• The chiral pool is a "collection of abundant enantiopure building blocks provided by nature" used in synthesis. In other words, a chiral pool would be...
    5 KB (515 words) - 11:57, 6 September 2023
  • Thumbnail for Enantioselective synthesis
    secondary amines as chiral catalysts; these are inexpensive and environmentally friendly, as no metals are involved. Chiral pool synthesis is one of the simplest...
    41 KB (4,726 words) - 05:21, 27 May 2024
  • Thumbnail for Enantiomer
    encompassed include the use of chiral starting materials (chiral pool synthesis), the use of chiral auxiliaries and chiral catalysts, and the application...
    24 KB (2,627 words) - 04:20, 22 July 2024
  • Thumbnail for Asymmetric induction
    The starting material is often derived from chiral pool synthesis. In relayed asymmetric induction the chiral information is introduced in a separate step...
    29 KB (3,675 words) - 16:03, 18 September 2024
  • racemic mixture. Asymmetric synthesis of one of the enantiomers is one means of avoiding this waste. The most common method for chiral resolution involves conversion...
    7 KB (896 words) - 02:15, 5 April 2024
  • Thumbnail for Amino acid
    low-cost feedstocks used in chiral pool synthesis as enantiomerically pure building blocks. Amino acids are used in the synthesis of some cosmetics. The chelating...
    98 KB (10,141 words) - 04:18, 2 September 2024
  • Thumbnail for Sagopilone
    form of yamaguchi macrolactonization. Block A is synthesised in a chiral pool synthesis with stable intermediate products. Therefore, large scale production...
    15 KB (1,996 words) - 16:22, 29 August 2024
  • Thumbnail for Chirality (chemistry)
    distinguishing chiral compounds. Chirality (electromagnetism) Chirality (mathematics) Chirality (physics) Enantiopure drug Enantioselective synthesis Handedness...
    31 KB (3,629 words) - 15:21, 4 August 2024
  • rearrangement Cheletropic reaction Chichibabin pyridine synthesis Chichibabin reaction Chiral pool synthesis Chugaev elimination Ciamician–Dennstedt rearrangement...
    38 KB (3,423 words) - 21:05, 20 August 2024
  • Thumbnail for Galantamine total synthesis
    derivative of tartaric acid as a chiral resolving agent. In 1977 Koga obtained both enantiomers via a chiral pool synthesis starting from L-tyrosine and in...
    15 KB (1,662 words) - 02:08, 18 September 2024
  • Thumbnail for Dihydrolevoglucosenone
    dihydrolevoglucosenone is produced as a single enantiomer, it can be used for chiral pool synthesis. For instance, oxidation with peroxy acids such as peroxyacetic...
    15 KB (1,403 words) - 14:22, 1 February 2024
  • Thumbnail for Jiadifenolide
    core of the molecule. Two further syntheses, a chiral-pool approach from (+)-pulegone and a racemic synthesis relying on a samarium diiodide–mediated reductive...
    5 KB (416 words) - 22:43, 1 June 2023
  • Thumbnail for Β-Glucosidase
    "2.8 Chiral Pool Synthesis: Chiral Pool Syntheses Starting from Carbohydrates". In Yamamoto H, Carreira EM (eds.). In Comprehensive Chirality. pp. 207–239...
    12 KB (1,299 words) - 13:39, 23 August 2024
  • Thumbnail for Potassium peroxymonosulfate
    0209. Frohn, Michael; Shi, Yian (2000). "Chiral Ketone-Catalyzed Asymmetric Epoxidation of Olefins". Synthesis. 2000 (14): 1979–2000. doi:10.1055/s-2000-8715...
    8 KB (664 words) - 15:52, 29 February 2024
  • used as a ligand for transition-metal catalysed asymmetric synthesis. BINOL has axial chirality and the two enantiomers can be readily separated and are...
    9 KB (753 words) - 22:34, 5 August 2024
  • this promise. Chemistry portal Chiral auxiliaries Chiral pool synthesis Chiral resolution Enantioselective synthesis Fiaud, J.C.; Kagan, H.B. (1988)...
    57 KB (6,914 words) - 13:54, 30 July 2024
  • Thumbnail for Chiraphos
    using cheaply available enantiopure starting materials is known as chiral pool synthesis. The diol is tosylated and then the ditosylate is treated with lithium...
    4 KB (179 words) - 12:40, 6 May 2021
  • The split and pool (split-mix) synthesis is a method in combinatorial chemistry that can be used to prepare combinatorial compound libraries. It is a stepwise...
    27 KB (3,913 words) - 07:14, 19 May 2024
  • Thumbnail for Steroid
    Steroid (redirect from Steroid synthesis)
    to progesterone. The letters α and β denote absolute stereochemistry at chiral centers—a specific nomenclature distinct from the R/S convention of organic...
    83 KB (8,473 words) - 21:34, 16 September 2024
  • Thumbnail for Oseltamivir total synthesis
    to oseltamivir that do not involve the use of (−)-shikimic acid as a chiral pool starting material, such as a Diels-Alder route involving furan and ethyl...
    20 KB (2,309 words) - 12:58, 25 October 2023
  • Thumbnail for Atorvastatin
    atorvastatin relied on a chiral pool approach, where the stereochemistry of the first alcohol functional group was carried into the synthesis—through the choice...
    99 KB (9,417 words) - 01:25, 7 September 2024
  • total synthesis of racemic ovalicin in 1985 followed by two asymmetric syntheses reported in 1994 by Samadi and Corey which featured a chiral pool strategy...
    28 KB (3,396 words) - 00:48, 2 August 2024
  • actual synthesis, based upon various calculations and criteria (see ADME, computational chemistry, and QSAR). Combinatorial split-mix (split and pool) synthesis...
    48 KB (6,510 words) - 15:49, 6 September 2024
  • Wood, and Arnold L. Rheingold (2004) "Synthesis and Structural Characterization of Trivalent Amino Acid Derived Chiral Phosphorus Compounds". J. Org. Chem...
    21 KB (2,006 words) - 08:55, 18 September 2024
  • Thumbnail for Liquid crystal
    AL, Gatdula E (January 2010). "Asymmetric synthesis of a highly soluble 'trimeric' analogue of the chiral nematic liquid crystal twist agent Merck S1011"...
    94 KB (11,489 words) - 13:45, 30 July 2024
  • specific binding-“recognition“ simple and inexpensive synthesis from primary amine functionalized (chiral-pool) starting materials and isothiocyanates easy to...
    19 KB (1,875 words) - 00:16, 8 June 2024
  • Thumbnail for 3-Chloromethcathinone
    these molecules are both known designer drugs. Since 3-CMC contains a chiral center, there are two enantiomers, namely (S)-3-CMC and (R)-3-CMC. The products...
    15 KB (1,659 words) - 15:44, 8 September 2024
  • Thumbnail for Mitragynine pseudoindoxyl
    synthesis of the natural product has been also accomplished using a chiral pool based strategy. This study also demonstrated structural plasticity in...
    9 KB (737 words) - 21:33, 31 August 2024
  • simply by mixing chiral aza-BH adduct, phosphine and acid. Aza-BH reactions are known in asymmetric synthesis by making use of chiral ligands. In one study...
    5 KB (473 words) - 06:49, 10 July 2024
  • In enantioselective synthesis, a non-linear effect refers to a process in which the enantiopurity of the catalyst or chiral auxiliary does not correspond...
    24 KB (3,183 words) - 07:01, 30 August 2022