Dihomo-γ-linolenic acid (DGLA) is a 20-carbon ω−6 fatty acid (also called, cis,cis,cis-8,11,14-eicosatrienoic acid). In physiological literature, it is...

gamma-Linolenic acid or GLA (γ-linolenic acid) (INN: gamolenic acid) is an n−6, or omega-6, fatty acid found primarily in seed oils. When acting on GLA...

11-trienoic acid, numerical representation 20:3 (5,8,11), n-9, molecular weight 306.48. CAS Registry Number 20590-32-3. Dihomo-γ-linolenic acid (dihomo-gamma-linolenic's...

conversion of LA into gamma-linolenic acid (GLA), effected by Δ6-desaturase. GLA is converted to dihomo-γ-linolenic acid (DGLA), the immediate precursor...

Epoxyeicosatetraenoic acid); c) Dihomo-γ-linolenic acid viz., 8,9-epoxy-eicosadienoic acid (8,9-EpEDE), 11,12-EpEDE, and 14,15-EpEDE; and d) Adrenic acid viz., 7...

regulation of signaling enzymes, such as PLC-γ, PLC-δ, and PKC-α, -β, and -γ isoforms, arachidonic acid is a key inflammatory intermediate and can also...

S (ed.). "5-Aminosalicylic Acid Ameliorates Colitis and Checks Dysbiotic Escherichia coli Expansion by Activating PPAR-γ Signaling in the Intestinal...

active metabolite of aspirin.: 235 : 17  Mefenamic acid Meclofenamic acid Flufenamic acid Tolfenamic acid Etofenamate Celecoxib (FDA alert) Rofecoxib (withdrawn...

their ALOX 15, metabolize dihomo-γ-linolenic acid (8Z,11Z,14Z-eicosatrienoic acid) to 15S-hydroperoxy-8Z,11Z,13E-eicosatrienoic acid and 15S-hydroxy-8Z,11Z...

other two cyclooxygenase isozymes are known to convert dihomo-γ-linolenic acid and arachidonic acid into prostaglandins, and are the targets of nonsteroidal...

typically comprises about 24% of the oil. GLA is converted to dihomo-γ-linolenic acid (DGLA), a precursor to a variety of the 1-series prostaglandins...

in leukocytes by the oxidation of arachidonic acid (AA) and the essential fatty acid eicosapentaenoic acid (EPA) by the enzyme arachidonate 5-lipoxygenase...

Aspirin, also known as acetylsalicylic acid (ASA), is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain, fever, and/or inflammation, and...

Salicylic acid is an organic compound with the formula HOC6H4COOH. A colorless (or, white), bitter-tasting solid, it is a precursor to and a metabolite...

use cinnamic acid as their starting point, which is derived from the amino acid phenylalanine. Plant biosynthesis starting with cinnamic acid is rare compared...

arachidonic acid. ALOX5's dioxygenase activity adds a hydroperoxyl (i.e. HO2) residue to arachidonic acid (i.e. 5Z,8Z,11Z,14Z-eicosatetraenoic acid) at carbon...

Dihomo-γ-linolenic acid, (8Z,11Z,14Z)-eicosatrienoic acid Mead acid, (5Z,8Z,11Z)-eicosatrienoic acid Sciadonic acid, (5Z,11Z,14Z)-eicosatrienoic acid...

organic compound with the formula C8H8O3. It is the methyl ester of salicylic acid. It is a colorless, viscous liquid with a sweet, fruity odor reminiscent...

Ricinoleic acid, formally called 12-hydroxy-9-cis-octadecenoic acid, is a fatty acid. It is an unsaturated omega-9 fatty acid and a hydroxy acid. It is a...

acid reaches the circulation, it is quickly metabolised in the liver by fatty acid beta oxidation to 1,2-dinor- and 1,2,3,4-tetranor-latanoprost acid;...

in polymorphonuclear cells at 1.8 μmol/L in vitro [56]. Inhibition of IFN-γ production, strong downregulation of CXCR3 expression on activated T cells...

Prostaglandin E1 is biosynthesized on an as-needed basis from dihomo-γ-linolenic acid (an omega-6 fatty acid) in healthy humans without coronary artery disease and/or...

Labelle M, Roy P, Xiang YB, Guay D, "Unsaturated hydroxyalkylquinoline acids as leukotriene antagonists", issued 15 October 1996, assigned to Merck Sharpe...

and other animals. They are derived enzymatically from the fatty acid arachidonic acid. Every prostaglandin contains 20 carbon atoms, including a 5-carbon...

COX-1. This reduces the generation of prostaglandins (PGs) from arachidonic acid. The clinical relevance of the drug stems from the role of PGs in the inflammation...

arachidonic acid to prostaglandin H2, an important precursor of prostacyclin, which is expressed in inflammation. PTGS2 (COX-2), converts arachidonic acid (AA)...

(9-cis-retinoic acid) may be used topically to help treat skin lesions from Kaposi's sarcoma, and tretinoin (all-trans- retinoic acid) is used to treat...

nonsteroidal anti-inflammatory drug (NSAID) of the carbazole and propionic acid class that was previously for use in humans and animals but is now only available...

combined with a proton-pump inhibitor (a medication that reduces stomach acid production) during long-term treatment of those with pre-existing stomach...

including thromboxane and prostaglandins such as prostacyclin, from arachidonic acid. A member of the animal-type heme peroxidase family, it is also known as...