• Thumbnail for Brincidofovir
    Brincidofovir, sold under the brand name Tembexa, is an antiviral drug used to treat smallpox. Brincidofovir is a prodrug of cidofovir. Conjugated to a...
    25 KB (2,192 words) - 04:34, 2 April 2024
  • Thumbnail for Smallpox
    military and maintained in the Strategic National Stockpile. In June 2021, brincidofovir was approved for medical use in the United States for the treatment...
    163 KB (17,672 words) - 20:19, 21 April 2024
  • Thumbnail for Progressive multifocal leukoencephalopathy
    but no proven, effective therapy is known in humans. For example, Brincidofovir (1-O-hexadecyloxypropyl-cidofovir /CMX001) available as Tembexa, suppresses...
    23 KB (2,414 words) - 19:20, 9 February 2024
  • Thumbnail for Cidofovir
    basis in the event of a bioterror incident involving smallpox cases. Brincidofovir, a cidofovir derivative with much higher activity against smallpox that...
    15 KB (1,352 words) - 23:05, 17 April 2024
  • Thumbnail for Western African Ebola virus epidemic
    Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
    320 KB (31,435 words) - 06:38, 16 April 2024
  • Thumbnail for Peter Piot
    Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
    34 KB (3,208 words) - 20:36, 17 March 2024
  • Thumbnail for Marburg virus disease
    Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
    80 KB (6,978 words) - 10:26, 19 April 2024
  • determine its safety and effectiveness in humans. Another example is brincidofovir. In June 2021, the FDA approved this drug for the treatment of smallpox...
    16 KB (1,823 words) - 20:15, 2 April 2024
  • Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
    16 KB (1,359 words) - 22:28, 23 November 2023
  • Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
    19 KB (2,308 words) - 00:44, 24 November 2023
  • Thumbnail for Ebola virus cases in the United States
    the hospital contacted Chimerix, a biotechnology company developing Brincidofovir to combat the disease. The next day, Duncan's organs were failing, and...
    117 KB (11,904 words) - 12:44, 22 February 2024
  • Thumbnail for Ebolavirus
    Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
    43 KB (4,641 words) - 17:10, 23 January 2024
  • low-resource setting, and helped to organise the trial for the drug brincidofovir during the 2014 Ebola virus outbreak. Lang started her career working...
    11 KB (1,021 words) - 07:56, 26 April 2024
  • Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
    10 KB (1,131 words) - 17:10, 22 December 2023
  • Thumbnail for Marburg virus
    Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
    51 KB (4,925 words) - 13:33, 20 November 2023
  • Thumbnail for 2023 Marburg virus disease outbreak in Equatorial Guinea
    Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
    10 KB (697 words) - 19:35, 25 March 2024
  • Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
    21 KB (2,067 words) - 22:38, 6 February 2024
  • Thumbnail for Monkeypox virus
    significant risks from tecovirimat and low certainty evidence that suggests brincidofovir may cause mild liver injury. Pain is common and may be severe; supportive...
    29 KB (3,609 words) - 01:23, 24 April 2024
  • Thumbnail for 1967 Marburg virus outbreak
    Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
    9 KB (911 words) - 17:45, 18 April 2024
  • Thumbnail for Marburg
    Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
    26 KB (2,728 words) - 15:17, 6 April 2024
  • Thumbnail for Marburgvirus
    Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
    16 KB (1,424 words) - 00:13, 6 October 2023
  • Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
    41 KB (1,579 words) - 09:25, 8 March 2024
  • Thumbnail for Mayinga N'Seka
    Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
    6 KB (588 words) - 23:02, 23 November 2023
  • Thumbnail for Reston virus
    Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
    21 KB (2,198 words) - 02:44, 14 January 2024
  • Thumbnail for Zaire ebolavirus
    Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
    48 KB (5,264 words) - 01:32, 24 February 2024
  • Thumbnail for Lamivudine
    Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
    16 KB (1,561 words) - 20:24, 17 March 2024
  • Thumbnail for Mpox
    significant risks from tecovirimat and low certainty evidence that suggests brincidofovir may cause mild liver injury. Pain is common and may be severe; supportive...
    62 KB (5,628 words) - 08:28, 25 April 2024
  • Thumbnail for Favipiravir
    Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
    34 KB (2,962 words) - 15:57, 31 March 2024
  • Thumbnail for 1976 Zaire Ebola virus outbreak
    Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
    15 KB (2,174 words) - 00:51, 3 September 2023
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    Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
    29 KB (2,686 words) - 04:47, 7 January 2024