there are analogous definitions and uses for diastereomeric excess and percent diastereomeric excess. As an example, a sample with 70 % of R isomer...
5 KB (800 words) - 07:06, 10 May 2024
another. The degree of relative selectivity is measured by the diastereomeric excess. Stereoconvergence can be considered an opposite of stereospecificity...
8 KB (1,006 words) - 18:00, 19 January 2024
been depicted by Fuji et al. Based on different electrophile, the diastereomeric excess varied from 69% to 86. Protected at the aldehyde function with (R)-BINOL...
34 KB (3,692 words) - 20:40, 22 July 2024
amino acids to oligopeptides is possible with a yield of 95% and a diastereomeric excess of> 99% using the model substances Z-L-Phg-OH and L-H-Pro-NH2. In...
9 KB (898 words) - 18:07, 30 July 2024
5-substituted 2-morpholinones have been shown to induce good to excellent diastereomeric excess under different Petasis reaction conditions. Chiral N-acyliminium...
29 KB (3,232 words) - 12:16, 21 July 2024
as chiral solvent. The reported chemical yield is 66% with 60% diastereomeric excess Development of an unusually highly enantioselective hetero-Diels-Alder...
10 KB (963 words) - 02:41, 26 March 2024
chloride is also known as Mosher's acid chloride, and the resultant diastereomeric esters are known as Mosher's esters. Another system is Pirkle's Alcohol...
15 KB (1,818 words) - 23:00, 4 December 2023
(CH2)5CO, with benzaldehyde, C6H5CHO. At room temperature it produces a diastereomeric mixture of threo (63%) and erythro (19%) β-hydroxyketone as well as...
9 KB (958 words) - 06:34, 11 February 2024
properties of diastereomeric products, but rather on the different chemical properties of the racemic starting materials. The enantiomeric excess (ee) of the...
57 KB (6,914 words) - 13:54, 30 July 2024
alkynyl and perfluoroalkyl groups would give ketimines in a single diastereomeric form, which is critical for high stereoselectivities. The reaction is...
28 KB (3,407 words) - 00:21, 3 February 2024
1016/S0040-4039(00)91213-9. Narula, A. S. (1981). "An analysis of the diastereomeric transition state interactions for the kinetic deprotonation of acyclic...
21 KB (2,467 words) - 22:07, 14 August 2024
In the case of N-methyl piperidine, inversion at nitrogen between diastereomeric conformers is much faster than the rate of amine oxidation. The conformation...
29 KB (3,757 words) - 15:11, 13 February 2024
receptors in the central nervous system. SYM-2081 can be prepared through diastereomeric mixture via enzymatic synthesis, but the yield of this reaction is small...
4 KB (338 words) - 16:03, 3 November 2023
substrate molecule and which produces the stereoisomeric (enantiomeric or diastereomeric) products in unequal amounts." Put more simply: it is the synthesis...
41 KB (4,726 words) - 05:21, 27 May 2024
heart muscle) and fat cells. GLUT14 is expressed exclusively in testicles. Excess glucose is broken down and converted into fatty acids, which are stored...
121 KB (12,789 words) - 20:47, 6 September 2024
enantiotopic or enantiomorphic ester groups by the chiral enzyme are diastereomeric. Pig liver esterase (PLE) is a widely used enzyme for asymmetric ester...
11 KB (1,394 words) - 06:06, 7 March 2021
hydrogenation. Even a single methyl group is often sufficient to bias the diastereomeric outcome of the reaction. These studies, among others, helped challenge...
29 KB (3,680 words) - 11:33, 19 September 2024
enone group. The reaction step creates two stereocenters leading to two diastereomeric pairs of enantiomers. By the nature of the ABD skeleton the desired...
15 KB (1,662 words) - 02:08, 18 September 2024
R)-ethambutol, along with the achiral stereoisomer called meso-form, it holds a diastereomeric relationship with the optically active stereoisomers. The activity of...
41 KB (4,547 words) - 13:45, 15 August 2024
or in a substituent attached to the end of the double bond. Diastereomeric ratios in excess of 90:10 are common for these reactions; however, removal of...
13 KB (1,449 words) - 18:59, 23 January 2024
in the β position of the alkyl halide, reductive fragmentation to a diastereomeric mixture of alkenes may occur. β-Elimination of the intermediate organosamarium...
17 KB (1,966 words) - 20:27, 29 August 2024
Michael acceptors. This addition was performed with relatively high diastereomeric ratios for norbornene which favored addition to the endo position. Moreover...
29 KB (3,688 words) - 02:04, 18 March 2024
a simple case of a dinucleotide, this results in the formation of a diastereomeric pair of Sp- and Rp-dinucleoside monophosphorothioates whose structures...
79 KB (9,462 words) - 18:31, 28 January 2024
tetramethylenediamine (TMEDA) as a ligand produced syn-diols with a favorable diastereomeric ratio compared to Kishi’s protocol; however, stoichiometric osmium is...
17 KB (1,996 words) - 12:22, 28 March 2024
of borjatriol involved the rare isolation of a migrated epoxide. The diastereomeric mixture of rearrangement products was carried through the remainder...
14 KB (1,773 words) - 23:49, 28 April 2023
intermediates - XXXIX1 : Asymmetric synthesis of (enantiomerically and diastereomerically virtually pure) methyl 2-amino-4,5-epoxy-3-hydroxy-alkanoates and...
4 KB (444 words) - 19:38, 27 October 2022
compounds and obtained the thermodynamically controlled product. The diastereomeric ratio of the products is enhanced with bulkier R groups in the auxiliary...
15 KB (1,588 words) - 23:32, 28 February 2024
energy barriers between the diastereomeric transition states are of sufficient magnitude, then a high enantiomeric excess of one isomer is observed. Diels–Alder...
11 KB (1,242 words) - 23:24, 12 November 2023
Sieburth, S. M. (2004), "Silanediol peptidomimetics. Evaluation of four diastereomeric ACE inhibitors", Bioorganic & Medicinal Chemistry Letters, 14 (11):...
27 KB (3,409 words) - 06:47, 3 June 2024
Emmons produces the trans olefin. The published synthesis reveals a 1:1 diastereomeric mixture of the carbonyl reduction using zinc borohydride. However, years...
55 KB (5,643 words) - 08:54, 13 September 2024