DNA mismatch repair (MMR) is a system for recognizing and repairing erroneous insertion, deletion, and mis-incorporation of bases that can arise during... 35 KB (4,179 words) - 14:19, 26 April 2024 |
MLH1 (section Role in DNA mismatch repair) DNA mismatch repair protein Mlh1 or MutL protein homolog 1 is a protein that in humans is encoded by the MLH1 gene located on chromosome 3. The gene is... 28 KB (3,414 words) - 10:03, 27 March 2024 |
MSH2 (section Role in mismatch repair) DNA mismatch repair protein Msh2 also known as MutS homolog 2 or MSH2 is a protein that in humans is encoded by the MSH2 gene, which is located on chromosome... 35 KB (4,241 words) - 12:31, 19 November 2023 |
enzyme action. Nicks allow DNA strands to untwist during replication, and are also thought to play a role in the DNA mismatch repair mechanisms that fix errors... 15 KB (2,017 words) - 07:06, 28 December 2023 |
Mismatch repair cancer syndrome (MMRCS) is a cancer syndrome associated with biallelic DNA mismatch repair mutations. It is also known as Turcot syndrome... 7 KB (622 words) - 01:36, 11 March 2023 |
MSH6 (section Importance of mismatch repair) MSH6 or mutS homolog 6 is a gene that codes for DNA mismatch repair protein Msh6 in the budding yeast Saccharomyces cerevisiae. It is the homologue of... 23 KB (2,942 words) - 20:15, 5 April 2024 |
Howard Hughes Medical Institute. He is known for his research on DNA mismatch repair. Modrich received the Nobel Prize in Chemistry 2015, jointly with... 9 KB (711 words) - 08:24, 16 April 2024 |
PMS2 (redirect from Mismatch repair endonuclease pms2) is involved in DNA mismatch repair. The protein forms a heterodimer with MLH1 and this complex interacts with MSH2 bound to mismatched bases. Defects... 27 KB (3,249 words) - 19:11, 22 December 2023 |
DNA mismatch repair protein, MutS Homolog 3 (MSH3) is a human homologue of the bacterial mismatch repair protein MutS that participates in the mismatch... 17 KB (2,080 words) - 15:35, 9 January 2024 |
major deleted tumor suppressor loci. Mutations in genes employed in DNA mismatch repair (MMR) cause a high mutation rate. In tumors, such frequent subsequent... 25 KB (2,802 words) - 14:16, 3 December 2023 |
07.009. PMC 4862604. PMID 26437586. Kunkel TA, Erie DA (2005). "DNA mismatch repair". Annual Review of Biochemistry. 74: 681–710. doi:10.1146/annurev... 79 KB (9,956 words) - 11:19, 14 March 2024 |
Hereditary nonpolyposis colorectal cancer (category DNA replication and repair-deficiency disorders) these cancers is due to inherited genetic mutations that impair DNA mismatch repair. It is a type of cancer syndrome. Other HNPCC conditions include... 47 KB (4,902 words) - 21:19, 19 February 2024 |
MutS is a mismatch DNA repair protein, originally described in Escherichia coli. Mismatch repair contributes to the overall fidelity of DNA replication... 8 KB (900 words) - 00:35, 16 December 2020 |
Powdery mildew (section DNA repair) needed] DNA mismatch repair (MMR) is an enzymatic system for recognizing and repairing erroneous base insertions, deletions, and mis-incorporations in DNA that... 27 KB (2,735 words) - 09:49, 9 April 2024 |
Cell damage (section DNA damage and repair) employed in repairing different types of DNA damages. These five pathways are nucleotide excision repair, base excision repair, mismatch repair, non-homologous... 23 KB (2,829 words) - 04:04, 16 January 2024 |
Base pair (redirect from Base pair mismatch) sequence of normal DNA base pairs. To repair mismatches formed during DNA replication, several distinctive repair processes have evolved to distinguish between... 32 KB (3,677 words) - 10:59, 1 December 2023 |
Chromosomal crossover (section DNA repair theory) Mismatch repair (MMR) proteins, for instance, are a well-known regulatory family of proteins, responsible for regulating mismatched sequences of DNA during... 32 KB (3,708 words) - 13:34, 2 March 2024 |
Crustacean (section DNA repair) associated with the DNA repair processes of non-homologous end joining, homologous recombination, base excision repair and DNA mismatch repair. The name "crustacean"... 57 KB (4,857 words) - 02:55, 13 April 2024 |
Plastid (section DNA damage and repair) integrity by repairing the plastid's DNA. For example, in chloroplasts of the moss Physcomitrella patens, a protein employed in DNA mismatch repair (Msh1) interacts... 29 KB (3,233 words) - 17:25, 15 April 2024 |
Cell (biology) (section DNA repair) organism with diverse well-defined DNA repair processes. These include: nucleotide excision repair, DNA mismatch repair, non-homologous end joining of double-strand... 62 KB (6,360 words) - 07:29, 17 April 2024 |
Nuclease (section Mismatch repair) the processing of Okazaki fragments. DNA mismatch repair in any given organism is effected by a suite of mismatch-specific endonucleases. In prokaryotes... 22 KB (2,535 words) - 04:02, 28 October 2023 |
levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pms2". Proceedings of the National Academy of Sciences. 94 (7):... 92 KB (10,484 words) - 07:21, 22 February 2024 |
Slipped strand mispairing (redirect from DNA slippage) joining, DNA mismatch repair or base excision repair may involve strand slippage mispairing leading to trinucleotide repeat expansion when the repair is completed... 10 KB (1,175 words) - 10:11, 22 March 2024 |
Cyanobacteria (section DNA repair) repair processes such as recombinational repair, nucleotide excision repair and methyl-directed DNA mismatch repair are common among cyanobacteria. Historically... 177 KB (17,513 words) - 15:18, 19 April 2024 |
deficiency (HRD): DNA double-strand break requires homologous recombination mechanism for accurate repair of breakpoints. DNA mismatch repair (MMR) deficiency:... 39 KB (4,037 words) - 23:13, 8 March 2024 |