• Thumbnail for Echinocandin
    Echinocandins are a class of antifungal drugs that inhibit the synthesis of β-glucan in the fungal cell wall via noncompetitive inhibition of the enzyme...
    17 KB (1,900 words) - 16:51, 1 October 2023
  • Thumbnail for Echinocandin B
    Echinocandin B, a lipopeptide, is a naturally occurring cyclic hexapeptide with a linoleoyl side chain. It belongs to a class of antifungal agents called...
    5 KB (281 words) - 18:01, 22 February 2024
  • Thumbnail for Micafungin
    Micafungin (category Echinocandins)
    Micafungin, sold under the brand name Mycamine, is an echinocandin antifungal medication used to treat and prevent invasive fungal infections including...
    9 KB (529 words) - 14:22, 24 March 2024
  • Thumbnail for Antifungal
    synthesis. Examples include butenafine, naftifine, and terbinafine. Echinocandins inhibit the creation of glucan in the fungal cell wall by inhibiting...
    28 KB (2,564 words) - 04:52, 24 February 2024
  • Thumbnail for Pneumocandin B0
    Pneumocandin B0, also known as pneumocandin B0, pneumocandin B(0), and hydroxy echinocandin, is an organic chemical compound with the formula C50H80N8O17, produced...
    9 KB (767 words) - 22:13, 18 December 2022
  • Thumbnail for Rezafungin
    Rezafungin (category Echinocandins)
    medication used for the treatment of invasive candidiasis. It is an echinocandin antifungal. Rezafungin was approved for medical use in the United States...
    7 KB (424 words) - 12:49, 16 April 2024
  • important. They represent a drug target for antifungal medications of the echinocandin class. The following are glucans (The α- and β- and numbers clarify the...
    7 KB (936 words) - 08:41, 22 June 2023
  • Thumbnail for Fluconazole
    antifungal drugs of class echinocandins, recommended as the first method of treatment against invasive candidiasis. The three echinocandins currently licensed...
    31 KB (2,821 words) - 06:54, 6 May 2024
  • Thumbnail for Anidulafungin
    Anidulafungin (category Echinocandins)
    Anidulafungin (INN): 42  (trade names Eraxis, Ecalta) is a semisynthetic echinocandin used as an antifungal drug. It was previously known as LY303366. It may...
    14 KB (1,045 words) - 14:22, 24 March 2024
  • Thumbnail for Candidiasis
    infections, including clotrimazole. In those with widespread disease, an echinocandin such as caspofungin or micafungin is used. A number of weeks of intravenous...
    66 KB (6,310 words) - 23:06, 25 April 2024
  • Thumbnail for Candida tropicalis
    peripheral organs. For invasive disease, treatments include amphotericin B, echinocandins, or extended-spectrum triazole antifungals. In the history of fungi...
    26 KB (2,783 words) - 15:11, 26 February 2024
  • medication. Common anti-fungal drugs for internal infections include the echinocandin family of drugs and fluconazole. While algae are commonly not thought...
    41 KB (4,224 words) - 12:37, 21 April 2024
  • increased use of echinocandins. Insufficient dosing of azoles has also led to the emergence of resistance. Observed rates of echinocandin resistance for...
    16 KB (1,629 words) - 02:42, 24 November 2023
  • Thumbnail for Aspergillus nidulans
    ascospores. Anidulafungin is a semisynthetic lipopeptide antifungal drug of echinocandin B subclass, derived from a fermentation product of A. nidulans var. echinulatus...
    7 KB (767 words) - 17:40, 10 January 2024
  • Thumbnail for Candida auris
    resistant to amphotericin B; however, most isolates are susceptible to echinocandins. Treatment is complicated because C. auris is easily misidentified as...
    27 KB (2,789 words) - 21:07, 4 May 2024
  • methylbenzaldehyde, 2,4-dihydroxy-6-(hydroxymethyl)-benzaldehyde, echinocandin B, echinocandin C, echinocandin D, epishamixanthone, shamixanthone, 14-Hydroxytajixanthone...
    2 KB (192 words) - 19:06, 13 January 2024
  • arugosin C, asperthecin, aspertetronin A, aspertetronin B, echinocandin B, echinocandin C, echinocandin D, epishamixanthone, shamixanthone, orsellinaldehyde...
    2 KB (162 words) - 00:20, 19 April 2024
  • Thumbnail for Mechanism of action
    "New developments and directions in the clinical application of the echinocandins". Archives of Toxicology. 91 (4): 1613–1621. doi:10.1007/s00204-016-1916-3...
    17 KB (1,849 words) - 11:51, 25 December 2023
  • sterigmatocystin, versicolourin, desferritriacetylfusigen, echinocandin B, echinocandin E, emericellin, emestrin, aurantioemestrin, dethiosecoemestrin...
    2 KB (124 words) - 17:12, 16 January 2024
  • Thumbnail for Caspofungin
    Caspofungin (category Echinocandins)
    Merck & Co., Inc.. It is a member of a class of antifungals termed the echinocandins.[medical citation needed] It works by inhibiting the enzyme (1→3)-β-D-glucan...
    16 KB (1,178 words) - 23:43, 30 March 2024
  • Thumbnail for Fungemia
    vs non-neutropenic candidemia is treated differently. An intravenous echinocandin such as anidulafungin, caspofungin or micafungin is recommended as first-line...
    9 KB (825 words) - 10:26, 1 March 2024
  • Thumbnail for Aspergillus fumigatus
    azoles, other anti-fungal drug classes do exist such as polyenes and echinocandins.[citation needed] Conidia phialoconidia of A. fumigatus Colony in Petri...
    44 KB (4,593 words) - 16:31, 10 January 2024
  • Thumbnail for Nakaseomyces glabratus
    resistant to common treatments like fluconazole. N. glabratus resistance to Echinocandin is also increasing, leaving expensive and toxic antifungal treatments...
    11 KB (1,260 words) - 17:34, 26 March 2024
  • Thumbnail for Sepsis
    macrolide or fluoroquinolone is chosen. If fungal infection is suspected, an echinocandin, such as caspofungin or micafungin, is chosen for people with severe...
    124 KB (13,537 words) - 04:32, 22 April 2024
  • Thumbnail for Coccidioides immitis
    structure to fluconazole) and caspofungin (glucan synthesis inhibitor of the echinocandin structural class). However, these drugs have not been FDA approved, and...
    16 KB (1,754 words) - 01:11, 23 March 2024
  • from Glarea lozoyensis. Strobilurin, azoxystrobin, micafungin, and echinocandins, are all extracted from fungi. Anidulafungin is a derivative of an Aspergillus...
    19 KB (1,718 words) - 19:43, 22 April 2024
  • first described in 2016. It has been reported to produce asperthecin, echinocandin B1, desferritriacetylfusigen, and sterigmatocystin. In 2016, the genome...
    2 KB (237 words) - 00:19, 19 April 2024
  • acid, 6,7,8-trihydroxy-3-methylisocoumarin, desferritriacetylfusigen, echinocandin B, and sterigmatocystin. A. navahoensis has been cultivated on both Czapek...
    3 KB (266 words) - 16:31, 16 January 2024
  • Thumbnail for Glycosyltransferase
    glycosyltransferases, the nikkomycins, inhibitors of chitin synthase, and the echinocandins, inhibitors of fungal β-1,3-glucan synthases. Some glycosyltransferase...
    13 KB (1,551 words) - 14:54, 5 February 2024
  • can be successfully treated with voriconazole, amphotericin B, and echinocandins (micafungin, caspofungin, and anidulafungin).[citation needed] Cacao...
    6 KB (553 words) - 04:57, 19 April 2024