• Thumbnail for Enzyme inhibitor
    An enzyme inhibitor is a molecule that binds to an enzyme and blocks its activity. Enzymes are proteins that speed up chemical reactions necessary for...
    104 KB (11,575 words) - 10:05, 2 March 2024
  • Thumbnail for ACE inhibitor
    lowering blood pressure. As a result of inhibiting the ACE enzyme in the bradykinin system, the ACE inhibitor drugs allow for increased levels of bradykinin...
    64 KB (7,001 words) - 18:04, 27 April 2024
  • Thumbnail for Enzyme
    and the inhibitor affect each other. The enzyme's function is reduced but not eliminated when bound to the inhibitor. This type of inhibitor does not...
    96 KB (9,774 words) - 02:03, 3 April 2024
  • Thumbnail for Active site
    active site and an enzyme inhibitor. If the enzyme found in bacteria is significantly different from the human enzyme then an inhibitor can be designed against...
    40 KB (4,839 words) - 23:49, 6 November 2023
  • Thumbnail for Monoamine oxidase inhibitor
    Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A)...
    36 KB (3,892 words) - 14:47, 27 March 2024
  • affinity for the substrate in the enzyme is decreased in the presence of an inhibitor. The inhibitor may bind to the enzyme whether or not the substrate has...
    14 KB (1,806 words) - 21:00, 7 October 2023
  • Thumbnail for Angioedema
    inherited problem known as C1 esterase inhibitor deficiency, medications known as angiotensin-converting enzyme inhibitors, or a lymphoproliferative disorder...
    26 KB (2,973 words) - 06:28, 12 April 2024
  • Thumbnail for Enzyme kinetics
    activity is controlled, and how a drug or a modifier (inhibitor or activator) might affect the rate. An enzyme (E) is a protein molecule that serves as a biological...
    71 KB (9,343 words) - 13:26, 1 February 2024
  • inhibition or inhibitor in Wiktionary, the free dictionary. Inhibitor or inhibition may refer to: Enzyme inhibitor, a substance that binds to an enzyme and decreases...
    2 KB (271 words) - 19:42, 25 May 2023
  • Thumbnail for Suicide inhibition
    inhibitor binds to the active site where it is modified by the enzyme to produce a reactive group that reacts irreversibly to form a stable inhibitor-enzyme...
    5 KB (589 words) - 14:06, 14 November 2023
  • Thumbnail for Angiotensin-converting enzyme
    ISBN 978-3-319-09787-9. Dicpinigaitis PV (January 2006). "Angiotensin-converting enzyme inhibitor-induced cough: ACCP evidence-based clinical practice guidelines". Chest...
    24 KB (2,536 words) - 02:33, 8 March 2024
  • Thumbnail for Competitive inhibition
    competitive inhibition of enzyme catalysis, binding of an inhibitor prevents binding of the target molecule of the enzyme, also known as the substrate...
    22 KB (2,864 words) - 20:03, 19 December 2023
  • Thumbnail for Protease
    Protease (redirect from Proteolytic enzyme)
    Protease inhibitor (pharmacology) Protease inhibitor (biology) TopFIND - database of protease specificity, substrates, products and inhibitors MEROPS -...
    26 KB (2,799 words) - 22:42, 25 April 2024
  • Thumbnail for Aromatic L-amino acid decarboxylase inhibitor
    decarboxylase inhibitor (synonyms: DOPA decarboxylase inhibitor, Extracerebral decarboxylase inhibitor, DDCI and AAADI) is a medication of type enzyme inhibitor which...
    4 KB (395 words) - 12:44, 5 November 2022
  • of COX-2 inhibitors. The inhibition of COX-2 is paramount for the anti-inflammatory and analgesic function of the selective COX-2 inhibitor celecoxib...
    42 KB (4,944 words) - 11:56, 4 April 2024
  • neurodegenerative diseases. Enzyme inducers can be either naturally occurring or synthetically made. Enzyme activator Enzyme inhibitor Regulation of gene expression...
    2 KB (170 words) - 00:11, 14 October 2023
  • Thumbnail for Proton-pump inhibitor
    target for inhibiting acid secretion.[citation needed] Because the H,K-ATPase is the final step of acid secretion, an inhibitor of this enzyme is more effective...
    55 KB (6,038 words) - 15:00, 12 April 2024
  • Thumbnail for Acetylcholinesterase inhibitor
    Acetylcholinesterase inhibitors (AChEIs) also often called cholinesterase inhibitors, inhibit the enzyme acetylcholinesterase from breaking down the neurotransmitter...
    26 KB (2,384 words) - 06:59, 23 February 2024
  • 1948. NSAIDs work by inhibiting the activity of cyclooxygenase enzymes (the COX-1 and COX-2 isoenzymes). In cells, these enzymes are involved in the synthesis...
    100 KB (10,821 words) - 19:42, 23 April 2024
  • Thumbnail for Cholesterol side-chain cleavage enzyme
    side-chain cleavage enzyme is commonly referred to as P450scc, where "scc" is an acronym for side-chain cleavage. P450scc is a mitochondrial enzyme that catalyzes...
    24 KB (2,657 words) - 13:17, 24 January 2024
  • antagonist, is a medication which functions as a leukotriene-related enzyme inhibitor (arachidonate 5-lipoxygenase) or leukotriene receptor antagonist (cysteinyl...
    10 KB (1,070 words) - 02:56, 18 April 2024
  • Thumbnail for Cholinesterase inhibitor
    stimulating the muscarinic receptor, for example pilocarpine, or by inhibiting the enzyme acetylcholinesterase, which hydrolyses the acetylcholine in the...
    13 KB (1,105 words) - 19:32, 1 March 2024
  • Thumbnail for Ramipril
    Ramipril (category ACE inhibitors)
    positive Zn+2 to inhibit the ACE enzyme. The COOH helps orient it with the enzyme. Ramipril is similar in structure to another ACE Inhibitor, trandolapril...
    17 KB (1,693 words) - 01:07, 23 April 2024
  • Thumbnail for PDE5 inhibitor
    A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase...
    16 KB (1,721 words) - 14:51, 11 March 2024
  • Thumbnail for Alpha-1 antitrypsin
    gene. A protease inhibitor, it is also known as alpha1–proteinase inhibitor (A1PI) or alpha1-antiproteinase (A1AP) because it inhibits various proteases...
    32 KB (3,335 words) - 07:02, 1 April 2024
  • angiotensin converting enzyme (ACE) inhibitors in regulating blood pressure. This led to the development of captopril, the first ACE inhibitor. When the adverse...
    27 KB (3,407 words) - 10:03, 9 July 2023
  • Thumbnail for Alpha-Arbutin
    Alpha-Arbutin (category Enzyme inhibitors)
    the α-anomer of arbutin (β-arbutin), and like the β-form it is an enzyme inhibitor of human tyrosinase. α-Arbutin is used in the cosmetic and pharmaceutical...
    10 KB (779 words) - 11:28, 29 March 2024
  • Thumbnail for Mixed inhibition
    Mixed inhibition (category Enzyme inhibitors)
    Mixed inhibition is a type of enzyme inhibition in which the inhibitor may bind to the enzyme whether or not the enzyme has already bound the substrate...
    8 KB (1,062 words) - 07:12, 27 March 2022
  • Thumbnail for Dihydrofolate reductase inhibitor
    A dihydrofolate reductase inhibitor (DHFR inhibitor) is a molecule that inhibits the function of dihydrofolate reductase, and is a type of antifolate....
    4 KB (406 words) - 05:06, 3 December 2023
  • Thumbnail for Dopaminergic
    synapses with dopamine receptors in them may also be labeled as dopaminergic. Enzymes that regulate the biosynthesis or metabolism of dopamine such as aromatic...
    11 KB (1,161 words) - 08:42, 28 January 2024