• Thumbnail for ED50
    ED50 ("European Datum 1950", EPSG:4230) is a geodetic datum which was defined after World War II for the international connection of geodetic networks...
    8 KB (928 words) - 18:08, 2 August 2023
  • desired pharmacological effect (e.g. efficacious dose in 50% of subjects, ED50). In contrast, in a drug development setting TI is calculated based on plasma...
    25 KB (3,163 words) - 09:01, 11 April 2024
  • It is also sometimes abbreviated as the ED50, meaning "effective dose for 50% of the population". The ED50 is commonly used as a measure of the reasonable...
    6 KB (684 words) - 16:56, 21 January 2024
  • Thumbnail for Geographic coordinate system
    cartographical organization include the North American Datum, the European ED50, and the British OSGB36. Given a location, the datum provides the latitude...
    21 KB (2,380 words) - 18:12, 4 April 2024
  • Thumbnail for Median toxic dose
    category of toxicity that is greater than half maximum effective concentration (ED50) but less than the median lethal dose (LD50). However, for some highly potent...
    2 KB (260 words) - 14:51, 24 February 2024
  • Thumbnail for Ordnance Survey National Grid
    halfway between Dover and Calais, the ED50 longitude lines are about 20 m east of the OSGB36 equivalents, and the ED50 latitude lines are about 150 m south...
    19 KB (2,130 words) - 10:22, 14 April 2024
  • Thumbnail for Haloperidol
    D2 and α1 receptors at low dose (ED50 = 0.13 and 0.42 mg/kg, respectively), and 5-HT2 receptors at a higher dose (ED50 = 2.6 mg/kg). Given that antagonism...
    56 KB (4,889 words) - 23:59, 2 April 2024
  • effective dose (ED50). Therefore, it is more useful to compare such substances by therapeutic index, which is simply the ratio of LD50 to ED50.[citation needed]...
    52 KB (3,860 words) - 12:35, 31 March 2024
  • Thumbnail for Bromazolam
    resulted in full dose-dependent substitution with an ED50 of 0.54 mg/kg. In comparison the ED50 of midazolam and diazepam were 0.09 and 0.66 respectively...
    20 KB (2,075 words) - 18:54, 16 April 2024
  • Thumbnail for Lacosamide
    preventing the spread of seizures induced by MES in mice (ED50 = 4.5 mg/kg, i.p.) and rats (ED50 = 3.9 mg/kg, p.o.). In preclinical trials, administration...
    40 KB (3,809 words) - 09:28, 9 January 2024
  • Thumbnail for Geodetic datum
    spherical harmonics. Other datums are defined for other areas or at other times; ED50 was defined in 1950 over Europe and differs from WGS 84 by a few hundred...
    29 KB (3,073 words) - 16:06, 31 December 2023
  • Thumbnail for 4-Fluoromethylphenidate
    potential as anti-cocaine medications. 4F-MPH was reported as having an ED50 mg/kg of 0.26 (0.18–0.36), regarding its efficacy as a substitute for cocaine...
    6 KB (513 words) - 15:02, 17 June 2023
  • Thumbnail for Mulhacén
    National Mapping Agency. The coordinates given here have been converted from ED50 to WGS84. "European ultra-prominent peaks". peakList.org. Retrieved 24 January...
    5 KB (482 words) - 18:34, 31 March 2024
  • Thumbnail for Latitude
    longitude of 2° 17′ 40″ E or 2.2944°E. The same coordinates on the datum ED50 define a point on the ground which is 140 metres (460 feet) distant from...
    47 KB (6,180 words) - 10:19, 3 April 2024
  • Thumbnail for World Geodetic System
    information. The inability of the large geodetic systems, such as European Datum (ED50), North American Datum (NAD), and Tokyo Datum (TD), to provide a worldwide...
    24 KB (2,809 words) - 05:56, 18 March 2024
  • Thumbnail for Global Positioning System
    OSGB36 Ordnance Survey Great Britain 1936 SK-42 Systema Koordinat 1942 goda ED50 European Datum 1950 SAD69 South American Datum 1969 GRS 80 Geodetic Reference...
    177 KB (18,448 words) - 19:11, 19 April 2024
  • Thumbnail for Florence
    subdivided according to the sampling year. Coordinates refer to UTM32T (ED50) system. "World map of Köppen – Geiger Climate Classification". koeppen-geiger...
    125 KB (13,554 words) - 02:04, 20 April 2024
  • Thumbnail for Helmert transformation
    ellipsoid. A further datum of interest was ED50 (European Datum 1950) based on the Hayford ellipsoid. ED50 was part of the fundamentals of the NATO coordinates...
    14 KB (1,277 words) - 12:39, 10 January 2023
  • Thumbnail for Agonist
    relationship, termed the therapeutic index, is defined as the ratio TD50:ED50. In general, the narrower this margin, the more likely it is that the drug...
    14 KB (1,618 words) - 23:34, 19 April 2024
  • Thumbnail for Earth's circumference
    OSGB36 Ordnance Survey Great Britain 1936 SK-42 Systema Koordinat 1942 goda ED50 European Datum 1950 SAD69 South American Datum 1969 GRS 80 Geodetic Reference...
    21 KB (2,446 words) - 05:28, 10 December 2023
  • Thumbnail for EPSG Geodetic Parameter Dataset
    OSGB36 Ordnance Survey Great Britain 1936 SK-42 Systema Koordinat 1942 goda ED50 European Datum 1950 SAD69 South American Datum 1969 GRS 80 Geodetic Reference...
    5 KB (448 words) - 13:19, 16 January 2024
  • Thumbnail for Dose–response relationship
    the dose response curve reflect measures of potency (such as EC50, IC50, ED50, etc.) and measures of efficacy (such as tissue, cell or population response)...
    17 KB (1,788 words) - 12:43, 12 December 2023
  • Thumbnail for Universal Transverse Mercator coordinate system
    OSGB36 Ordnance Survey Great Britain 1936 SK-42 Systema Koordinat 1942 goda ED50 European Datum 1950 SAD69 South American Datum 1969 GRS 80 Geodetic Reference...
    17 KB (2,610 words) - 23:05, 29 February 2024
  • Thumbnail for European Terrestrial Reference System 1989
    minor refinements in later editions since its initial publication. WGS 84. ED50. AFREF. Degrees minutes seconds (DMS). Geodetic datum. KMZ file, a zipped...
    6 KB (585 words) - 18:43, 20 March 2024
  • Thumbnail for North American Vertical Datum of 1988
    OSGB36 Ordnance Survey Great Britain 1936 SK-42 Systema Koordinat 1942 goda ED50 European Datum 1950 SAD69 South American Datum 1969 GRS 80 Geodetic Reference...
    7 KB (732 words) - 16:18, 31 January 2024
  • Thumbnail for Phenylpiracetam hydrazide
    investigated as anticonvulsants. In an electroshock test it was found to have an ED50 of 310 mg/kg. All piracetam derivatives are not permitted to be sold as dietary...
    4 KB (242 words) - 03:30, 18 December 2023
  • Thumbnail for Longitude
    OSGB36 Ordnance Survey Great Britain 1936 SK-42 Systema Koordinat 1942 goda ED50 European Datum 1950 SAD69 South American Datum 1969 GRS 80 Geodetic Reference...
    35 KB (4,148 words) - 23:48, 2 April 2024
  • Thumbnail for Cycloheptyl CP 55,940
    Cycloheptyl CP 55,940 has similar potency to CP 55,940 itself, with an ED50 of 0.06 mg/kg in animal studies. Abeo-HHC acetate CP 47,497 O-1656 US 4371720...
    2 KB (106 words) - 12:27, 14 April 2024
  • Thumbnail for 4-Methylaminorex
    4-methylaminorex can be smoked, insufflated or taken orally. As an anorectic, the ED50 is 8.8 mg/kg in rats for the (±)-cis isomers. The (±)-trans isomers are slightly...
    17 KB (1,802 words) - 11:42, 16 January 2024
  • Thumbnail for Furanylfentanyl
    is an analog of fentanyl and has been sold as a designer drug. It has an ED50 value of 0.02 mg/kg in mice. This makes it approximately one fifth as potent...
    9 KB (905 words) - 04:47, 21 November 2023