Spironolactone (category Cholesterol side-chain cleavage enzyme inhibitors) weakly inhibit a broad array of steroidogenic enzymes including cholesterol side-chain cleavage enzyme, 17α-hydroxylase, 17,20-lyase, 5α-reductase, 3β-hydroxysteroid... 186 KB (18,252 words) - 21:52, 1 April 2024 |
Ketoconazole (category Cholesterol side-chain cleavage enzyme inhibitors) Specifically, ketoconazole has been shown to inhibit cholesterol side-chain cleavage enzyme, which converts cholesterol to pregnenolone, 17α-hydroxylase and 17,20-lyase... 50 KB (4,369 words) - 10:03, 6 April 2024 |
Lipoid congenital adrenal hyperplasia (redirect from Cholesterol side-chain-cleavage enzyme deficiency) 22-desmolase, but now identified as cytochrome P450scc (cholesterol side chain cleavage enzyme). However, few cases of lipoid CAH due to a mutation and... 20 KB (2,367 words) - 10:40, 5 March 2024 |
Aminoglutethimide (category Cholesterol side-chain cleavage enzyme inhibitors) enzymes such as cholesterol side-chain cleavage enzyme (CYP11A1, P450scc) and aromatase (CYP19A1), thereby inhibiting the conversion of cholesterol into... 32 KB (2,828 words) - 01:55, 30 November 2023 |
Danazol (category Cholesterol side-chain cleavage enzyme inhibitors) varying extents, of a variety of steroidogenic enzymes, including cholesterol side-chain cleavage enzyme, 3β-hydroxysteroid dehydrogenase/Δ5-4 isomerase... 46 KB (3,954 words) - 04:46, 8 April 2024 |
Desmolase (category Enzymes) Examples of desmolases are: Cholesterol side-chain cleavage enzyme, also called 20,22-desmolase; converts cholesterol to pregnenolone. 17,20-Desmolase... 1 KB (148 words) - 17:32, 15 August 2023 |
HPTE (category Cholesterol side-chain cleavage enzyme inhibitors) disruptor which has estrogenic activity, and also inhibits Cholesterol side-chain cleavage enzyme (P450scc, CYP11A1) and 3α-hydroxysteroid dehydrogenase (3α-HSD)... 4 KB (254 words) - 00:17, 9 January 2023 |
toxicity caused by accumulation of desmosterol in tissues. Cholesterol side-chain cleavage enzyme (P450scc, CYP11A1) inhibitors such as aminoglutethimide... 37 KB (2,107 words) - 11:12, 27 September 2022 |
steroid hormones from cholesterol. Cholesterol ((3β)-cholest-5-en-3-ol) is hydroxylated by cholesterol side-chain cleavage enzyme (P450scc) to form... 3 KB (186 words) - 16:33, 26 April 2023 |
Levoketoconazole (category Cholesterol side-chain cleavage enzyme inhibitors) Levoketoconazole has also been found to inhibit CYP11A1 (cholesterol side-chain cleavage enzyme) and CYP51A1 (lanosterol-14α-demethylase), similarly but... 8 KB (432 words) - 11:08, 3 December 2023 |
Mitotane (category Cholesterol side-chain cleavage enzyme inhibitors) inhibitor of the adrenal cortex. It acts as an inhibitor of cholesterol side-chain cleavage enzyme (P450scc, CYP11A1), and also of 11β-hydroxylase (CYP11B1)... 11 KB (813 words) - 04:40, 3 April 2024 |
steroid hormones from cholesterol. Cholesterol ((3β)-cholest-5-en-3-ol) is hydroxylated by cholesterol side-chain cleavage enzyme (P450scc) to form... 3 KB (177 words) - 05:24, 8 May 2023 |
Canrenone (category Cholesterol side-chain cleavage enzyme inhibitors) spironolactone, canrenone inhibits steroidogenic enzymes such as 11β-hydroxylase, cholesterol side-chain cleavage enzyme, 17α-hydroxylase, 17,20-lyase, and 21-hydroxylase... 14 KB (1,084 words) - 20:41, 17 December 2023 |
cytochrome P450 modulators, or inhibitors and inducers of cytochrome P450 enzymes. In alphabetical order. List of steroid metabolism modulators Includes... 9 KB (78 words) - 09:09, 12 November 2023 |
Etomidate (category Cholesterol side-chain cleavage enzyme inhibitors) synthesis in the adrenal cortex by reversibly inhibiting 11β-hydroxylase, an enzyme important in adrenal steroid production; it leads to primary adrenal suppression... 31 KB (3,311 words) - 17:56, 21 March 2024 |
testosterone Cholesterol side-chain cleavage enzyme inhibitors (P450SCC/CYP11A1 inhibitors): inhibit the synthesis of pregnenolone from cholesterol, thereby... 3 KB (266 words) - 18:40, 1 December 2023 |
Congenital adrenal hyperplasia (category Cholesterol and steroid metabolism disorders) CYP17A1 (17α-hydroxylase/17,20-lyase), CYP11A1 (P450scc; cholesterol side-chain cleavage enzyme), STAR (steroidogenic acute regulatory protein; StAR), CYB5A... 43 KB (4,403 words) - 15:41, 30 March 2024 |
Trilostane (category Cholesterol side-chain cleavage enzyme inhibitors) intended for breeding Side effects of trilostane in conjunction with a corticosteroid in humans include gastrointestinal side effects like gastritis... 24 KB (1,897 words) - 03:30, 20 March 2024 |
estrogens Cholesterol side-chain cleavage enzyme inhibitors (P450SCC/CYP11A1 inhibitors): inhibit the synthesis of pregnenolone from cholesterol, thereby... 2 KB (183 words) - 11:06, 27 September 2022 |
include: Cholesterol side-chain cleavage enzyme inhibitors (P450SCC/CYP11A1 inhibitors): inhibit the synthesis of pregnenolone from cholesterol, thereby... 2 KB (186 words) - 11:06, 27 September 2022 |
deficiency, 3β-hydroxysteroid dehydrogenase deficiency, and cholesterol side-chain cleavage enzyme or steroidogenic acute regulatory protein deficiency) and... 25 KB (2,798 words) - 17:49, 30 August 2023 |
cholesterol contributes to the fluidity of the cell membrane, as the molecule is in a trans conformation making all but the side chain of cholesterol... 79 KB (8,518 words) - 20:19, 27 April 2024 |