• Thumbnail for Apoptosis
    Apoptosis (from Ancient Greek: ἀπόπτωσις, romanized: apóptōsis, lit. 'falling off') is a form of programmed cell death that occurs in multicellular organisms...
    91 KB (10,628 words) - 15:07, 21 April 2024
  • play an integral role in apoptosis. Some of these inhibitors include the Bcl-2 family, viral inhibitor crmA, and IAP's. Apoptosis, or programmed cell death...
    12 KB (1,524 words) - 16:45, 11 December 2023
  • mitochondrial pathway to apoptosis and illuminated whole new avenues of research on inflammatory diseases, cancer, and apoptosis in general. By 1998, research...
    12 KB (1,599 words) - 14:09, 24 August 2023
  • Apoptosis inhibitor of macrophage (AIM) is a protein produced by macrophages that regulates immune responses and inflammation. It plays a crucial role...
    13 KB (1,268 words) - 13:51, 26 March 2024
  • Thumbnail for Necrosis
    components. In contrast, apoptosis is a naturally occurring programmed and targeted cause of cellular death. While apoptosis often provides beneficial...
    27 KB (3,100 words) - 20:44, 17 February 2024
  • Thumbnail for Fas ligand
    other hallmarks of apoptosis. Some reports have suggested that the extrinsic Fas pathway is sufficient to induce complete apoptosis in certain cell types...
    21 KB (2,581 words) - 06:51, 29 April 2024
  • Thumbnail for PAWR
    PRKC apoptosis WT1 regulator protein, or Prostate apoptosis response-4, is a tumor-suppressor protein coded for in the human by the PAWR gene, that induces...
    11 KB (1,352 words) - 07:38, 9 December 2023
  • Programmed cell death (category Apoptosis)
    hypothesized that necroptosis can serve as a cell-death backup to apoptosis when the apoptosis signaling is blocked by endogenous or exogenous factors such...
    53 KB (6,348 words) - 09:40, 28 April 2024
  • Thumbnail for Cell death
    of "apoptosis" such as endonuclease activation can be spuriously induced without engaging a genetic cascade, however, presumably true apoptosis and programmed...
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  • Thumbnail for Bcl-2 family
    proteins consists of members that either promote or inhibit apoptosis, and control apoptosis by governing mitochondrial outer membrane permeabilization...
    16 KB (2,160 words) - 15:56, 7 April 2024
  • REVIEW: Apoptosis - Allegaeon". Distorted Sound. Retrieved April 23, 2019. Gill, Kim (April 17, 2019). "ALBUM REVIEW: Allegaeon - Apoptosis". Ghost Cult...
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  • Thumbnail for CFLAR
    CASP8 and FADD-like apoptosis regulator is a protein that in humans is encoded by the CFLAR gene. Also called c-FLIP (FLICE-like inhibitory protein)....
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  • Thumbnail for Apoptosis-inducing factor
    Apoptosis inducing factor is involved in initiating a caspase-independent pathway of apoptosis (positive intrinsic regulator of apoptosis) by causing...
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  • Thumbnail for Fas receptor
    that leads to programmed cell death (apoptosis) if it binds its ligand, Fas ligand (FasL). It is one of two apoptosis pathways, the other being the mitochondrial...
    23 KB (2,675 words) - 19:25, 12 November 2023
  • Thumbnail for Karyorrhexis
    as a result of either programmed cell death (apoptosis), cellular senescence, or necrosis. In apoptosis, the cleavage of DNA is done by Ca2+ and Mg2+...
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  • Thumbnail for Cytochrome c
    protect themselves from apoptosis by blocking the release of cytochrome c using Bcl-xL. Another way that cells can control apoptosis is by phosphorylation...
    32 KB (3,788 words) - 01:24, 27 January 2024
  • Thumbnail for Necroptosis
    cell death via apoptosis. The discovery of necroptosis showed that cells can execute necrosis in a programmed fashion and that apoptosis is not always...
    14 KB (1,667 words) - 20:15, 23 April 2024
  • Thumbnail for TRAIL
    TNF-related apoptosis-inducing ligand (TRAIL), is a protein functioning as a ligand that induces the process of cell death called apoptosis. TRAIL is a...
    11 KB (1,335 words) - 11:31, 25 August 2023
  • Thumbnail for Phosphatidylserine
    plays a key role in cell cycle signaling, specifically in relation to apoptosis. It is a key pathway for viruses to enter cells via apoptotic mimicry...
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  • Thumbnail for Inhibitor of apoptosis domain
    The inhibitor of apoptosis domain -- also known as IAP repeat, Baculovirus Inhibitor of apoptosis protein Repeat, or BIR -- is a structural motif found...
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  • Thumbnail for Apoptosis regulator BAX
    Apoptosis Apoptosome Bcl-2 BH3 interacting domain death agonist (BID) Caspases Cytochrome c Noxa Mitochondrion p53 upregulated modulator of apoptosis...
    18 KB (2,108 words) - 13:17, 21 December 2023
  • UV-induced apoptosis UV-induced apoptosis is an adequate (physiological) reaction of a cell damaged by UV radiation (UVR) in a sufficiently large (lethal)...
    16 KB (2,340 words) - 21:01, 27 November 2023
  • Thumbnail for The Hallmarks of Cancer
    occur, thus apoptosis cannot activate. They may also have defects in the downstream signaling itself, or the proteins involved in apoptosis, each of which...
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  • Thumbnail for Philadelphia chromosome
    to DNA damage and promotes apoptosis in normal cells. The BCR-ABL fusion, in contrast, has been shown to inhibit apoptosis, but its effect on DNA binding...
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  • Thumbnail for Viral shedding
    forcing the cell to undergo apoptosis or cell suicide, release of progeny into the extracellular space is possible. However, apoptosis does not necessarily result...
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  • Thumbnail for Cell division
    will be forced to undergo apoptosis. If the DNA damage cannot be repaired, activated p53 can induce cell death by apoptosis. It can do so by activating...
    38 KB (4,250 words) - 03:38, 15 February 2024
  • Thumbnail for Bcl-2
    Bcl-2 (category Apoptosis)
    regulate cell death (apoptosis), by either inhibiting (anti-apoptotic) or inducing (pro-apoptotic) apoptosis. It was the first apoptosis regulator identified...
    39 KB (4,646 words) - 14:35, 26 January 2024
  • Thumbnail for Apoptosis-inducing factor, mitochondria-associated 3
    Smoot DT (2008). "H. pylori-induced apoptosis in human gastric cancer cells mediated via the release of apoptosis-inducing factor from mitochondria"....
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  • connections undergo apoptosis. Programmed cell death is also necessary to start the process of menstruation. That's not to say that apoptosis is a perfect process...
    16 KB (2,163 words) - 19:30, 6 April 2024
  • Thumbnail for Ceramide
    Ceramide (section Apoptosis)
    mitochondria in inducing apoptosis. However, owing to the conflicting and variable nature of studies into the role of ceramide in apoptosis, the mechanism by...
    29 KB (3,310 words) - 03:20, 2 February 2024