Azithromycin (section Drugs metabolized by CYP3A4) pancytopenia, and organ failure. CYP3A4 is an enzyme that metabolizes many drugs in the liver. Some drugs can inhibit CYP3A4, which means they reduce its... 58 KB (5,259 words) - 22:28, 26 April 2024 |
Omeprazole (category CYP3A4 inhibitors) possible because omeprazole is an inhibitor of the enzymes CYP2C19 and CYP3A4. Clopidogrel is an inactive prodrug that partially depends on CYP2C19 for... 42 KB (3,794 words) - 12:37, 9 April 2024 |
Bellergal (section CYP3A4 inhibition) serious drug interactions due to strong CYP3A4 inhibition by ergotamine. Ergotamine is a vasoconstrictive CYP3A4 substrate. Bellergal was widely used during... 9 KB (936 words) - 14:59, 4 April 2024 |
cells. The substance is metabolised by the liver enzyme CYP3A4. In a study, the strong CYP3A4 inhibitor ketoconazole increased the maximal blood plasma... 15 KB (1,415 words) - 13:41, 16 April 2024 |
Tofisopam (category CYP3A4 inhibitors) schizophrenia. Tofisopam has been shown to act as an inhibitor of the liver enzyme CYP3A4, and some researches suspect that this could cause dangerous drug interactions... 9 KB (733 words) - 06:09, 9 February 2024 |
Cilostazol (category CYP3A4 inhibitors) Cilostazol is metabolized by CYP3A4 and CYP2C19, two isoenzymes of the cytochrome P450 system. Drugs that inhibit CYP3A4, such as itraconazole, erythromycin... 9 KB (689 words) - 06:23, 24 January 2023 |
the liver by the cytochrome P450 enzyme CYP3A4. When administered concomitantly with drugs that inhibit CYP3A4, such as ketoconazole, the metabolism of... 16 KB (1,542 words) - 08:08, 3 March 2024 |
exclusively metabolized by CYP3A4/5, though minor contributions by CYP1A2, CYP2D6, and CYP2C8 have been reported. CYP3A4 is the major enzyme involved... 60 KB (5,539 words) - 17:08, 24 April 2024 |
is the major active metabolite of ketamine, which is formed mainly by CYP3A4. Similarly to ketamine, norketamine acts as a noncompetitive NMDA receptor... 11 KB (1,026 words) - 06:30, 7 January 2024 |
ISOZYMES". "The Life Raft Group: Long List of Inhibitors and Inducers of CYP3A4 and CYP2D6". "DRUGBANK Online: Cytochrome P-450 Enzyme Inhibitors". "MEDICATIONS... 9 KB (78 words) - 09:09, 12 November 2023 |
Ticagrelor (category CYP3A4 inhibitors) other adverse effects. Ticagrelor is a weak CYP3A4 inhibitor and is known to increase the concentrations of CYP3A4 metabolised medications; however, this interaction... 36 KB (3,499 words) - 12:17, 23 April 2024 |
P-glycoprotein (P-gp) and CYP3A4. Hence P-gp and CYP3A4 inhibitors may increase plasma levels of bosutinib. Likewise CYP3A4 inducers may reduce plasma... 10 KB (594 words) - 16:12, 1 March 2024 |