CRISPR gene editing (pronounced /ˈkrɪspər/ "crisper") standing for "Clustered Regularly Interspaced Short Palindromic Repeats" is a genetic engineering... 151 KB (17,540 words) - 20:41, 26 April 2024 |
CRISPR-Display (CRISP-Disp) is a modification of the CRISPR/Cas9 (Clustered regularly interspaced short palindromic repeats) system for genome editing... 16 KB (2,133 words) - 12:04, 22 March 2024 |
CRISPR Therapeutics AG is a Swiss–American biotechnology company headquartered in Zug, Switzerland. It was one of the first companies formed to utilize... 11 KB (918 words) - 14:13, 19 April 2024 |
Cas9 (redirect from CRISPR/Cas9) Cas9 (CRISPR associated protein 9, formerly called Cas5, Csn1, or Csx12) is a 160 kilodalton protein which plays a vital role in the immunological defense... 43 KB (5,610 words) - 04:07, 28 November 2023 |
CRISPR activation (CRISPRa) is a type of CRISPR tool that uses modified versions of CRISPR effectors without endonuclease activity, with added transcriptional... 21 KB (2,672 words) - 22:49, 25 April 2024 |
He Jiankui affair (redirect from CRISPR baby) standard in vitro fertilisation services and in addition, use of CRISPR gene editing (CRISPR/Cas9), a technology for modifying DNA. The embryos' genomes were... 103 KB (11,552 words) - 15:17, 30 April 2024 |
Genome-wide CRISPR-Cas9 knockout screens aim to elucidate the relationship between genotype and phenotype by ablating gene expression on a genome-wide... 55 KB (6,164 words) - 23:47, 3 December 2023 |
(gRNAs) for use with the CRISPR/Cas gene editing system. The CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR associated nucleases)... 15 KB (1,247 words) - 03:26, 3 December 2023 |
CRISPR-associated transposons or CASTs are mobile genetic elements (MGEs) that have evolved to make use of minimal CRISPR systems for RNA-guided transposition... 14 KB (1,710 words) - 21:39, 19 March 2024 |
diagnostic tests using CRISPR-Cas12a and CRISPR-based therapies using its proprietary ultra-small CRISPR systems. Several CRISPR-Cas systems identified... 7 KB (685 words) - 06:53, 23 April 2024 |
Francisco Mojica (section The discovery of CRISPR) CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats). These were later developed into the first widespread genome editing tool, CRISPR-Cas9... 20 KB (1,955 words) - 15:49, 15 October 2023 |
thereby preventing the CRISPR locus from being targeted and destroyed by the CRISPR-associated nuclease. In a bacterial genome, CRISPR loci contain "spacers"... 12 KB (1,421 words) - 00:22, 14 December 2022 |
Designer baby (section CRISPR/Cas9) homology directed repair. The CRISPR/Cas9 system (CRISPR – Clustered Regularly Interspaced Short Palindromic Repeats, Cas9 – CRISPR-associated protein 9) is... 71 KB (8,212 words) - 19:07, 25 March 2024 |
Genome editing (section CRISPR) meganucleases—were selected by Nature Methods as the 2011 Method of the Year. The CRISPR-Cas system was selected by Science as 2015 Breakthrough of the Year. As... 78 KB (9,341 words) - 20:34, 24 April 2024 |
Cas12a (redirect from CRISPR/Cas12a) (CRISPR associated protein 12a, previously known as Cpf1) is a subtype of Cas12 proteins and an RNA-guided endonuclease that forms part of the CRISPR system... 13 KB (1,530 words) - 12:46, 22 March 2024 |
Guide RNA (section CRISPR In Prokaryotes) used for gene editing. In bacteria and archaea, gRNAs are a part of the CRISPR-Cas system that serves as an adaptive immune defense that protects the organism... 30 KB (3,624 words) - 01:02, 24 April 2024 |
a nonprofit scientific research institute founded by Nobel laureate and CRISPR gene editing pioneer Jennifer Doudna and biophysicist Jonathan Weissman... 36 KB (3,288 words) - 18:54, 19 April 2024 |
Emmanuelle Charpentier (section CRISPR/Cas9) Chemistry "for the development of a method for genome editing" (through CRISPR). This was the first science Nobel Prize ever won by two women only. Born... 43 KB (3,285 words) - 08:09, 16 April 2024 |
Human Nature (2019 film) (redirect from CRISPR (film documentary)) Kirschner and Dan Rather. The film describes the gene editing process of CRISPR (an acronym for "Clustered Regularly Interspaced Short Palindromic Repeats")... 9 KB (826 words) - 03:16, 10 September 2023 |
Germline mutation (section CRISPR/Cas9 editing) initiates cellular repair processes, similar to that of CRISPR/Cas9 DNA editing. Compared to CRISPR/Cas9, the therapeutic applications of this technology... 24 KB (3,080 words) - 12:39, 4 April 2023 |
Human genetic enhancement (section CRISPR/Cas9) benefits of revolutionary tools like CRISPR are endless. For example, because it can be applied directly in the embryo, CRISPR/Cas9 reduces the time required... 95 KB (10,464 words) - 18:04, 29 April 2024 |
on pooled genetic perturbation screens. Perturb-seq combines multiplexed CRISPR mediated gene inactivations with single cell RNA sequencing to assess comprehensive... 21 KB (2,588 words) - 18:53, 19 April 2024 |
Site-directed mutagenesis (redirect from CRISPR mutagenesis) alternative to site-directed mutagenesis. Since 2013, the development of the CRISPR/Cas9 technology, based on a prokaryotic viral defense system, has also allowed... 25 KB (2,973 words) - 12:43, 23 November 2023 |