• Deoxyribozymes, also called DNA enzymes, DNAzymes, or catalytic DNA, are DNA oligonucleotides that are capable of performing a specific chemical reaction...
    40 KB (4,795 words) - 07:48, 22 February 2024
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    applications such as preventing hormonal imbalance. Catalytic DNA (deoxyribozyme or DNAzyme) catalyze a reaction when interacting with the appropriate...
    43 KB (4,916 words) - 14:41, 5 April 2024
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    subunit of ribosomes. Several classes of ribozymes have been described. Deoxyribozymes, also called DNAzymes or catalytic DNA, are artificial DNA-based catalysts...
    48 KB (5,303 words) - 19:14, 1 February 2024
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    Keiper, Sonja; Vyle, Joseph S. (2006-05-12). "Reversible Photocontrol of Deoxyribozyme-Catalyzed RNA Cleavage under Multiple-Turnover Conditions". Angewandte...
    10 KB (809 words) - 11:18, 15 January 2024
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    Stojanovic, Milan N.; Mitchell, Tiffany E.; Stefanovic, Darko (2002). "Deoxyribozyme-Based Logic Gates". Journal of the American Chemical Society. 124 (14):...
    39 KB (3,459 words) - 02:37, 24 April 2024
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    are new methods to test paternity while a mother is still pregnant. Deoxyribozymes, also called DNAzymes or catalytic DNA, were first discovered in 1994...
    166 KB (17,845 words) - 19:31, 23 March 2024
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    also exhibit catalytic properties including ribozymes, and synthetic deoxyribozymes. Biocatalysts can be thought of as an intermediate between homogeneous...
    44 KB (5,012 words) - 11:06, 24 March 2024
  • work on in vitro evolution, for the discovery of the first DNA enzyme (deoxyribozyme), for his work in discovering potential RNA world ribozymes, and more...
    9 KB (764 words) - 06:22, 18 March 2024
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    sister ribozyme VS ribozyme Pistol ribozyme Hatchet ribozyme Viroids Deoxyribozyme Spiegelman Monster Catalysis Enzyme RNA world hypothesis Peptide nucleic...
    43 KB (5,181 words) - 17:07, 6 April 2024
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    Buchser WJ, Hurtado A, Grimpe B. (2012) Systemic administration of a deoxyribozyme to xylosyltransferase-1 mRNA promotes recovery after a spinal cord injury...
    12 KB (1,531 words) - 14:46, 3 December 2023
  • In 2016, she published the first X-ray structure of a DNA enzyme (deoxyribozyme) that catalyzes the ligation of two RNA fragments in Nature. She has...
    9 KB (984 words) - 16:28, 9 March 2024
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    non-natural aminoacids for an expanded genetic code. Biotin Dark quencher Deoxyribozyme Expanded genetic code Fluorophore Genetics Molecular biology Nucleic...
    48 KB (5,268 words) - 21:53, 2 March 2024
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    aptamers – Oligonucleotides which recognize the exosites of human thrombin Deoxyribozyme – DNA oligonucleotides that can perform a specific chemical reaction...
    60 KB (6,560 words) - 00:03, 20 April 2024
  • with Gerald Joyce. While at Scripps, he isolated the first DNA enzyme (deoxyribozyme). He joined the molecular, cellular, and developmental biology department...
    6 KB (412 words) - 11:58, 14 October 2023
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    mRNA was subjected to test-tube evolution to derive a catalytic DNA (Deoxyribozyme, also called DNAzyme) with RNA-cleavage activity. After only a few weeks...
    92 KB (10,688 words) - 10:08, 27 April 2024
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    structures and devices can be made using functional nucleic acids such as deoxyribozymes and ribozymes, which can perform chemical reactions, and aptamers, which...
    84 KB (9,648 words) - 04:25, 26 February 2024
  • Gerasimova, Yulia V. (March 2019). "Label-free pathogen detection by a deoxyribozyme cascade with visual signal readout". Sensors and Actuators B: Chemical...
    13 KB (1,586 words) - 19:04, 4 September 2023
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    Aptamer – Oligonucleotide or peptide molecules that bind specific targets Deoxyribozyme – DNA oligonucleotides that can perform a specific chemical reaction...
    41 KB (4,741 words) - 05:07, 22 April 2024
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    Erdmann, Volker A; Kurreck, Jens (May 2004). "Gaining Target Access for Deoxyribozymes". Journal of Molecular Biology. 339 (2): 355–363. doi:10.1016/j.jmb...
    14 KB (1,647 words) - 09:32, 3 December 2023
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    mercury. Chelation Luminescence Fluorescence Fluorophore Biosensor Deoxyribozyme Tomat, Elisa; Lippard, Stephen J (April 2010). "Imaging mobile zinc...
    19 KB (2,005 words) - 22:39, 27 May 2022
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    study of individuals suffering allergen-induced asthma, inhalation of Deoxyribozyme ST010, which specifically inactivates GATA3 messenger RNA, for 28 days...
    30 KB (3,740 words) - 12:03, 23 December 2023
  • wells coated with culture cells. The logic gates are made of the E6 Deoxyribozymes (or DNAzyme) which react to specific oligonucleotide input. Upon reaction...
    4 KB (446 words) - 13:14, 4 October 2022
  • Research (JJR), we were already exploring ways to exploit DNAzymes (deoxyribozymes) for diagnostic applications. These fascinating molecules are simple...
    10 KB (1,018 words) - 16:20, 17 August 2023
  • interest is in the identification, characterization, and application of deoxyribozymes, DNA used as a catalyst. "CAS Fellows Archive". Center for Advanced...
    3 KB (149 words) - 18:01, 20 July 2023