Directed evolution (DE) is a method used in protein engineering that mimics the process of natural selection to steer proteins or nucleic acids toward...

The term directed evolution is used within the transhumanist community to refer to the idea of applying the principles of directed evolution and experimental...

Evolution is the change in the heritable characteristics of biological populations over successive generations. It occurs when evolutionary processes...

"Orthogenesis" (goal-directed evolution), "nomogenesis" (evolution according to fixed law), "emergent evolution", "creative evolution", and others. The Jesuit...

Steinberg, Barrett E. (16 April 2020). "SMOOT libraries and phage-induced directed evolution of Cas9 to engineer reduced off-target activity". PLOS ONE. 15 (4):...

selection as the organizing mechanism in evolution for a rectilinear (straight-line) model of directed evolution. With the emergence of the modern synthesis...

Teleology in biology is the use of the language of goal-directedness in accounts of evolutionary adaptation, which some biologists and philosophers of...

are used for the next round of mutagenesis. Protein Sequence space Directed evolution Protein engineering High-dimensional space DePristo, Mark A.; Weinreich...

synthetic biology.). Auxotrophy Biological dark matter Body plan Directed evolution Expanded genetic code Foldamer Hachimoji DNA Hypothetical types of...

Experimental evolution is the use of laboratory experiments or controlled field manipulations to explore evolutionary dynamics. Evolution may be observed...

the function of a protein. Directed evolution is the attempt to engineer proteins using methods inspired by molecular evolution. Change at one locus begins...

development of directed evolution methods was honored in 2018 with the awarding of the Nobel Prize in Chemistry to Frances Arnold for evolution of enzymes...

was awarded the Nobel Prize in Chemistry for pioneering the use of directed evolution to engineer enzymes. Since January 2021, she serves as an external...

outline is provided as an overview of and topical guide to evolution: In biology, evolution is change in the heritable characteristics of biological organisms...

identified by directed evolution. More recently (2024), snowflake yeast were subject to over 3,000 generations of further directed evolution, forming macroscopic...

particularly graph theory, and computer science, a directed acyclic graph (DAG) is a directed graph with no directed cycles. That is, it consists of vertices and...

Human evolution is the evolutionary process within the history of primates that led to the emergence of Homo sapiens as a distinct species of the hominid...

general strategies for protein engineering: rational protein design and directed evolution. These methods are not mutually exclusive; researchers will often...

Islamic views on evolution are diverse, ranging from theistic evolution to Old Earth creationism. Some Muslims around the world believe "humans and other...

design by directed evolution". Annu Rev Biophys. 37: 153–73. doi:10.1146/annurev.biophys.37.032807.125832. PMID 18573077. Maher B. (2009). "Evolution: Biology's...

rapid evolution of useful proteins. The lab has used PACE and its directed evolution efforts to generate new genome editing tools that allow for expanded...

Underworld: Evolution is a 2006 American action horror film directed by Len Wiseman from a screenplay by Danny McBride, based on a story by Wiseman and...

greater control over human biological nature through a process called directed evolution. Some thinkers believe that this may shatter our sense of self, and...

Alternatives to Darwinian evolution have been proposed by scholars investigating biology to explain signs of evolution and the relatedness of different...

The Mitsubishi Lancer Evolution, popularly referred to as the 'Evo', is a sports sedan and rally car based on the Lancer that was manufactured by Japanese...

Dragonball Evolution is a 2009 American science fantasy kung-fu action film directed by James Wong, produced by Stephen Chow, and written by Ben Ramsey...

and vertebrates were closer than invertebrates were. Although goal-directed evolution has been abandoned, the distinction of invertebrates and vertebrates...

Phage-assisted continuous evolution (PACE) is a phage-based technique for the automated directed evolution of proteins. It relies on relating the desired...

in vitro random recombination method to generate mutant genes for directed evolution and to enable a rapid increase in DNA library size. Three procedures...

Saturation mutagenesis is commonly used to generate variants for directed evolution. Sequence Saturation Mutagenesis Reetz, M. T.; Carballeira J. D. (2007)...