• In genomics, DNADNA hybridization is a molecular biology technique that measures the degree of genetic similarity between DNA sequences. It is used to...
    14 KB (1,537 words) - 06:59, 22 February 2024
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    pool of DNA whose sequence is to be determined is fluorescently labeled and hybridized to an array containing known sequences. Strong hybridization signals...
    129 KB (14,413 words) - 04:34, 7 April 2024
  • to hybridize with RNA spike-ins. The degree of hybridization between the spike-ins and the control probes is used to normalize the hybridization measurements...
    54 KB (5,427 words) - 14:19, 26 April 2024
  • DNA can hybridize with the more common B-DNA. These A-B intermediate forms adopt the sugar pucker properties and/or the base conformation of both DNA...
    12 KB (1,229 words) - 01:59, 5 October 2023
  • Thumbnail for DNA computing
    Tianqi; Garg, Sudhanshu; Reif, John (2018-01-25). "Localized DNA Hybridization Chain Reactions on DNA Origami". ACS Nano. 12 (2): 1146–1155. doi:10.1021/acsnano...
    43 KB (4,916 words) - 14:41, 5 April 2024
  • Thumbnail for DNA methylation
    Methylation Assay measures locus-specific DNA methylation using array hybridization. Bisulfite-treated DNA is hybridized to probes on "BeadChips." Single-base...
    115 KB (13,262 words) - 14:22, 26 April 2024
  • molecules to anneal or “hybridize” to each other. DNA replication and transcription of DNA into RNA both rely upon nucleotide hybridization, as do molecular...
    5 KB (564 words) - 01:25, 29 November 2023
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    Deoxyribonucleic acid (/diːˈɒksɪˌraɪboʊnjuːˌkliːɪk, -ˌkleɪ-/ ; DNA) is a polymer composed of two polynucleotide chains that coil around each other to...
    166 KB (17,845 words) - 19:31, 23 March 2024
  • Thumbnail for Complementary DNA
    complementary DNA (cDNA) is DNA that was reverse transcribed (via reverse transcriptase) from an RNA (e.g., messenger RNA or microRNA). cDNA exists in both...
    19 KB (2,275 words) - 19:34, 18 February 2024
  • Fluorescence In Situ Hybridization (FISH) technique was developed in the 1980s. The basic idea is to use a nucleic acid probe to hybridize nuclear DNA from either...
    24 KB (3,168 words) - 15:17, 9 March 2024
  • Thumbnail for DNA ligase
    extremely high hybridization stringency and ligation specificity. There are at least three different units used to measure the activity of DNA ligase: Weiss...
    23 KB (2,787 words) - 19:13, 28 January 2024
  • Thumbnail for DNA sequencer
    A DNA sequencer is a scientific instrument used to automate the DNA sequencing process. Given a sample of DNA, a DNA sequencer is used to determine the...
    37 KB (3,850 words) - 23:38, 23 March 2024
  • include RNA:DNA hybridization leading to the discovery that considerably less than 10% of the human genome was complementary to mRNA and this DNA was in the...
    41 KB (4,539 words) - 03:29, 30 April 2024
  • In molecular biology, a hybridization probe (HP) is a fragment of DNA or RNA, usually 15–10000 nucleotides long, which can be radioactively or fluorescently...
    8 KB (999 words) - 22:01, 28 March 2024
  • sites in a DNA sample generates variable lengths of DNA fragments, which are separated using gel electrophoresis. They are then hybridized with DNA probes...
    12 KB (1,498 words) - 02:31, 5 February 2024
  • Thumbnail for DNA nanotechnology
    S2CID 2064216. DNA machines: Yan H, Zhang X, Shen Z, Seeman NC (January 2002). "A robust DNA mechanical device controlled by hybridization topology". Nature...
    84 KB (9,648 words) - 04:25, 26 February 2024
  • on each end allowing for hybridization. Once the target gene has hybridized to the vector DNA, they can be joined using a DNA ligase. An alternative strategy...
    14 KB (1,699 words) - 14:24, 8 July 2023
  • Thumbnail for Eukaryotic DNA replication
    Eukaryotic DNA replication is a conserved mechanism that restricts DNA replication to once per cell cycle. Eukaryotic DNA replication of chromosomal DNA is central...
    119 KB (14,643 words) - 16:04, 26 April 2024
  • Thumbnail for Recombinant DNA
    Recombinant DNA (rDNA) molecules are DNA molecules formed by laboratory methods of genetic recombination (such as molecular cloning) that bring together...
    35 KB (3,893 words) - 18:47, 27 March 2024
  • Thumbnail for Southern blot
    permanently attach the transferred DNA to the membrane. Hybridization: After that, a hybridization probe—a single DNA fragment with a particular sequence...
    17 KB (2,310 words) - 09:53, 4 January 2024
  • genomic hybridization (CGH) is a molecular cytogenetic method for analysing copy number variations (CNVs) relative to ploidy level in the DNA of a test...
    40 KB (5,284 words) - 19:47, 28 February 2024
  • Thumbnail for Circulating tumor DNA
    tumor DNA (ctDNA) is tumor-derived fragmented DNA in the bloodstream that is not associated with cells. ctDNA should not be confused with cell-free DNA (cfDNA)...
    49 KB (5,856 words) - 05:57, 9 April 2024
  • Thumbnail for Fluorescence in situ hybridization
    microfluidic flow to increase DNA hybridization efficiency, decreasing expensive FISH probe consumption and reduce the hybridization time. MA-FISH is applied...
    40 KB (4,617 words) - 05:21, 17 December 2023
  • e., the dsDNA molecule exists as two independent strands), is referred to as having been denatured by the high temperature. Hybridization is the process...
    24 KB (2,915 words) - 15:37, 7 March 2024
  • Thumbnail for Primer (molecular biology)
    need to be chosen to uniquely select for a region of DNA, avoiding the possibility of hybridization to a similar sequence nearby. A commonly used method...
    16 KB (2,112 words) - 01:14, 11 April 2024
  • extension products from wild-type DNA and mutant DNA. Single base specificity provides advantages over hybridization-based techniques using TaqMan hydrolysis...
    49 KB (5,793 words) - 22:28, 28 March 2024
  • Thumbnail for Transcription (biology)
    of DNA into RNA. The segments of DNA transcribed into RNA molecules that can encode proteins produce messenger RNA (mRNA). Other segments of DNA are...
    58 KB (6,780 words) - 13:42, 20 April 2024
  • Thumbnail for Molecular cloning
    experimental methods in molecular biology that are used to assemble recombinant DNA molecules and to direct their replication within host organisms. The use...
    32 KB (4,016 words) - 16:47, 6 April 2024
  • Thumbnail for Nucleic acid double helix
    A-DNA and B-DNA. There is also evidence of protein-DNA complexes forming Z-DNA structures. Other conformations are possible; A-DNA, B-DNA, C-DNA, E-DNA...
    42 KB (5,016 words) - 22:06, 7 April 2024
  • maize mitochondrial genome with the help of cross-hybridization, chloroplast and mitochondrial DNA, and physical mapping of homologous regions. After...
    54 KB (6,819 words) - 11:57, 2 April 2024