• Bioconjugation is a chemical strategy to form a stable covalent link between two molecules, at least one of which is a biomolecule. Recent advances in...
    43 KB (4,661 words) - 07:44, 6 March 2024
  • Thumbnail for Maleimide
    (Japan). Maleimide-mediated methodologies are among the most used in bioconjugation. Due to exceptionally fast reaction rates and significantly high selectivity...
    18 KB (1,786 words) - 08:05, 29 April 2024
  • factor 1 secretion. It increases the half-life of acting agents by bioconjugation. CJC-1295 was under investigation for the treatment of lipodystrophy...
    11 KB (843 words) - 05:47, 29 November 2023
  • Thumbnail for 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide
    Ikada, Y (1995). "Mechanism of Amide Formation by Carbodiimide for Bioconjugation in Aqueous Media". Bioconjugate Chemistry. 6 (1): 123–130. doi:10.1021/bc00031a015...
    7 KB (527 words) - 16:32, 8 June 2023
  • program lies at the intersection of chemistry and biology and develops bioconjugation strategies, cytosolic delivery platforms, and rapid flow synthesis technologies...
    18 KB (1,828 words) - 22:08, 5 February 2024
  • or substrate of interest to a specific biomolecule, a process called bioconjugation. The possibility of attaching fluorophores and other reporter molecules...
    48 KB (5,477 words) - 03:30, 5 April 2024
  • Thumbnail for Phenylalanine
    is a protein-incorporated unnatural amino acid used as a tool for bioconjugation in the field of chemical biology. Ihlefeldt FS, Pettersen FB, von Bonin...
    28 KB (2,386 words) - 16:28, 30 March 2024
  • Thumbnail for ELISA
    detected by a secondary antibody that is linked to an enzyme through bioconjugation. Between each step, the plate is typically washed with a mild detergent...
    34 KB (4,393 words) - 03:08, 28 April 2024
  • Keijzer JF, Dros M, Zuilhof H, Albada B (2021-09-08). "Aptamer-Assisted Bioconjugation of Tyrosine Derivatives with hemin/G-quadruplex (hGQ) DNAzyme Nucleoapzyme...
    40 KB (4,795 words) - 07:48, 22 February 2024
  • Thumbnail for Hydrazone
    oxidative phosphorylation in molecular biology. Hydrazones are the basis of bioconjugation strategies. Hydrazone-based coupling methods are used in medical biotechnology...
    11 KB (1,169 words) - 14:34, 15 March 2024
  • is a monthly peer-reviewed scientific journal covering research in bioconjugation and the interface between man-made and biological materials. The journal...
    2 KB (115 words) - 01:34, 23 November 2023
  • Thumbnail for Bicyclononyne
    chemistry probe that enables highly efficient and completely orthogonal bioconjugation to complex macromolecules including peptides, nucleic acids and proteins...
    3 KB (208 words) - 04:28, 19 February 2024
  • Chemoselective Rapid Azo-Coupling Reaction (CRACR) for Unclickable Bioconjugation". Journal of the American Chemical Society. 139 (34): 11670–11673. doi:10...
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  • Staudinger ligation, which has been called one of the most important bioconjugation methods. Two versions of the Staudinger ligation have been developed...
    5 KB (420 words) - 18:00, 15 January 2024
  • Thumbnail for Orthogonality
    Royzen, Maksim; Fox, Joseph M. (2008). "The Tetrazine Ligation: Fast Bioconjugation based on Inverse-electron-demand Diels-Alder Reactivity". Journal of...
    15 KB (2,561 words) - 02:40, 10 April 2024
  • Thumbnail for DNA-functionalized quantum dots
    DNA or other organic materials. Another surface modification type is bioconjugation. This method uses two biomolecules which are covalently bonded to one...
    18 KB (2,269 words) - 14:51, 30 March 2024
  • reaction through the SpyTag/SpyCatcher system. Using the Tag/Catcher pair, bioconjugation can be achieved between two recombinant proteins that would otherwise...
    23 KB (2,514 words) - 03:48, 4 January 2024
  • Thumbnail for Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate
    reactive with amines and thiols respectively. SMCC is often used in bioconjugation to link proteins with other functional entities (fluorescent dyes, tracers...
    2 KB (97 words) - 22:42, 6 February 2024
  • Thumbnail for Chemical biology
    PMID 30645048. Hermanson GT (January 2013). "Chapter 3 - The Reactions of Bioconjugation". In Hermanson GT (ed.). Bioconjugate Techniques (Third ed.). Boston:...
    55 KB (6,090 words) - 01:19, 20 March 2024
  • cycloaddition has been an extremely fast and effective click reaction for bioconjugation, but it is not suitable for use in live cells due to the toxicity of...
    44 KB (5,098 words) - 05:29, 19 February 2024
  • Thumbnail for Neal Devaraj
    His research interests include artificial cells, lipid membranes, and bioconjugation. Devaraj attended college at the Massachusetts Institute of Technology...
    5 KB (441 words) - 20:27, 31 January 2024
  • Thumbnail for 3-Azidocoumarin
    3-Azidocoumarin is an organic compound that is used in the area of bioconjugation. It is a derivative of coumarin, a natural product and precursor for...
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  • Thumbnail for Allozyne
    properties and location of the 21st amino acid, allows for a variety of bioconjugation chemistries to be directed to any specific location within the protein...
    8 KB (756 words) - 21:40, 22 January 2024
  • Thumbnail for Antibody-oligonucleotide conjugate
    related to delivery and internalisation of ON therapeutics. By exploiting bioconjugation methodology several conjugates have been obtained. The first AOC was...
    19 KB (1,967 words) - 15:04, 11 December 2023
  • Thumbnail for Colloidal gold
    Parak WJ (March 2010). "Surface modification, functionalization and bioconjugation of colloidal inorganic nanoparticles". Philosophical Transactions. Series...
    85 KB (9,809 words) - 02:25, 10 April 2024
  • Thumbnail for Antibody–drug conjugate
    Yahioglu G (June 2021). "Current strategies for the discovery and bioconjugation of smaller, targetable drug conjugates tailored for solid tumor therapy"...
    40 KB (4,263 words) - 06:08, 6 April 2024
  • Coupling reaction Organometallic chemistry Ligand Bioconjugation: Transition Metal-Mediated Bioconjugation Reactions Surry, David S.; Buchwald, Stephen L...
    37 KB (3,942 words) - 04:34, 19 November 2023
  • Thumbnail for Phenylboronic acid
    inhibitors, neutron capture therapy for cancer, transmembrane transport, and bioconjugation and labeling of proteins and cell surface. 4-Nonylphenylboronic acid...
    9 KB (875 words) - 19:37, 31 May 2023
  • Thumbnail for Dielectric barrier discharge
    Containing Catechol/Quinone Groups: An Alternative to Polydopamine Bioconjugation for Biomedical Applications". Advanced Healthcare Materials. 7 (11):...
    20 KB (2,337 words) - 13:32, 21 December 2023
  • bioconjugation of an enzyme to either an antibody or antigen depending on the type of ELISA. There is much to consider in this enzyme bioconjugation such...
    47 KB (5,707 words) - 20:39, 24 August 2023