A double-strand break repair model refers to the various models of pathways that cells undertake to repair double strand-breaks (DSB). DSB repair is an...

additional error-prone inaccurate repair pathway for double-strand breaks. In MMEJ repair of a double-strand break, an homology of 5–25 complementary...

widely used by cells to accurately repair harmful DNA breaks that occur on both strands of DNA, known as double-strand breaks (DSB), in a process called homologous...

Synthesis-dependent strand annealing (SDSA) is a major mechanism of homology-directed repair of DNA double-strand breaks (DSBs). Although many of the features...

Homology-directed repair (HDR) is a mechanism in cells to repair double-strand DNA lesions. The most common form of HDR is homologous recombination. The...

but also as a mechanism for repair of double-strand breaks (DSBs) caused by DNA damage. These DSBs are usually repaired using the sister chromatid of...

complementary sequence analogous to double-strand-break repair. The filament searches for the homologous chromosome, strand invasion occurs where the new chromosome...

T. L. Orr-Weaver, R. J. Rothstein and F.W. Stahl, 1983 The double-strand-break repair model for recombination. Cell 33: 25-35. Foss, E., R. Lande, F. W...

LF (September 2003). "Regulation and mechanisms of mammalian double-strand break repair". Oncogene. 22 (37): 5792–812. doi:10.1038/sj.onc.1206679. PMID 12947387...

repair of double-strand breaks (DSBs). DSBs are often repaired using homology directed repair, a process which involves invasion of a template strand...

eukaryotes, two primary models for how homologous recombination repairs double-strand breaks in DNA are the double-strand break repair (DSBR) pathway (sometimes...

may specifically repair double-strand breaks (i.e. a break in both complementary strands of DNA). Single-strand breaks are repaired by DNA ligase using...

recombination: two different routes for double-strand break repair: the different functions of meiotic versus mitotic DSB repair are reflected in different pathway...

essential. DNA is made up of a double helix of two complementary strands. The double helix describes the appearance of a double-stranded DNA which is thus...

both normal cellular repair processes fail and cellular apoptosis does not occur. Specifically, Acharya noted that double-strand breaks and a "cross-linkage...

template strands to form two double helical DNA molecules. Multiple experiments were conducted to determine how DNA replicates. The semiconservative model was...

double-strand-breaks, which cleaves the DNA. Since only a small number of double-strand breaks are tolerated, and only a small number can be repaired...

"Involvement of nucleotide excision and mismatch repair mechanisms in double strand break repair". Current Genomics. 10 (4): 250–258. doi:10.2174/138920209788488544...

PARP-1 increased at the site of the double-strand break and components of the non-homologous end joining DNA repair pathway, including DNA-PKcs, Ku70/Ku80...

repair double-strand breaks, and this impairment may contribute to Down syndrome associated hematological abnormalities and malignancies. This model was...

the error-free repair of DNA double-strand breaks. If BRCA1 or BRCA2 itself is damaged by a BRCA mutation, damaged DNA is not repaired properly, and this...

performed by the protein RecA. During meiosis, repair of double-strand damages, particularly double-strand breaks, occurs by the recombination process outlined...

is a member of the RAD51 protein family which assists in repair of DNA double strand breaks. RAD51 family members are homologous to the bacterial RecA...

of double-strand DNA breaks prior to repair by homologous recombination or non-homologous end joining. The MRN complex binds avidly to double-strand breaks...

CpG sites within the double-strand break-associated insertion. Non-homologous end joining (NHEJ) repair of a double-strand break can cause a small number...

chromosomes. Repair of DNA double-strand breaks by accurate homologous recombination predominates over the inaccurate double-strand break repair pathway of...

insertions, deletions, and base-to-base conversions without the need for double strand breaks (DSBs) or donor DNA templates. The technology has received mainstream...

DNA-binding domain (DBD), double-strand breaks (DSBs) in target DNA by the restriction endonucleases (FokI and Cas), and the repair of DSBs through homology-directed...

is employed as a repair pathway when a double-strand break arises between direct repeat sequences in DNA. SSA involves single-strand resection, annealing...

helix. In triple-stranded DNA, the third strand binds to a B-form DNA (via Watson–Crick base-pairing) double helix by forming Hoogsteen base pairs or...