• Thumbnail for Cortisone
    Cortisone is a pregnene (21-carbon) steroid hormone. It is a naturally-occurring corticosteroid metabolite that is also used as a pharmaceutical prodrug...
    16 KB (1,509 words) - 14:16, 24 December 2023
  • Thumbnail for Cortisone acetate
    Cortisone acetate (brand names Adreson, Cortison, Cortisone, Cortisone Acetate, Cortone, Cortistab, Cortisyl, others) is a synthetic glucocorticoid corticosteroid...
    4 KB (165 words) - 09:56, 27 December 2023
  • Thumbnail for Corticosteroid
    21H 30O 5), corticosterone (C 21H 30O 4), cortisone (C 21H 28O 5) and aldosterone (C 21H 28O 5) (cortisone and aldosterone are isomers). The main corticosteroids...
    41 KB (4,133 words) - 04:03, 1 May 2024
  • Thumbnail for Prednisone
    Prednisone (redirect from Delta-cortisone)
    synthetic pregnane corticosteroid and derivative of cortisone and is also known as δ1-cortisone or 1,2-dehydrocortisone or as 17α,21-dihydroxypregna-1...
    30 KB (2,716 words) - 08:48, 9 May 2024
  • androstenedione 5β-reductase, cholestenone 5β-reductase, cortisone 5β-reductase, cortisone Δ4-5β-reductase, steroid 5β-reductase, testosterone 5β-reductase...
    5 KB (486 words) - 12:46, 26 August 2023
  • Thumbnail for Cortisone reductase deficiency
    Cortisone reductase deficiency is caused by dysregulation of the 11β-hydroxysteroid dehydrogenase type 1 enzyme (11β-HSD1), otherwise known as cortisone...
    15 KB (1,506 words) - 17:59, 9 April 2023
  • In enzymology, a cortisone alpha-reductase (EC 1.3.1.4) is an enzyme that catalyzes the chemical reaction 4,5alpha-dihydrocortisone + NADP+ ⇌ {\displaystyle...
    2 KB (148 words) - 19:02, 26 August 2023
  • Thumbnail for Philip Showalter Hench
    Prize for Physiology or Medicine in 1950 for the discovery of the hormone cortisone, and its application for the treatment of rheumatoid arthritis. The Nobel...
    9 KB (939 words) - 23:58, 27 April 2024
  • Thumbnail for Cortisol
    Cortisol (redirect from Gyno-Cortisone)
    biologically inert cortisone to biologically active cortisol 11-beta HSD2 uses the cofactor NAD+ to convert cortisol to cortisone Overall, the net effect...
    77 KB (8,516 words) - 23:51, 30 April 2024
  • or 11β-HSD) enzymes catalyze the conversion of inert 11 keto-products (cortisone) to active cortisol, or vice versa, thus regulating the access of glucocorticoids...
    17 KB (1,900 words) - 21:43, 18 March 2024
  • Thumbnail for Percy Lavon Julian
    work laid the foundation for the steroid drug industry's production of cortisone, other corticosteroids, and birth control pills. He later started his...
    57 KB (5,911 words) - 13:43, 25 April 2024
  • Thumbnail for Upjohn
    the time. Upjohn developed a process for the large scale production of cortisone. The oxygen atom at the 11 position in this steroid is an absolute requirement...
    7 KB (632 words) - 04:20, 2 March 2024
  • the 1975 Tour de France by using cortisone. In 1982, after retiring from racing, he said "I was doped with cortisone for three years and there were many...
    375 KB (39,705 words) - 01:52, 5 February 2024
  • teacher and family man whose life spins out of control when he misuses cortisone. It is based on a 1955 article by medical writer Berton Roueché in The...
    13 KB (1,555 words) - 12:19, 26 January 2024
  • Thumbnail for Adrenal gland
    blood pressure and electrolyte balance. The glucocorticoids cortisol and cortisone are synthesized in the zona fasciculata; their functions include the regulation...
    49 KB (5,621 words) - 10:40, 5 March 2024
  • Thumbnail for Pregnene
    A pregnene is an alkene derivative of a pregnane. An example is cortisone. Cortisone Ethisterone Spironolactone Pregnenes at the U.S. National Library...
    366 bytes (33 words) - 02:15, 8 December 2016
  • its effects in an interview: "At first it distorted my hands. Then the cortisone I had to take made my cheeks fat. At 8, I lost movement in my neck. When...
    8 KB (861 words) - 04:25, 31 March 2024
  • Thumbnail for Tadeusz Reichstein
    Medicine laureate (1950), which was awarded for his work on the isolation of cortisone. Reichstein was born into a Polish-Jewish family at Włocławek, Russian...
    7 KB (644 words) - 07:48, 1 October 2023
  • assisted by a radiographer. Contrast medium, a local anaesthetic and cortisone are injected into the joint. Then up to 40ml of sterile saline solution...
    2 KB (215 words) - 05:06, 3 December 2023
  • second polymorph was found with more suitable compressive properties. Cortisone acetate exists in at least five different polymorphs, four of which are...
    46 KB (4,920 words) - 16:41, 7 April 2024
  • Thumbnail for Diosgenin
    of such hydrolysis, diosgenin is used for the commercial synthesis of cortisone, pregnenolone, progesterone, and other steroid products. It is present...
    5 KB (340 words) - 13:27, 15 January 2024
  • Thumbnail for Edward Calvin Kendall
    used to treat rheumatoid arthritis. The compound was eventually named cortisone. In 1950, Kendall and Hench, along with Swiss chemist Tadeus Reichstein...
    9 KB (750 words) - 22:23, 27 April 2024
  • Thumbnail for Hydrocortisone
    Hydrocortisone is metabolized by 11β-hydroxysteroid dehydrogenases (11β-HSDs) into cortisone, an inactive metabolite. It is additionally 5α-, 5β-, and 3α-reduced into...
    29 KB (2,269 words) - 02:39, 8 March 2024
  • Thumbnail for Polyarteritis nodosa
    nodosa after experiencing excruciating chest pain and is treated with cortisone. Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology:...
    17 KB (1,662 words) - 17:29, 14 August 2023
  • While serving as a research scientist at Merck & Co., Inc., synthesized cortisone. He was born in Champaign, Illinois. His father was Lew Sarett, a renowned...
    4 KB (304 words) - 17:33, 22 December 2023
  • to all steroids in that group. Hydrocortisone, hydrocortisone acetate, cortisone acetate, tixocortol pivalate, prednisolone, methylprednisolone, and prednisone...
    13 KB (1,364 words) - 17:48, 2 December 2023
  • Thumbnail for Floyd Mayweather Jr.
    dating back to 2008. Additionally Pacquiao's camp had not requested a cortisone injection, which is allowed by the US Anti-Doping Agency, but rather a...
    285 KB (24,908 words) - 18:01, 6 May 2024
  • Thumbnail for Avascular necrosis
    substances. During that tour, Landis was allowed cortisone shots to help manage his ailment, despite cortisone also being a banned substance in professional...
    26 KB (2,578 words) - 15:42, 2 May 2024
  • Thumbnail for Brown recluse spider
    depending on pain scores, an anti-inflammatory agent (e.g. naproxen, cortisone), and an antispasmodic (e.g. cyclobenzaprine, diazepam), for a few days...
    39 KB (4,516 words) - 03:47, 24 April 2024
  • Thumbnail for Aldosterone
    with intracellular adrenal steroid receptors and converts cortisol into cortisone, a relatively inactive metabolite with little affinity for the MR. Liquorice...
    32 KB (3,377 words) - 13:20, 24 January 2024