• Cephalosporins are a broad class of bactericidal antibiotics that include the β-lactam ring and share a structural similarity and mechanism of action with...
    33 KB (4,053 words) - 20:33, 27 March 2024
  • Thumbnail for Drug discovery
    of antiandrogens Discovery and development of cephalosporins Retrometabolic drug design "The drug development process". US Food and Drug Administration...
    58 KB (6,730 words) - 11:18, 6 May 2024
  • Thumbnail for Cephalosporin
    of β-lactam antibiotics called cephems. Cephalosporins were discovered in 1945, and first sold in 1964. The aerobic mold which yielded cephalosporin C...
    36 KB (2,507 words) - 07:09, 9 May 2024
  • Thumbnail for Beta-lactam antibiotics
    includes penicillin derivatives (penams), cephalosporins and cephamycins (cephems), monobactams, carbapenems and carbacephems. Most β-lactam antibiotics...
    34 KB (3,696 words) - 03:22, 8 March 2024
  • Thumbnail for Cephalosporin C
    discovery and production of many other cephalosporins. Cephalosporins are drugs used for some people who are allergic to penicillin. Cephalosporins are...
    5 KB (393 words) - 14:54, 8 March 2024
  • Thumbnail for Giuseppe Brotzu
    Giuseppe Brotzu (category Members of the Regional Council of Sardinia)
    PMID 10208039. Cephalosporin Discovery and development of cephalosporins Bo G (2000). "Giuseppe Brotzu and the discovery of cephalosporins". Clinical Microbiology...
    4 KB (319 words) - 03:56, 23 April 2024
  • Thumbnail for Cefpodoxime
    Cefpodoxime (category Cephalosporin antibiotics)
    gonorrhea. It also finds use as oral continuation therapy when intravenous cephalosporins (such as ceftriaxone) are no longer necessary for continued treatment...
    6 KB (399 words) - 01:26, 14 May 2024
  • Thumbnail for Cefoxitin
    Cefoxitin (category Cephalosporin antibiotics)
    cephalosporins. Cefoxitin requires a prescription and as of 2010 is sold under the brand name Mefoxin by Bioniche Pharma, LLC. The generic version of...
    26 KB (2,646 words) - 22:29, 25 March 2024
  • Edward Abraham (category Fellows of the American Academy of Arts and Sciences)
    commercially sold cephalosporin antibiotic Cefalotin sold by Eli Lilly and Company. There are now five generations of cephalosporins, of which some are among...
    17 KB (1,681 words) - 08:12, 12 May 2024
  • Thumbnail for Carbapenem
    (MDR) bacterial infections. Similar to penicillins and cephalosporins, carbapenems are members of the beta-lactam antibiotics drug class, which kill bacteria...
    30 KB (3,489 words) - 12:26, 15 December 2023
  • Thumbnail for Penicillin
    Penicillin (category Drugs developed by Eli Lilly and Company)
    avoidance, 90% of these patients can eventually tolerate penicillin. Additionally, those with penicillin allergies can usually tolerate cephalosporins (another...
    97 KB (10,497 words) - 19:07, 12 May 2024
  • Thumbnail for Beta-lactamase
    Beta-lactamase (category Enzymes of known structure)
    multi-resistance to beta-lactam antibiotics such as penicillins, cephalosporins, cephamycins, monobactams and carbapenems (ertapenem), although carbapenems are relatively...
    53 KB (6,263 words) - 18:38, 15 April 2024
  • Thumbnail for Cefotaxime
    Cefotaxime (category Cephalosporin antibiotics)
    antibiotic in the third-generation class of cephalosporins, cefotaxime is active against numerous Gram-positive and Gram-negative bacteria, including several...
    18 KB (1,677 words) - 21:41, 26 April 2024
  • Thumbnail for Ceftriaxone
    Ceftriaxone (category Cephalosporin antibiotics)
    Providencia, and Serratia, have the ability to become resistant through the development of cephalosporinases (enzymes that hydrolyze cephalosporins and render...
    34 KB (3,166 words) - 03:10, 4 May 2024
  • Thumbnail for History of penicillin
    history of penicillin follows observations and discoveries of evidence of antibiotic activity of the mould Penicillium that led to the development of penicillins...
    131 KB (16,722 words) - 13:42, 15 April 2024
  • Thumbnail for Pharmaceutical industry
    claims. The aftermath of World War II saw an explosion in the discovery of new classes of antibacterial drugs including the cephalosporins (developed by Eli...
    121 KB (12,730 words) - 05:59, 10 April 2024
  • Thumbnail for Alexander Fleming
    Alexander Fleming (category Fellows of the Royal College of Physicians of Edinburgh)
    Penicillins and Cephalosporins. Academic Press. pp. xxii. ISBN 978-1-4832-7719-6. Ward, John W.; Warren, Christian (2006). Silent Victories: The History and Practice...
    68 KB (7,610 words) - 13:40, 15 April 2024
  • Thumbnail for Impetigo
    Alternatively, amoxicillin combined with clavulanate potassium, cephalosporins (first-generation) and many others may also be used as an antibiotic treatment...
    21 KB (1,955 words) - 19:28, 16 March 2024
  • Thumbnail for Antibiotic
    (penicillins and cephalosporins) or the cell membrane (polymyxins), or interfere with essential bacterial enzymes (rifamycins, lipiarmycins, quinolones, and sulfonamides)...
    154 KB (14,470 words) - 01:32, 6 May 2024
  • Thumbnail for Proteus mirabilis
    from tetracycline and nitrofurantoin, but 10–20% of P. mirabilis strains are also resistant to first-generation cephalosporins and ampicillin. P. mirabilis...
    12 KB (1,254 words) - 05:11, 1 May 2024
  • Thumbnail for Thienamycin
    (penicillins, cephalosporins). Production of classic β-lactams in both fungi and bacteria occur through two steps: First, the condensation of l-cysteine...
    11 KB (1,191 words) - 03:33, 4 March 2024
  • Thumbnail for List of Italian inventions and discoveries
    Italian inventions and discoveries are objects, processes or techniques invented, innovated or discovered, partially or entirely, by Italians. Italian...
    237 KB (25,900 words) - 15:37, 9 May 2024
  • Thumbnail for Howard Florey
    Howard Florey (category Fellows of the American Academy of Arts and Sciences)
    pp. 269–272. Bo G (2000). "Giuseppe Brotzu and the discovery of cephalosporins". Clinical Microbiology and Infection. 6 (Suppl 3): 6–9. doi:10.1111/j...
    114 KB (13,582 words) - 20:49, 15 May 2024
  • Thumbnail for Typhoid fever
    "Treatment of typhoid fever and other systemic salmonelloses with cefotaxime, ceftriaxone, cefoperazone, and other newer cephalosporins". Reviews of Infectious...
    96 KB (10,569 words) - 14:31, 27 April 2024
  • Due to the discovery of penicillin by Alexander Fleming, and the efforts of Florey and Chain in 1938, large-scale, pharmaceutical production of antibiotics...
    22 KB (2,830 words) - 04:29, 4 May 2024
  • Thumbnail for Latamoxef
    Latamoxef (category Cephalosporin antibiotics)
    antibiotic usually grouped with the cephalosporins. In oxacephems such as latamoxef, the sulfur atom of the cephalosporin core is replaced with an oxygen...
    8 KB (728 words) - 14:53, 7 March 2024
  • Thumbnail for Natural product
    including penicillin and the cephalosporins (antibacterial drugs from Penicillium rubens and Cephalosporium acremonium, respectively) and griseofulvin (an...
    88 KB (9,571 words) - 23:47, 31 March 2024
  • industrially to produce the sugar alcohol erythritol.[citation needed] "Discovery and Development of Penicillin". American Chemical Society, International Historic...
    19 KB (1,718 words) - 19:43, 22 April 2024
  • Thumbnail for Serratia marcescens
    ampicillin, macrolides, and first-generation cephalosporins (such as cephalexin). In elkhorn coral, S. marcescens is the cause of the disease known as white...
    30 KB (3,251 words) - 00:44, 11 May 2024
  • Thumbnail for Flucloxacillin
    history of allergy to penicillins, cephalosporins, or carbapenems. It should also not be used in the eye, or administered to those with a history of cholestatic...
    23 KB (2,055 words) - 07:13, 14 March 2024