• Thumbnail for Corticosteroid 11-beta-dehydrogenase isozyme 2
    Corticosteroid 11-β-dehydrogenase isozyme 2 also known as 11-β-hydroxysteroid dehydrogenase 2 is an enzyme that in humans is encoded by the HSD11B2 gene...
    11 KB (1,085 words) - 19:55, 22 September 2023
  • Thumbnail for Cortisone
    Cortisone (category Corticosteroids)
    cortisol is inactivated to cortisone by the enzyme corticosteroid 11-beta-dehydrogenase isozyme 2. This is crucial because cortisol is a potent mineralocorticoid...
    16 KB (1,509 words) - 14:16, 24 December 2023
  • Thumbnail for Mineralocorticoid receptor
    because mineralocorticoid-responsive cells express Corticosteroid 11-beta-dehydrogenase isozyme 2, an enzyme which selectively inactivates glucocorticoids...
    14 KB (1,628 words) - 10:26, 5 January 2024
  • genome encodes two distinct HSD-11β isozymes (HSD-11β Type 1 and HSD-11β Type 2) on distinct genes. The dehydrogenase activity of a HSD-11β converts a...
    17 KB (1,900 words) - 21:43, 18 March 2024
  • PMID 13295221. Schultz RM, Groman EV, Engel LL (June 1977). "3(17)beta-Hydroxysteroid dehydrogenase of Pseudomonas testosteroni. A convenient purification and...
    31 KB (2,641 words) - 21:34, 4 May 2024
  • Thumbnail for 11α-Hydroxyprogesterone
    11α-Hydroxyprogesterone (category 11β-Hydroxysteroid dehydrogenase inhibitors)
    1997). "Human 11 beta-hydroxysteroid dehydrogenase: studies on the stably transfected isoforms and localization of the type 2 isozyme within renal tissue"...
    10 KB (848 words) - 01:10, 23 July 2023
  • Thumbnail for Cortisone reductase deficiency
    produced by hexose-6-phosphate dehydrogenase (H6PD). H6PD is distinct from its isozyme, glucose-6-phosphate dehydrogenase (G6PDH) in that G6PDH is a cytolytic...
    15 KB (1,506 words) - 17:59, 9 April 2023
  • Thumbnail for AKR1C3
    also known as 17β-hydroxysteroid dehydrogenase type 5 (17β-HSD5, HSD17B5) or 3α-hydroxysteroid dehydrogenase type 2 (3α-HSD2) is a steroidogenic enzyme...
    12 KB (1,526 words) - 04:06, 2 May 2024
  • Thumbnail for Finasteride
    S2CID 44363501. Azzouni F, Godoy A, Li Y, Mohler J (2012). "The 5 alpha-reductase isozyme family: a review of basic biology and their role in human diseases". Adv...
    74 KB (7,428 words) - 17:44, 10 April 2024
  • Thumbnail for Androgen backdoor pathway
    17α-diol-20-one (5α-Pdiol) via 3α-reduction by a 3α-hydroxysteroid dehydrogenase isozyme (AKR1C2 and AKR1C4) or HSD17B6, that also has 3α-reduction activity...
    79 KB (8,729 words) - 04:52, 2 May 2024