Antisense therapy is a form of treatment that uses antisense oligonucleotides (ASOs) to target messenger RNA (mRNA). ASOs are capable of altering mRNA... 23 KB (2,212 words) - 22:18, 9 November 2023 |
Oligonucleotide (redirect from Oligonucleotides, antisense) properties to the oligonucleotides and make them a key element in antisense therapy. Oligonucleotides are chemically synthesized using building blocks... 23 KB (2,579 words) - 00:55, 13 May 2024 |
Sense (molecular biology) (redirect from Antisense) various cell types. Some alternative antisense structural types have been experimentally applied as antisense therapy. In the United States, the Food and... 19 KB (2,444 words) - 17:30, 3 December 2023 |
Cystic fibrosis (redirect from Gene therapy for cystic fibrosis) function would provide an alternative to traditional antibiotic therapies. Antisense therapy is being researched to treat a subset of mutations which have... 160 KB (17,980 words) - 18:08, 7 May 2024 |
Ionis Pharmaceuticals (category Antisense RNA) head of research of GlaxoSmithKline, with a goal to commercialize antisense therapy. In 1992, the company received its first approval by the Food and... 16 KB (1,420 words) - 04:42, 11 May 2024 |
Pelacarsen (category Antisense RNA) Pelacarsen is an antisense therapy that is designed to reduce Lipoprotein(a) concentrations in people with high levels of the lipoprotein and who are... 2 KB (195 words) - 20:44, 5 January 2024 |
RNA interference (redirect from RNAi therapy) known as precise, efficient, stable and better than antisense therapy for gene suppression. Antisense RNA produced intracellularly by an expression vector... 141 KB (15,445 words) - 08:44, 6 May 2024 |
Olpasiran (category Antisense RNA) Olpasiran (AMG890) is an experimental antisense therapy designed to lower the level of lipoprotein(a), which is believed to be a causal factor in the... 2 KB (183 words) - 01:20, 17 January 2024 |
Synthetic antisense RNA has also found widespread use in gene knockdown studies, and in practical applications such as antisense therapy. anucleate (of... 266 KB (24,231 words) - 05:26, 12 May 2024 |
reactions, nausea, headache, fatigue, and fever Antisense therapy Oligonucleotide synthesis Antisense RNA therapeutics Crooke, Stanley T.; Baker, Brenda... 10 KB (1,142 words) - 05:31, 14 March 2024 |
NeuGene Antisense. Since morpholino oligomers can form sequence-specific double-stranded complexes with RNA they are suitable use in antisense therapy. In... 16 KB (1,480 words) - 13:21, 22 March 2024 |
Eteplirsen (category Antisense RNA) be used to treat about 14% of DMD cases. Eteplirsen is a form of antisense therapy. Eteplirsen was developed by Steve Wilton, Sue Fletcher and colleagues... 21 KB (1,457 words) - 13:26, 25 April 2024 |
exons to be skipped could be used to treat up to 50% of DMD patients. Antisense therapy Wahl M (1 October 2011). "Exon Skipping in DMD: What Is It and Whom... 10 KB (1,190 words) - 17:51, 16 January 2024 |
a professor at Case Western Reserve University, used CRISPR and antisense therapy in a mouse model of Pelizaeus–Merzbacher with success. In 2022 Case... 13 KB (1,183 words) - 03:06, 8 March 2024 |
address the root cause are currently available including gene therapy (Elevidys), and antisense drugs (Ataluren, Eteplirsen etc.). Other medications used... 65 KB (6,468 words) - 14:04, 15 April 2024 |
Antibiotic (redirect from Antibiotic therapy) as immunoglobulin therapy, and experimental biology-based approaches such as phage therapy, fecal microbiota transplants, antisense RNA-based treatments... 154 KB (14,470 words) - 01:32, 6 May 2024 |
Antiviral drug (redirect from Antiviral therapy) other antisense antivirals are in development. An antisense structural type that has proven especially valuable in research is morpholino antisense. Morpholino... 57 KB (6,925 words) - 01:45, 7 January 2024 |
strand Anticodon Antigen Antimorph Antiparallel Antisense Antisense RNA Antisense strand Antisense therapy AP endonuclease AP site Apert syndrome Apoptosis... 33 KB (2,517 words) - 18:25, 11 December 2023 |
the phosphate moiety is replaced by sulfur. They are the basis of antisense therapy, e.g., the drugs fomivirsen (Vitravene), oblimersen, alicaforsen,... 11 KB (1,284 words) - 05:48, 28 April 2024 |
to target specific genetic code sequences – that is, antisense therapy, a form of gene therapy. According to Riordan, he had always wanted to use the... 77 KB (7,528 words) - 20:35, 12 May 2024 |
gene editing of the astrocytes. A phase III clinical trial of an antisense therapy, sponsored by Ionis Pharmaceuticals, began in 2021. A bone marrow... 14 KB (1,455 words) - 06:33, 15 April 2024 |
calmodulin and dopamine receptors, and as pharmacological agents for antisense therapy in brain and other tissue. Weiss was born in The Bronx in 1937 and... 26 KB (3,164 words) - 05:14, 3 August 2023 |
Growth hormone therapy refers to the use of growth hormone (GH) as a prescription medication—it is one form of hormone therapy. Growth hormone is a peptide... 38 KB (4,777 words) - 14:22, 22 February 2024 |