Active targeting of drug-loaded nanoparticles enhances the effects of passive targeting to make the nanoparticle more specific to a target site. There...

A biological target is anything within a living organism to which some other entity (like an endogenous ligand or a drug) is directed and/or binds, resulting...

of finding new medications based on the knowledge of a biological target. The drug is most commonly an organic small molecule that activates or inhibits...

are registered. Vintafolide is a small molecule drug conjugate consisting of a small molecule targeting the folate receptor. It is currently in clinical...

of Drug Targeting is a peer-reviewed medical journal published by Informa that covers research on all aspects of drug delivery and drug targeting for...

biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered by identifying...

drug is any chemical substance that when consumed causes a change in an organism's physiology, including its psychology, if applicable.[vague] Drugs are...

its target site to achieve a desired therapeutic effect. Principles related to drug preparation, route of administration, site-specific targeting, metabolism...

a special reversal form of drug delivery called chemotactic drug targeting. By using chemical agents to help guide a drug carrier to a specific location...

coating is also an effective method to obtain drug targeting (such as gastro-resistant drugs). Other drugs such as some anthelmintics may need to reach a...

delivery system. Mechanisms for drug targeting in the brain involve going either "through" or "behind" the BBB. Modalities for drug delivery to the brain in...

progress (by 2009) targeting these sites. Chemoproteomics techniques have recently expanded the scope of what is deemed a druggable target through the identification...

(anticancer) payload or drug. Antibody–drug conjugates are an example of bioconjugates and immunoconjugates. ADCs combine the targeting properties of monoclonal...

topoisomerase inhibitors (i.e. etoposide, doxorubicin), microtubule-targeted drugs (i.e. vinblastine), and tyrosine kinase inhibitors (i.e. gefitinib,...

The DrugBank database is a comprehensive, freely accessible, online database containing information on drugs and drug targets created and maintained by...

pharmacokinetic (drug absorption, distribution, metabolism, and elimination), pharmacodynamic (effects mediated through a drug's biological targets), and/or immunogenic...

Target-mediated drug disposition (TMDD), is the process in which a drug binds with high affinity to its pharmacological target (for example, a receptor)...

than one drug, it is said to be multidrug-resistant. The development of antibiotic resistance in particular stems from the drugs targeting only specific...

accessories Original Use, male clothing brand targeting gen-Z and millennials Wild Fable, women's clothing brand targeting gen-Z Made By Design, a homelines brand...

effective measures to be taken by countries to tackle drug trafficking; for example, targeting specific criminal organisations that are often also active...

Pharmacology is the science of drugs and medications, including a substance's origin, composition, pharmacokinetics, pharmacodynamics, therapeutic use...

binding to the same biological target), similar modes of action, and/or are used to treat the similar diseases. The Food and Drug Administration (FDA) has worked...

Antiviral drugs are a class of medication used for treating viral infections. Most antivirals target specific viruses, while a broad-spectrum antiviral...

achieve drug targeting at a selected organ or site, SDs are designed to afford a differential distribution that can be regarded as reverse targeting. Since...

have been one such target in clinical trials. This B7-H3 protein is expressed on cancer cell for several types of cancer. Often, the drug will contain two...

results, this indicates the prosperity of further developing a single drug targeting HSDD for all women of different status, even though the FDA has not...

phenotypic drug discovery, a paradigm that aims to discover lead compounds on the basis of alleviating a disease phenotype, as opposed to target-based drug discovery...

transmucosal drug delivery. The retro-Michael reactions resulting in maleimide-thiol adducts require precise control. The targeting ability of drugs containing...

Drug Target Insights is a peer-reviewed open access academic journal focusing on drug treatment targets and clinical therapeutics. The journal was founded...

antiepileptic drugs, since GABA can itself, directly or indirectly, act proconvulsively. Another potential target of antiepileptic drugs is the peroxisome...