involve the creation of artificial APCs to prime the adaptive immune system to target malignant cells. Antigen-presenting cells fall into two categories:...

Artificial antigen presenting cells (aAPCs) are engineered platforms for T-cell activation. aAPCs are used as a new technology and approach to cancer...

microenvironment. Mesenchymal stem cell derived nanoghosts exhibit cancer targeting properties. Artificial Antigen Presenting Cells (aAPCs) are polystyrene beads...

biology, chimeric antigen receptors (CARs)—also known as chimeric immunoreceptors, chimeric T cell receptors or artificial T cell receptors—are receptor...

number of other particles can qualify as artificial cells. The terms "artificial cell" and "synthetic cell" are used in a variety of different fields...

specific cell types and cytokines to persist. Plasma cells will secrete huge quantities of antibody regardless of whether or not their cognate antigen is present...

dendritic cell.[citation needed] With the exception of non-nucleated cells (including erythrocytes), all cells are capable of presenting antigen through...

upon T cell activation, and TGF-β from any of a variety of sources, including tolerizing dendritic cells (DCs), other antigen presenting cells, or in...

by antigen-presenting cells. Co-stimulation of the B cell by activated T cell resulting in its complete activation. Proliferation of B cells with resultant...

normal cells but are activated in cancer cells or peptides containing cancer-specific mutations. Antigen-presenting cells (APCs) such as dendritic cells take...

the presence of one, both, or neither of the A and B antigens on erythrocytes (red blood cells). For human blood transfusions, it is the most important...

isolating this patient's T-cells; genetically engineering these cells to express an artificial T-cell receptor designed to bind an antigen expressed on the surface...

activates them, priming them to kill other cells that present the antigen. Dendritic cells are antigen-presenting cells (APCs) in the mammalian immune system...

transform healthy cells into cancer cells, and they act by targeting tumor suppressor proteins, such as retinoblastoma protein. The LT antigen possesses a helicase...

medical publishing, also known as red cells, erythroid cells, and rarely haematids, are the most common type of blood cell and the vertebrate's principal means...

automobile trade group of Ford, Chrysler, and General Motors Artificial antigen presenting cells Association des architectes paysagistes du Canada (Canadian...

body of worn-out cells and other debris and as antigen-presenting cells (APCs) that activate the adaptive immune system. Dendritic cells are phagocytes...

proteins. Cells were discovered by Robert Hooke in 1665, who named them after their resemblance to cells inhabited by Christian monks in a monastery. Cell theory...

where selection is inspired by the affinity of antigen–antibody interactions, reproduction is inspired by cell division, and variation is inspired by somatic...

TH type. The type of T-cell help raised is determined by the differentiated state of antigen presenting cells. Dendritic cells can differentiate to secrete...

molecules have α1, α2, and α3 proteins which are present on all nucleated cells (excluding red blood cells). In humans, the β2 microglobulin protein is encoded...

recognizing an antigen present on normal cells of the organism. This enables the T cells to eliminate cells with "foreign" or "abnormal" antigens without harming...

vaccines deliver nucleic acid that codes for an antigen into host cells, which then produce that antigen, stimulating an immune response. This category...

as a complete system, can be used to create these artificial cells. In the end, these synthetic cells should meet the requirements for being deemed alive...

immune response to an antigen, and the immune system reacts by producing T cells and antibodies. The B memory cells remember the antigen so that if the body...

favorable biophysical properties have been engineered to generate artificial families of Antigen Binding Proteins (AgBP), capable of specific binding to different...

Human-leukocyte-antigen class II molecules present in B cells in the endoplasmic reticulum and are degraded. In contrast, EBV from epithelial cells are rich...

production of antigen specific immunoglobulin E (IgE). IgE then binds to IgE receptors on the surface of mast cells. Then, mast cells release histamine...

cells to differentiate (turn into) cells that function similarly to beta cells, which are in an islet cell in charge of producing insulin. Artificial...

Artificial intelligence in healthcare is the application of artificial intelligence (AI) to copy human cognition in the analysis, presentation, and understanding...