 09:54, 8 October 2021
  • reported. Antisense oligonucleotides (ASO) are single strands of DNA or RNA that are complementary to a chosen sequence. In the case of antisense RNA they...
    22 KB (2,572 words) - 18:37, 23 February 2024
  • Antisense therapy is a form of treatment that uses antisense oligonucleotides (ASOs) to target messenger RNA (mRNA). ASOs are capable of altering mRNA...
    23 KB (2,212 words) - 22:18, 9 November 2023
  • Thumbnail for C4 antisense RNA
    The c4 antisense RNA is a non-coding RNA used by certain phages that infect bacteria. It was initially identified in the P1 and P7 phages of E. coli....
    6 KB (654 words) - 01:39, 3 December 2023
  • those based on messenger RNA (mRNA), antisense RNA (asRNA), RNA interference (RNAi), and RNA aptamers. Of the four types, mRNA-based therapy is the only...
    76 KB (8,848 words) - 07:41, 29 April 2024
  • Thumbnail for Long non-coding RNA
    lncRNA which do not overlap protein-coding genes. Long non-coding RNAs include intergenic lincRNAs, intronic ncRNAs, and sense and antisense lncRNAs, each...
    114 KB (12,398 words) - 22:18, 26 April 2024
  • Thumbnail for RNA interference
    known as precise, efficient, stable and better than antisense therapy for gene suppression. Antisense RNA produced intracellularly by an expression vector...
    141 KB (15,437 words) - 06:13, 22 April 2024
  • Thumbnail for Salmonella enterica
    sRNAs from Salmonella Typhi were discovered. AsdA (antisense RNA of dnaA) is a cis-encoded antisense RNA of dnaA described in S. enterica serovar Typhi....
    17 KB (1,857 words) - 04:33, 26 March 2024
  • Thumbnail for DNA
    DNA (redirect from Sense and Antisense)
    sense and antisense sequences). In both prokaryotes and eukaryotes, antisense RNA sequences are produced, but the functions of these RNAs are not entirely...
    166 KB (17,845 words) - 19:31, 23 March 2024
  • Thumbnail for Non-coding RNA
    RNAs such as microRNAs, siRNAs, piRNAs, snoRNAs, snRNAs, exRNAs, scaRNAs and the long ncRNAs such as Xist and HOTAIR. The number of non-coding RNAs within...
    67 KB (7,214 words) - 06:02, 26 February 2024
  • Thumbnail for Ionis Pharmaceuticals
    Ionis Pharmaceuticals (category Antisense RNA)
    of confidence by the market in antisense technology. In 2007, Isis and Alnylam Pharmaceuticals, which focuses on RNA interference, formed a 50/50 joint...
    16 KB (1,420 words) - 10:08, 22 March 2024
  • Thumbnail for AsponA antisense RNA
    AsponA is a small asRNA transcribed antisense to the penicillin-binding protein 1A gene called ponA. It was identified by RNAseq and the expression was...
    2 KB (223 words) - 00:25, 2 December 2023
  • individual toxin molecule. Antisense RNA-type addiction modules use a regulatory strand of RNA which is at least partially "antisense" (having complementary...
    6 KB (701 words) - 17:33, 20 August 2023
  • (typically, not always) translation into a protein. The antisense strand is thus responsible for the RNA that is later translated to protein, while the sense...
    4 KB (502 words) - 12:31, 27 September 2023
  • 1073/pnas.96.7.3339. PMC 34270. PMID 10097039. Brantl S (2002). "Antisense-RNA regulation and RNA interference". Biochimica et Biophysica Acta (BBA) - Gene Structure...
    20 KB (1,022 words) - 13:20, 22 February 2024
  • Gapmers are short DNA antisense oligonucleotide structures with RNA-like segments on both sides of the sequence. These linear pieces of genetic information...
    10 KB (1,142 words) - 05:31, 14 March 2024
  • Thumbnail for VIM antisense RNA 1
    VIM antisense RNA 1 is a protein that in humans is encoded by the VIM-AS1 gene. GRCh38: Ensembl release 89: ENSG00000229124 – Ensembl, May 2017 "Human...
    440 bytes (52 words) - 11:47, 17 October 2022
  • consecutively. antisense See template strand. antisense RNA (asRNA) A single-stranded non-coding RNA molecule containing an antisense sequence that is...
    257 KB (23,339 words) - 07:14, 30 April 2024
  • EP300 antisense RNA 1 is a protein that in humans is encoded by the EP300-AS1 gene. "Human PubMed Reference:". National Center for Biotechnology Information...
    394 bytes (44 words) - 07:49, 27 March 2022
  • Thumbnail for Small interfering RNA
    interfering RNA (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of double-stranded RNA at first non-coding RNA molecules...
    55 KB (6,760 words) - 11:46, 28 April 2024
  • Thumbnail for RNA
    transfer RNA (tRNA), microRNA (miRNA), small interfering RNA (siRNA), small nucleolar RNA (snoRNAs), Piwi-interacting RNA (piRNA), tRNA-derived small RNA (tsRNA)...
    64 KB (7,522 words) - 07:46, 20 April 2024
  • Thumbnail for Iron stress repressed RNA
    Iron stress repressed RNA (IsrR) is a cis-encoded antisense RNA which regulates the expression of the photosynthetic protein isiA. IsiA expression is...
    2 KB (226 words) - 16:26, 3 September 2021
  • Thumbnail for RNA splicing
    RNA splicing is a process in molecular biology where a newly-made precursor messenger RNA (pre-mRNA) transcript is transformed into a mature messenger...
    37 KB (4,480 words) - 08:47, 24 February 2024
  • ID2 antisense RNA 1 (head to head) is a protein that in humans is encoded by the ID2-AS1 gene. "Human PubMed Reference:". National Center for Biotechnology...
    469 bytes (50 words) - 07:21, 27 March 2022
  • Thumbnail for ATP2B1 antisense RNA 1
    ATP2B1 antisense RNA 1 is a protein that in humans is encoded by the ATP2B1-AS1 gene. GRCh38: Ensembl release 89: ENSG00000271614 – Ensembl, May 2017...
    446 bytes (52 words) - 09:19, 10 March 2024
  • Thumbnail for Morpholino
    the degradation of their target RNA molecules, unlike many antisense structural types (e.g., phosphorothioates, siRNA). Instead, Morpholinos act by "steric...
    37 KB (4,376 words) - 04:22, 30 December 2023
  • Thumbnail for Mef2c antisense rna 1
    MEF2C antisense RNA 1 is a protein that in humans is encoded by the MEF2C-AS1 gene. GRCh38: Ensembl release 89: ENSG00000248309 – Ensembl, May 2017 "Human...
    393 bytes (52 words) - 09:49, 17 October 2022