• Thumbnail for CRISPR gene editing
    CRISPR gene editing (pronounced /ˈkrɪspər/ "crisper") standing for "Clustered Regularly Interspaced Short Palindromic Repeats" is a genetic engineering...
    150 KB (17,439 words) - 13:58, 7 May 2024
  • Thumbnail for CRISPR
    together with CRISPR sequences form the basis of a technology known as CRISPR-Cas9 that can be used to edit genes within the organisms. This editing process...
    150 KB (16,256 words) - 04:12, 7 May 2024
  • Thumbnail for He Jiankui affair
    addition, use of CRISPR gene editing (CRISPR/Cas9), a technology for modifying DNA. The embryos' genomes were edited to remove the CCR5 gene in an attempt...
    103 KB (11,553 words) - 19:09, 1 May 2024
  • Switzerland. It was one of the first companies formed to utilize the CRISPR gene editing platform to develop medicines for the treatment of various rare and...
    11 KB (918 words) - 14:13, 19 April 2024
  • Thumbnail for Genome editing
    regulations that anyone manipulating the human genome by gene-editing techniques, like CRISPR, would be held responsible for any related adverse consequences...
    78 KB (9,341 words) - 20:34, 24 April 2024
  • (gRNAs) for use with the CRISPR/Cas gene editing system. The CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR associated nucleases)...
    15 KB (1,247 words) - 03:26, 3 December 2023
  • Thumbnail for Jennifer Doudna
    1964) is an American biochemist who has done pioneering work in CRISPR gene editing, and made other fundamental contributions in biochemistry and genetics...
    68 KB (5,863 words) - 16:23, 27 April 2024
  • Thumbnail for Gene therapy
    study of a CRISPR-based in vivo human gene editing therapy, where the editing takes place inside the human body. The first injection of the CRISPR-Cas System...
    172 KB (17,769 words) - 04:04, 1 April 2024
  • regularly interspaced short palindromic repeats) system for genome editing. The CRISPR/Cas9 system uses a short guide RNA (sgRNA) sequence to direct a Streptococcus...
    16 KB (2,133 words) - 12:04, 22 March 2024
  • Thumbnail for Gene drive
    genome edits that would affect the germline, including those related to CRISPR-Cas9 technologies, but supported continued basic research and gene editing that...
    46 KB (5,024 words) - 05:12, 1 April 2024
  • CRISPR activation (CRISPRa) is a type of CRISPR tool that uses modified versions of CRISPR effectors without endonuclease activity, with added transcriptional...
    21 KB (2,672 words) - 22:49, 25 April 2024
  • Thumbnail for Gene targeting
    more newly developed gene-editing techniques of prime editing and base editing, based on CRISPR-Cas methods, are alternatives to gene targeting, which can...
    39 KB (4,385 words) - 10:05, 20 February 2024
  • Thumbnail for Insert (molecular biology)
    cycle. CRISPR gene editing based on Clustered regularly interspaced short palindromic repeats (CRISPR) -Cas9 is an enzyme that uses the gene sequences...
    11 KB (1,360 words) - 02:06, 3 December 2023
  • Editas Medicine (category Gene therapy)
    company which is developing therapies for rare diseases based on CRISPR gene editing technology. Editas headquarters is located in Cambridge, Massachusetts...
    15 KB (1,222 words) - 13:09, 13 April 2024
  • material in an organism's DNA to obtain desired results. Examples of gene editing are CRISPR, zinc finger nuclease, transcription activator-like effector nuclease...
    2 KB (317 words) - 13:27, 27 September 2023
  • Thumbnail for CRISPR interference
    CRISPR interference (CRISPRi) is a genetic perturbation technique that allows for sequence-specific repression of gene expression in prokaryotic and eukaryotic...
    24 KB (2,898 words) - 12:08, 22 March 2024
  • Thumbnail for Cas9
    Cas9 (redirect from CRISPR/Cas9)
    Biology portal Technology portal DCas9 activation system CRISPR CRISPR gene editing Genome editing Zinc finger nuclease Transcription activator-like effector...
    43 KB (5,610 words) - 21:17, 2 May 2024
  • enables highly precise editing of disease-causing genes directly within specific target tissues. Intellia's ex vivo programs use CRISPR to create the therapy...
    18 KB (1,607 words) - 14:47, 3 May 2024
  • nonprofit scientific research institute founded by Nobel laureate and CRISPR gene editing pioneer Jennifer Doudna and biophysicist Jonathan Weissman. The institute...
    36 KB (3,288 words) - 18:54, 19 April 2024
  • unlike them, is permanent. It works via base editing, a form of CRISPR gene editing. It is one of the first gene therapies that could be beneficial to a wider...
    3 KB (339 words) - 15:35, 4 May 2024
  • Thumbnail for LEAPER gene editing
    than the CRISPR gene editing technique. Initial studies have claimed that editing efficiencies of up to 80%. As opposed to DNA gene editing techniques...
    7 KB (783 words) - 12:15, 22 February 2024
  • Thumbnail for Human genetic enhancement
    Phenotypic Impacts of CRISPR-Cas9 Editing in Mice Targeting the Tyr Gene: In a comprehensive CRISPR-Cas9 study on gene editing, the Tyr gene in mice was targeted...
    95 KB (10,464 words) - 18:04, 29 April 2024
  • Guide RNA (category Genome editing)
    double-stranded DNA and thereby can be used for gene editing. In bacteria and archaea, gRNAs are a part of the CRISPR-Cas system that serves as an adaptive immune...
    30 KB (3,624 words) - 01:02, 24 April 2024
  • winner of the 2020 Nobel Prize in Chemistry for her work on the CRISPR system of gene editing. On March 22, 2021, Isaacson appeared on The Late Show with...
    4 KB (301 words) - 11:21, 16 January 2024
  • Boustead, Elliot Kirschner and Dan Rather. The film describes the gene editing process of CRISPR (an acronym for "Clustered Regularly Interspaced Short Palindromic...
    9 KB (826 words) - 03:16, 10 September 2023
  • methodologies similar to precursor genome editing technologies, including CRISPR/Cas9 and base editors. Prime editing has been used on some animal models of...
    26 KB (3,056 words) - 20:02, 27 April 2024
  • small clinical trial of CRISPR gene editing in which a – lipid nanoparticle formulated – CRISPR (with mCas9) gene editing therapeutic is injected in...
    277 KB (24,276 words) - 14:01, 15 April 2024
  • Thumbnail for Genome-wide CRISPR-Cas9 knockout screens
    utilises the CRISPR-Cas9 gene editing system, coupled with libraries of single guide RNAs (sgRNAs), which are designed to target every gene in the genome...
    55 KB (6,164 words) - 23:47, 3 December 2023
  • the Casφ and Cas14 families of CRISPR-associated enzymes, have demonstrated potential for therapeutic genome editing in in vivo settings. The company...
    7 KB (685 words) - 06:53, 23 April 2024
  • Thumbnail for Designer baby
    Designer baby (category Genome editing)
    Editing with CRISPRs, TALENs and ZFNs". Biocompare. "What are genome editing and CRISPR/Cas9?". Genetics Home Reference. NIH. "CRISPR Guide". AddGene...
    71 KB (8,212 words) - 19:07, 25 March 2024