chemistry, an electrophile is a chemical species that forms bonds with nucleophiles by accepting an electron pair. Because electrophiles accept electrons...

positive or partially positive atom becomes an electrophile. The whole molecular entity of which the electrophile and the leaving group are part is usually...

Cross electrophile coupling is a type of cross-coupling reaction that occurs between two electrophiles often catalyzed by transition metal catalyst(s)...

Electrophilic substitution reactions are chemical reactions in which an electrophile displaces a functional group in a compound, which is typically, but not...

attached to an aromatic system (usually hydrogen) is replaced by an electrophile. Some of the most important electrophilic aromatic substitutions are...

atoms carries a partial positive charge. This makes the molecule an electrophile, and the carbon atom the electrophilic center; this atom is the primary...

chemical compound containing a carbonyl group (C=O) acts both as the electrophile and the nucleophile in an aldol condensation. It is also called a symmetrical...

relates to rates of certain chemical reactions. The terms nucleophile and electrophile were introduced by Christopher Kelk Ingold in 1933, replacing the terms...

these reactions, the conjugate acid of the carbonyl group is a better electrophile than the neutral carbonyl group itself. Depending on the chemical species...

Phosphorus trichloride is an inorganic compound with the chemical formula PCl3. A colorless liquid when pure, it is an important industrial chemical, being...

reacts as the nucleophile with another organic compound acting as the electrophile. This sense of reactivity may be reversed for some electron-deficient...

nucleophile and electrophile are different, the reaction is called a crossed aldol reaction; on the converse, when the nucleophile and electrophile are the same...

attacking atom or molecule, an electrophile, has low electron density and thus a positive charge. Typical electrophiles are the carbon atom of carbonyl...

include phenyllithium (C6H5Li) and phenylmagnesium bromide (C6H5MgBr). Electrophiles are attacked by benzene to give phenyl derivatives: C 6 H 6 + E + ⟶...

refer it as an effect produced by the presence of a reagent like an electrophile or a nucleophile, IUPAC does not define it as such. The term electromeric...

are electrophilic aromatic substitution, when the active reagent is an electrophile, and nucleophilic aromatic substitution, when the reagent is a nucleophile...

σ bonds. The driving force for this reaction is the formation of an electrophile X+ that forms a covalent bond with an electron-rich, unsaturated C=C...

Electrophilic substitution of unsaturated silanes involves attack of an electrophile on an allyl- or vinylsilane. An allyl or vinyl group is incorporated...

form an azaenolate, which reacts with alkyl halides or other suitable electrophiles to give alkylated hydrazone species with the simultaneous generation...

ester synthesis, wherein the diester of malonic acid reacts with an electrophile (e.g., alkyl halide), and is subsequently decarboxylated. Another variation...

Dicobalt octacarbonyl is an organocobalt compound with composition Co2(CO)8. This metal carbonyl is used as a reagent and catalyst in organometallic chemistry...

: the ability of the nucleophilic group to donate electrons and the electrophile to accept them. The former one is mainly affected by the basicity(the...

Grignard reagents also react with many "carbonyl-like" compounds and other electrophiles: Grignard reagents serve as a base for non-protic substrates (this scheme...

temperature) Reducing Yes (Pd/H2,Na/NH3), Zn/HCl: No (strong acid) Oxidative Yes Nucleophile Yes (exception of F−) Electrophile Yes Radical Yes Carbene Yes...

to the contributions of Gilbert N. Lewis. The terms nucleophile and electrophile are sometimes interchangeable with Lewis base and Lewis acid, respectively...

acid anhydride derived from triflic acid. This compound is a strong electrophile, useful for introducing the triflyl group, CF3SO2. Abbreviated Tf2O,...

the resulting enolate with an electrophile at the α-position. When the nucleophile is an enolate and the electrophile a proton, the reaction is called...

another electron-deficient molecule (known as the electrophile). The molecule that contains the electrophile and the leaving functional group is called the...

toward nucleophilic addition and the tendency for the enolates to add to electrophiles. Nucleophilic additions include in approximate order of their generality:...

acid–base theory or Brønsted–Lowry acid–base theory E: any element or electrophile L: any ligand Ln: any lanthanide M: any metal Mm: mischmetal (occasionally...