Drug metabolism is the metabolic breakdown of drugs by living organisms, usually through specialized enzymatic systems. More generally, xenobiotic metabolism...

and vinyl chloride. Drugs continue to be taken off the market due to late discovery of hepatotoxicity. Due to its unique metabolism and close relationship...

foods, beverages, or other drugs. A popular example of drug-food interaction is the effect of grapefruit in the metabolism of drugs. Interactions may occur...

pass effect (also known as first-pass metabolism or presystemic metabolism) is a phenomenon of drug metabolism at a specific location in the body which...

Molecule Drug Metabolism". Ionsource.com. September 1, 2012. Retrieved April 21, 2013. "Comparison of the Levels of Enzymes Involved in Drug Metabolism between...

Drug Metabolism and Disposition is a peer-reviewed scientific journal covering the fields of pharmacology and toxicology. It was established in 1973 and...

Metabolism (/məˈtæbəlɪzəm/, from Greek: μεταβολή metabolē, "change") is the set of life-sustaining chemical reactions in organisms. The three main functions...

Grapefruit–drug interactions that affect the pre-systemic metabolism (i.e., the metabolism that occurs before the drug enters the blood) of drugs have a different...

and illicit drugs, extensive food-drug and drug-drug interactions as well as ADMET (absorption, distribution, metabolism, excretion and toxicity) parameters...

effect or expected/normal responses (especially based on drug metabolism). Abnormal drug metabolism may be due to inherited factors of either Phase I oxidation...

as for hormone synthesis and breakdown, steroid hormone synthesis, drug metabolism, and the biosynthesis of defensive compounds, fatty acids, and hormones...

context of chemical biology and medicine. He has also worked on drug discovery, drug metabolism, and translational research. Swamidass is the founder of "Peaceful...

Current Drug Metabolism is a peer-reviewed medical journal covering the study of drug metabolism. It was established in 2000 and is published 10 times...

predict or evaluate the metabolism of pharmaceutical compounds, and to better understand the pharmacokinetic profile of a drug. Pharmacometabolomics can...

enzymes. Several other members of this family are also involved in drug metabolism, but CYP3A4 is the most common and the most versatile one. Like all...

the route of drug administration is important because it affects drug metabolism, drug clearance, and thus dosage. The term is from Greek enteros 'intestine'...

enzyme protein. The enzyme is involved in the metabolism, by oxidation, of both xenobiotics, including drugs, and endogenous compounds, including fatty acids...

a drug when they can tolerate its adverse effects. Some instances of drug intolerance are known to result from genetic variations in drug metabolism. Drugs...

contrary, gut microbiota may also alter the metabolism of the drugs by modulating the host drug metabolism. This mechanism can be mediated by microbial...

(MAO) intermediate products. AO plays an important role in the metabolism of several drugs. AO catalyzes the conversion of an aldehyde in the presence of...

majority of small-molecule drug metabolism is carried out in the liver by redox enzymes, termed cytochrome P450 enzymes. As metabolism occurs, the initial (parent)...

Established in 1972, Drug Metabolism Reviews is an academic journal that publishes review articles on all aspects of drug metabolism research. It is the...

organosulfur inducers of phase 2 enzymes: dithiolethiones and dithiins". Drug Metabolism and Drug Interactions. 17 (1–4): 3–22. doi:10.1515/DMDI.2000.17.1-4.3. PMID 11201301...

superfamily of enzymes. CYP1A1 is involved in phase I xenobiotic and drug metabolism (one substrate of it is theophylline). It is inhibited by hesperetin...

suspension or culture to explore mechanisms of drug metabolism and even predict in vivo drug metabolism. For these purposes, hepatocytes are usually isolated...

PMID 26361585. Docampo R, Moreno SN (1990). "The metabolism and mode of action of gentian violet". Drug Metabolism Reviews. 22 (2–3): 161–78. doi:10.3109/03602539009041083...

5-methoxy-N,N-dimethyltryptamine: metabolism, pharmacokinetics, drug interactions, and pharmacological actions". Current Drug Metabolism. 11 (8): 659–666. doi:10...

monooxygenases: structure/function, genetic polymorphisms and role in drug metabolism". Pharmacology & Therapeutics. 106 (3): 357–387. doi:10.1016/j.pharmthera...

Expert Opinion on Drug Metabolism & Toxicology is a monthly peer-reviewed medical journal publishing review articles on ADME-Tox. It was established in...

absorption and first-pass metabolism. Thereby, mathematically, bioavailability equals the ratio of comparing the area under the plasma drug concentration curve...