• Thumbnail for Bisphosphonate
    Bisphosphonates are a class of drugs that prevent the loss of bone density, used to treat osteoporosis and similar diseases. They are the most commonly...
    30 KB (3,429 words) - 02:49, 1 January 2024
  • Thumbnail for Medication-related osteonecrosis of the jaw
    previously known as bisphosphonate-related osteonecrosis of the jaw (BON or BRONJ) because osteonecrosis of the jaw correlating with bisphosphonate treatment was...
    46 KB (4,835 words) - 18:24, 9 December 2023
  • Thumbnail for Osteonecrosis of the jaw
    bisphosphonate therapy, which is required by some cancer treatment regimens, has been identified and defined as a pathological entity (bisphosphonate-associated...
    42 KB (5,176 words) - 19:15, 8 November 2023
  • Thumbnail for Phossy jaw
    evidence suggested the conversion of yellow phosphorus to potent amino bisphosphonates by natural chemical reactions in the human body. Yellow phosphorus...
    13 KB (1,540 words) - 16:32, 25 April 2024
  • Thumbnail for Ibandronic acid
    Ibandronic acid (category Bisphosphonates)
    Ibandronic acid is a bisphosphonate medication used in the prevention and treatment of osteoporosis and metastasis-associated skeletal fractures in people...
    8 KB (574 words) - 21:39, 20 December 2023
  • Thumbnail for C-terminal telopeptide
    between bisphosphonate use and impaired bone physiology was noted. The strong inhibition of osteoclast function precipitated by bisphosphonate therapy...
    7 KB (755 words) - 07:29, 2 January 2024
  • Thumbnail for Alendronic acid
    Alendronic acid (category Bisphosphonates)
    Alendronic acid, sold under the brand name Fosamax among others, is a bisphosphonate medication used to treat osteoporosis and Paget's disease of bone. It...
    17 KB (1,411 words) - 04:53, 3 April 2024
  • Thumbnail for Avascular necrosis
    Gaucher's disease, and Caisson disease (dysbaric osteonecrosis). Bisphosphonates are associated with osteonecrosis of the mandible (jawbone). The condition...
    26 KB (2,578 words) - 15:42, 2 May 2024
  • Thumbnail for Zoledronic acid
    Zoledronic acid (category Bisphosphonates)
    Use during pregnancy may result in harm to the baby. It is in the bisphosphonate family of medications. It works by blocking the activity of osteoclast...
    24 KB (2,095 words) - 14:34, 28 March 2024
  • Thumbnail for Complex regional pain syndrome
    evidence supports the use of bisphosphonates (either orally or via IV infusion) in the treatment of CRPS. Bisphosphonates inhibit osteoclasts: cells involved...
    62 KB (6,892 words) - 19:42, 29 April 2024
  • Thumbnail for Etidronic acid
    Etidronic acid (category Bisphosphonates)
    Etidronic acid, also known as etidronate, is a non-nitrogenous bisphosphonate used as a medication, detergent, water treatment, and cosmetic. It was patented...
    6 KB (583 words) - 11:15, 20 January 2024
  • Thumbnail for Discovery and development of bisphosphonates
    Bisphosphonates are an important class of drugs originally commercialised in the mid to late 20th century. They are used for the treatment of osteoporosis...
    19 KB (2,215 words) - 11:30, 3 December 2023
  • may include intravenous fluids, furosemide, calcitonin, intravenous bisphosphonate, in addition to treating the underlying cause. The evidence for furosemide...
    34 KB (3,298 words) - 03:10, 27 March 2024
  • Wales Bisphosphonate-associated osteonecrosis of the jaw or BRONJ, a complication of certain dental procedures for patients on bisphosphonate therapy...
    1 KB (166 words) - 13:52, 27 May 2019
  • Thumbnail for LGD-3303
    and was shown in animal studies to enhance the effectiveness of a bisphosphonate drug. Vajda EG, López FJ, Rix P, Hill R, Chen Y, Lee KJ, et al. (February...
    3 KB (203 words) - 20:12, 19 June 2022
  • Thumbnail for Risedronic acid
    Risedronic acid (category Bisphosphonates)
    Risedronic acid, often used as its sodium salt risedronate sodium, is a bisphosphonate. It slows down the cells which break down bone. It's used to treat or...
    6 KB (377 words) - 20:12, 20 December 2023
  • Thumbnail for Medronic acid
    Medronic acid (category Bisphosphonates)
    medronate), also known as methylene diphosphonate, is the smallest bisphosphonate. Its complex with radioactive technetium, 99mTc medronic acid, is used...
    2 KB (55 words) - 17:15, 13 March 2024
  • Thumbnail for Osteopenia
    heavy alcohol use). Pharmaceutical treatment for osteopenia, including bisphosphonates and other medications, may be considered in certain cases but is not...
    26 KB (2,592 words) - 02:00, 9 April 2024
  • Thumbnail for Multiple myeloma
    steroids, chemotherapy, targeted therapy, and stem cell transplant. Bisphosphonates and radiation therapy are sometimes used to reduce pain from bone lesions...
    127 KB (13,052 words) - 10:10, 8 May 2024
  • Thumbnail for Paget's disease of bone
    vary. Although there is no cure for Paget's disease, medications (bisphosphonates and calcitonin) can help control the disorder and lessen pain and other...
    40 KB (4,660 words) - 09:35, 4 April 2024
  • Thumbnail for Osteoporosis
    changes such as stopping smoking and not drinking alcohol may help. Bisphosphonate medications are useful to decrease future broken bones in those with...
    124 KB (13,908 words) - 05:10, 13 May 2024
  • Thumbnail for Osteogenesis imperfecta
    supports the use of medications of the bisphosphonate class, such as pamidronate, to increase bone density. Bisphosphonates are especially effective in children...
    150 KB (15,363 words) - 22:39, 18 April 2024
  • Thumbnail for Denosumab
    removal and is active in the body for only six months. Similarly to bisphosphonates, denosumab appears to be implicated in increasing the risk of osteonecrosis...
    25 KB (2,081 words) - 04:39, 30 April 2024
  • Thumbnail for Otosclerosis
    rationale for use of bisphosphonates". The International Tinnitus Journal. 14 (2): 92–6. PMID 19205157. "Use of bisphosphonates for otosclerosis" Archived...
    29 KB (3,314 words) - 10:06, 8 March 2024
  • Thumbnail for Osteoclast
    osteoclasts can occur in some diseases, including Paget's disease of bone and bisphosphonate toxicity. In cats, abnormal odontoclast activity can cause feline odontoclastic...
    26 KB (2,925 words) - 01:53, 25 March 2024
  • Thumbnail for Phosphonate
    herbicide Roundup), and ethephon, a widely used plant growth regulator. Bisphosphonates are popular drugs for treatment of osteoporosis. In biochemistry and...
    22 KB (2,467 words) - 04:02, 23 May 2023
  • Thumbnail for Sally Field
    Roche and GlaxoSmithKline that controversially co-promoted Boniva, a bisphosphonate treatment for osteoporosis. Field's campaign encouraged the early diagnosis...
    47 KB (4,241 words) - 23:24, 9 May 2024
  • Peritoneal Dialysis Pamidronic acid, also known as aminohydroxypropylidene bisphosphonate Antipsychotic Drugs Auditory processing disorder, difficulty in recognising...
    2 KB (244 words) - 16:42, 2 December 2023
  • Thumbnail for Pantoprazole
    mycophenolate mofetil. Additional medications that are affected include bisphosphonate derivatives, fluconazole, clopidogrel, and methotrexate. The mechanism...
    34 KB (2,703 words) - 19:44, 26 January 2024
  • in the legs (tibia, femur, fibula), followed by clavicles and spine. Bisphosphonate therapy has been suggested as a first-line therapeutic option in many...
    7 KB (703 words) - 22:37, 27 August 2023