• Thumbnail for Basic helix–loop–helix
    A basic helixloophelix (bHLH) is a protein structural motif that characterizes one of the largest families of dimerizing transcription factors. The word...
    14 KB (1,402 words) - 02:37, 3 December 2023
  • Thumbnail for Basic helix-loop-helix ARNT-like protein 1
    Basic helix-loop-helix ARNT-like protein 1 or aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL), or brain and muscle ARNT-like 1 is...
    48 KB (5,635 words) - 04:46, 19 April 2024
  • Thumbnail for Helix-turn-helix
    expression. It should not be confused with the helixloophelix motif. The discovery of the helix-turn-helix motif was based on similarities between several...
    24 KB (1,415 words) - 06:24, 26 April 2024
  • Basic helix-loop-helix leucine zipper transcription factors are, as their name indicates, transcription factors containing both Basic helix-loop-helix...
    584 bytes (61 words) - 15:38, 16 April 2020
  • Thumbnail for Class A basic helix-loop-helix protein 15
    Class A basic helix-loop-helix protein 15 (bHLHa15) also known as class B basic helix-loop-helix protein 8 (bHLHb8) or muscle, intestine and stomach expression...
    4 KB (503 words) - 17:27, 26 January 2024
  • Thumbnail for BHLHE41
    "Basic helix-loop-helix family, member e41", or BHLHE41, is a gene that encodes a basic helix-loop-helix transcription factor repressor protein in various...
    27 KB (3,150 words) - 12:41, 23 April 2024
  • Thumbnail for N-Myc
    N-myc proto-oncogene protein also known as N-Myc or basic helix-loop-helix protein 37 (bHLHe37), is a protein that in humans is encoded by the MYCN gene...
    16 KB (1,978 words) - 08:36, 3 December 2023
  • Thumbnail for Myogenin
    activator encoded by the MYOG gene. Myogenin is a muscle-specific basic-helix-loop-helix (bHLH) transcription factor involved in the coordination of skeletal...
    12 KB (1,497 words) - 08:24, 26 March 2024
  • Thumbnail for EPAS1
    as oxygen concentration falls (hypoxia). The protein contains a basic helix-loop-helix protein dimerization domain as well as a domain found in signal...
    22 KB (2,679 words) - 23:01, 23 March 2024
  • Thumbnail for HIF1A
    Medicine 2019 was awarded for the discovery of HIF. HIF1A is a basic helix-loop-helix PAS domain containing protein, and is considered as the master transcriptional...
    58 KB (6,534 words) - 00:25, 18 April 2024
  • Thumbnail for Sterol regulatory element-binding protein
    are encoded by the genes SREBF1 and SREBF2. SREBPs belong to the basic-helix-loop-helix leucine zipper class of transcription factors. Unactivated SREBPs...
    18 KB (2,125 words) - 00:15, 27 December 2023
  • Thumbnail for SIM1
    Single-minded homolog 1, also known as class E basic helix-loop-helix protein 14 (bHLHe14), is a protein that in humans is encoded by the SIM1 gene. The...
    11 KB (1,379 words) - 15:39, 5 February 2024
  • Thumbnail for Twist-related protein 1
    A basic helixloophelix protein 38 (bHLHa38) is a basic helix-loop-helix transcription factor that in humans is encoded by the TWIST1 gene. Basic helix-loop-helix...
    20 KB (2,365 words) - 15:48, 21 December 2023
  • regulating transcriptional activity. These proteins usually contain the basic helix-loop-helix protein structural motif, which allows them to bind as dimers. This...
    30 KB (3,663 words) - 06:09, 22 November 2023
  • basic helix-loop-helix (bHLH) domain is found in some transcription factors and is characterized by two alpha helices (α-helixes) connected by a loop...
    21 KB (2,399 words) - 02:36, 4 January 2024
  • Thumbnail for HES1
    proteins that suppress transcription. This protein belongs to the basic helix-loop-helix (bHLH) family of transcription factors. It is a transcriptional...
    23 KB (2,892 words) - 15:13, 4 January 2024
  • Thumbnail for ID1
    protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors...
    17 KB (1,953 words) - 06:19, 24 August 2023
  • Thumbnail for Aryl hydrocarbon receptor nuclear translocator
    Bradfield CA (March 1997). "Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling...
    15 KB (1,770 words) - 15:30, 5 February 2024
  • Thumbnail for Leucine zipper
    conformation and the leucine side chains from one alpha helix interdigitate with those from the alpha helix of a second polypeptide, facilitating dimerization...
    16 KB (2,049 words) - 05:58, 25 October 2023
  • Thumbnail for MyoD
    proteins known as myogenic regulatory factors (MRFs). These bHLH (basic helix loop helix) transcription factors act sequentially in myogenic differentiation...
    27 KB (3,405 words) - 21:56, 6 November 2022
  • Thumbnail for MYCL
    protein that in humans is encoded by the MYCL1 gene. MYCL1 is a bHLH (basic helix-loop-helix) transcription factor implicated in lung cancer. MYCL1 has been...
    8 KB (1,115 words) - 19:44, 8 April 2022
  • Thumbnail for NEUROD1
    embryonic day 12 (E12). It is a member of the Neurod family of basic helix-loop-helix (bHLH) transcription factors, composed of Neurod1, Neurod2, Neurod4...
    12 KB (1,454 words) - 07:49, 8 May 2024
  • Thumbnail for Myogenesis
    myogenesis. Both MyoD and Myf5 are members of the myogenic bHLH (basic helix-loop-helix) proteins transcription factor family. Cells that make myogenic...
    23 KB (2,640 words) - 10:26, 17 January 2024
  • Helix is a database management system for the Apple Macintosh platform, created in 1983. Helix uses a graphical "programming language" to add logic to...
    12 KB (1,878 words) - 20:57, 14 December 2023
  • Thumbnail for BHLHB2
    Class E basic helix-loop-helix protein 40 is a protein that in humans is encoded by the BHLHE40 gene. DEC1 encodes a basic helix-loop-helix protein expressed...
    9 KB (1,125 words) - 16:27, 30 March 2022
  • Thumbnail for HAND1
    is encoded by the HAND1 gene. A member of the HAND subclass of basic Helix-loop-helix (bHLH) transcription factors, the Heart and neural crest-derived...
    18 KB (2,187 words) - 04:16, 1 July 2022
  • Pho regulon, a bacterial phosphate regulatory mechanism Pho4, a basic helix-loop-helix transcription factor Phos, a genus of sea snails This disambiguation...
    654 bytes (85 words) - 21:54, 4 February 2023
  • Thumbnail for Sterol regulatory element-binding protein 2
    transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix leucine zipper (bHLH-Zip) domain. Various single nucleotide polymorphisms...
    11 KB (1,450 words) - 23:13, 7 April 2022
  • Thumbnail for Barber–Say syndrome
    conserved residue of TWIST2 (twist-related protein 2). TWIST2 is a basic helix-loop-helix transcription factor that binds to E-box DNA motifs (5'-CANNTG-3')...
    5 KB (441 words) - 02:19, 25 September 2023
  • Thumbnail for TCF4
    Boddaert N, et al. (May 2007). "Mutations in TCF4, encoding a class I basic helix-loop-helix transcription factor, are responsible for Pitt-Hopkins syndrome...
    11 KB (1,152 words) - 02:44, 22 December 2023