The chiral pool is a "collection of abundant enantiopure building blocks provided by nature" used in synthesis. In other words, a chiral pool would be...
5 KB (515 words) - 11:57, 6 September 2023
secondary amines as chiral catalysts; these are inexpensive and environmentally friendly, as no metals are involved. Chiral pool synthesis is one of the simplest...
41 KB (4,726 words) - 05:21, 27 May 2024
Enantiomer (redirect from Chiral amplification)
encompassed include the use of chiral starting materials (chiral pool synthesis), the use of chiral auxiliaries and chiral catalysts, and the application...
24 KB (2,627 words) - 04:20, 22 July 2024
Asymmetric induction (redirect from Chiral induction)
The starting material is often derived from chiral pool synthesis. In relayed asymmetric induction the chiral information is introduced in a separate step...
29 KB (3,675 words) - 16:03, 18 September 2024
racemic mixture. Asymmetric synthesis of one of the enantiomers is one means of avoiding this waste. The most common method for chiral resolution involves conversion...
7 KB (896 words) - 02:15, 5 April 2024
Amino acid (section Chirality)
low-cost feedstocks used in chiral pool synthesis as enantiomerically pure building blocks. Amino acids are used in the synthesis of some cosmetics. The chelating...
98 KB (10,141 words) - 04:18, 2 September 2024
Sagopilone (section Synthesis)
form of yamaguchi macrolactonization. Block A is synthesised in a chiral pool synthesis with stable intermediate products. Therefore, large scale production...
15 KB (1,996 words) - 16:22, 29 August 2024
distinguishing chiral compounds. Chirality (electromagnetism) Chirality (mathematics) Chirality (physics) Enantiopure drug Enantioselective synthesis Handedness...
31 KB (3,629 words) - 15:21, 4 August 2024
rearrangement Cheletropic reaction Chichibabin pyridine synthesis Chichibabin reaction Chiral pool synthesis Chugaev elimination Ciamician–Dennstedt rearrangement...
38 KB (3,423 words) - 21:05, 20 August 2024
derivative of tartaric acid as a chiral resolving agent. In 1977 Koga obtained both enantiomers via a chiral pool synthesis starting from L-tyrosine and in...
15 KB (1,662 words) - 02:08, 18 September 2024
dihydrolevoglucosenone is produced as a single enantiomer, it can be used for chiral pool synthesis. For instance, oxidation with peroxy acids such as peroxyacetic...
15 KB (1,403 words) - 14:22, 1 February 2024
Jiadifenolide (section Chemical synthesis)
core of the molecule. Two further syntheses, a chiral-pool approach from (+)-pulegone and a racemic synthesis relying on a samarium diiodide–mediated reductive...
5 KB (416 words) - 22:43, 1 June 2023
"2.8 Chiral Pool Synthesis: Chiral Pool Syntheses Starting from Carbohydrates". In Yamamoto H, Carreira EM (eds.). In Comprehensive Chirality. pp. 207–239...
12 KB (1,299 words) - 13:39, 23 August 2024
Potassium peroxymonosulfate (redirect from Pool shock)
0209. Frohn, Michael; Shi, Yian (2000). "Chiral Ketone-Catalyzed Asymmetric Epoxidation of Olefins". Synthesis. 2000 (14): 1979–2000. doi:10.1055/s-2000-8715...
8 KB (664 words) - 15:52, 29 February 2024
used as a ligand for transition-metal catalysed asymmetric synthesis. BINOL has axial chirality and the two enantiomers can be readily separated and are...
9 KB (753 words) - 22:34, 5 August 2024
this promise. Chemistry portal Chiral auxiliaries Chiral pool synthesis Chiral resolution Enantioselective synthesis Fiaud, J.C.; Kagan, H.B. (1988)...
57 KB (6,914 words) - 13:54, 30 July 2024
using cheaply available enantiopure starting materials is known as chiral pool synthesis. The diol is tosylated and then the ditosylate is treated with lithium...
4 KB (179 words) - 12:40, 6 May 2021
The split and pool (split-mix) synthesis is a method in combinatorial chemistry that can be used to prepare combinatorial compound libraries. It is a stepwise...
27 KB (3,913 words) - 07:14, 19 May 2024
Steroid (redirect from Steroid synthesis)
to progesterone. The letters α and β denote absolute stereochemistry at chiral centers—a specific nomenclature distinct from the R/S convention of organic...
83 KB (8,473 words) - 21:34, 16 September 2024
to oseltamivir that do not involve the use of (−)-shikimic acid as a chiral pool starting material, such as a Diels-Alder route involving furan and ethyl...
20 KB (2,309 words) - 12:58, 25 October 2023
Atorvastatin (section Chemical synthesis)
atorvastatin relied on a chiral pool approach, where the stereochemistry of the first alcohol functional group was carried into the synthesis—through the choice...
99 KB (9,417 words) - 01:25, 7 September 2024
Rubottom oxidation (section Applications in synthesis)
total synthesis of racemic ovalicin in 1985 followed by two asymmetric syntheses reported in 1994 by Samadi and Corey which featured a chiral pool strategy...
28 KB (3,396 words) - 00:48, 2 August 2024
Combinatorial chemistry (redirect from Combinatorial synthesis)
actual synthesis, based upon various calculations and criteria (see ADME, computational chemistry, and QSAR). Combinatorial split-mix (split and pool) synthesis...
48 KB (6,510 words) - 15:49, 6 September 2024
Wood, and Arnold L. Rheingold (2004) "Synthesis and Structural Characterization of Trivalent Amino Acid Derived Chiral Phosphorus Compounds". J. Org. Chem...
21 KB (2,006 words) - 08:55, 18 September 2024
AL, Gatdula E (January 2010). "Asymmetric synthesis of a highly soluble 'trimeric' analogue of the chiral nematic liquid crystal twist agent Merck S1011"...
94 KB (11,489 words) - 13:45, 30 July 2024
specific binding-“recognition“ simple and inexpensive synthesis from primary amine functionalized (chiral-pool) starting materials and isothiocyanates easy to...
19 KB (1,875 words) - 00:16, 8 June 2024
3-Chloromethcathinone (section Synthesis)
these molecules are both known designer drugs. Since 3-CMC contains a chiral center, there are two enantiomers, namely (S)-3-CMC and (R)-3-CMC. The products...
15 KB (1,659 words) - 15:44, 8 September 2024
synthesis of the natural product has been also accomplished using a chiral pool based strategy. This study also demonstrated structural plasticity in...
9 KB (737 words) - 21:33, 31 August 2024
simply by mixing chiral aza-BH adduct, phosphine and acid. Aza-BH reactions are known in asymmetric synthesis by making use of chiral ligands. In one study...
5 KB (473 words) - 06:49, 10 July 2024
In enantioselective synthesis, a non-linear effect refers to a process in which the enantiopurity of the catalyst or chiral auxiliary does not correspond...
24 KB (3,183 words) - 07:01, 30 August 2022