• Thumbnail for FGF10
    Fibroblast growth factor 10 is a protein that in humans is encoded by the FGF10 gene. The protein encoded by this gene is a member of the fibroblast growth...
    11 KB (1,338 words) - 10:26, 25 April 2024
  • Thumbnail for Apical ectodermal ridge
    lateral mesoderm, restricting the expression of FGF10 through intermediate Wnt signals. Then, FGF10 in the lateral plate mesoderm signals to the surface...
    25 KB (3,322 words) - 04:08, 11 April 2024
  • Thumbnail for Lateral plate mesoderm
    secretes FGF8 and FGF4 which maintains the FGF10 signal and induces proliferation in the mesoderm. The position of FGF10 expression is regulated by Wnt8c in...
    6 KB (674 words) - 00:41, 31 July 2023
  • mesoderm. WNT2B and WNT8C stabilize this FGF10 expression in the forelimb and hindlimb, respectively. This FGF10 expression stimulates WNT3 expression in...
    24 KB (2,940 words) - 22:31, 13 January 2024
  • Thumbnail for Limb development
    and FGF4 which maintain the FGF10 signal and induce proliferation in the mesoderm.[citation needed] The position of FGF10 expression is regulated by two...
    36 KB (4,214 words) - 21:12, 30 April 2024
  • Thumbnail for Paracrine signaling
    produce Fgf10. Fgf10 then signals to the ectoderm to begin production of Fgf8, which also stimulates the production of Fgf10. Deletion of Fgf10 results...
    46 KB (4,940 words) - 22:55, 3 December 2023
  • complex and regulated by a variety of mechanisms in a tissue specific manner. FGF10 is also known as "keratinocyte growth factor 2". Palifermin Rotolo S, Ceccarelli...
    2 KB (182 words) - 00:56, 11 June 2023
  • Thumbnail for Chronic obstructive pulmonary disease
    COPD. A genetic association for the variants has been sometimes found with FGF10. Alcohol abuse can lead to alcoholic lung disease and is seen to be an independent...
    157 KB (17,022 words) - 03:53, 30 April 2024
  • Thumbnail for Apert syndrome
    Lana-Elola E, Rice DP, Sharpe J, Dickson C (February 2009). "Evidence that Fgf10 contributes to the skeletal and visceral defects of an Apert syndrome mouse...
    21 KB (2,523 words) - 03:08, 16 October 2023
  • factor 8(FGF8) Fibroblast growth factor 9(FGF9) Fibroblast growth factor 10(FGF10) Fibroblast growth factor 11(FGF11) Fibroblast growth factor 12(FGF12) Fibroblast...
    10 KB (1,131 words) - 19:14, 31 March 2024
  • which are structurally related signaling molecules: Members FGF1 through FGF10 all bind fibroblast growth factor receptors (FGFRs). FGF1 is also known...
    25 KB (3,123 words) - 20:10, 26 April 2024
  • Thumbnail for Lung
    fibroblast growth factors FGF10 and FGFR2b, and bone morphogenetic protein BMP4. FGF10 is seen to have the most prominent role. FGF10 is a paracrine signalling...
    104 KB (11,656 words) - 04:16, 20 March 2024
  • Thumbnail for Turtle
    signaled locally by proteins known as fibroblast growth factors that include FGF10. The shoulder girdle in turtles is made up of two bones, the scapula and...
    126 KB (13,068 words) - 02:12, 26 April 2024
  • Thumbnail for Cleft lip and cleft palate
    by research on animal models, including of the genes BMP4, SHH, SHOX2, FGF10 and MSX1. Environmental influences may also cause, or interact with genetics...
    94 KB (10,403 words) - 22:13, 14 April 2024
  • in the body is demonstrated in response to the signaling of the ramogen FGF10, serving as an inhibitor of branching. The following table is a list of...
    5 KB (656 words) - 21:04, 4 February 2023
  • Thumbnail for Cereblon
    levels of fibroblast growth factor 8 (FGF8) and fibroblast growth factor 10 (FGF10). FGF8 in turn regulates a number of developmental processes, such as limb...
    12 KB (1,350 words) - 18:12, 22 April 2024
  • Thumbnail for Turtle shell
    development is signalled locally by fibroblast growth factors including FGF10. Zoologists have sought to explain the evolutionary origin of the turtles...
    43 KB (4,747 words) - 17:53, 22 February 2024
  • Thumbnail for List of distinct cell types in the adult human body
    unknown brain None None unknown None COL22A1, LOC401134, NPFFR2 Exc L5 THEMIS FGF10 unknown unknown brain None None unknown None BDNF, CRH, NPFFR2 Exc L5 THEMIS...
    171 KB (1,179 words) - 08:07, 28 April 2024
  • HGNC:3685 P21781 5638 FGF8 HGNC:3686 P55075 5639 FGF9 HGNC:3687 P31371 5640 FGF10 HGNC:3666 O15520 5641 FGF11 HGNC:3667 Q92914 5642 FGF12 HGNC:3668 P61328...
    277 KB (17 words) - 23:17, 27 April 2024
  • Thumbnail for Fibroblast growth factor receptor 1
    activate one or more of the FGFRs: FGF1 to FGF10 and FGF16 to FGF23. Fourteen of these, FGF1 to FGF6, FGF8, FGF10, FGF17, and FGF19 to FGF23 bind and activate...
    44 KB (5,001 words) - 17:06, 4 January 2024
  • cell proliferation and differentiation, fibroblast growth factors Fgf7 and Fgf10 that initiate TEC expansion, TNFT, CD40, lymfotoxin β receptor (LTβR) and...
    11 KB (1,409 words) - 17:32, 6 April 2024
  • Thumbnail for TBX5 (gene)
    early development of the forelimb by triggering fibroblast growth factor, FGF10. TBX5 is a transcription factor that codes for the protein called T-box...
    21 KB (2,467 words) - 22:17, 30 March 2024
  • Thumbnail for Notch signaling pathway
    10460. PMID 14699589. Norgaard GA, Jensen JN, Jensen J (December 2003). "FGF10 signaling maintains the pancreatic progenitor cell state revealing a novel...
    87 KB (10,149 words) - 00:21, 27 April 2024
  • Thumbnail for Fibroblast growth factor receptor 2
    Lana-Elola E, Rice DP, Sharpe J, Dickson C (Feb 2009). "Evidence that Fgf10 contributes to the skeletal and visceral defects of an Apert syndrome mouse...
    14 KB (1,748 words) - 14:34, 11 December 2023
  • Thumbnail for Bat flight
    crucial in developmental and evolutionary elongation of bat forelimb digits.FGF10 signaling is also likely required for the development of bat wing membrane...
    22 KB (2,790 words) - 04:48, 14 March 2024
  • Thumbnail for Otic vesicle
    BMP signals help control patterning in the early otic vesicle. Fgf3 and Fgf10 are suggested to play a role in otic induction in mice, as were Msx genes...
    7 KB (814 words) - 10:54, 16 April 2024
  • Thumbnail for Schmitt Gillenwater Kelly syndrome
    binding to the Patched receptor, and directly activating BMP2, Fgf10, Wnt5a, and BMP4. Fgf10 induces further Shh expression, while BMP4 represses Wnt5a expression...
    12 KB (1,084 words) - 21:20, 6 January 2024
  • Thumbnail for Cereblon E3 ligase modulator
    substrates and downregulation of fibroblast growth factor 8 (FGF8) and FGF10. This disrupts the positive feedback loop between the two growth factors...
    49 KB (5,487 words) - 11:41, 24 January 2024
  • Thumbnail for Sp8 transcription factor
    distal limb structures. Sp8 and Sp9 mediate Fgf10 signaling, which in turn regulates Fgf8 expression (Fgf10→Fgf8). Fgf8 is essential for normal limb development...
    7 KB (936 words) - 23:10, 4 April 2024
  • by gene regulatory networks and signalling pathways, exemplified by the FGF10 gene. Retrospective clonal analysis complemented their work on the SHF and...
    16 KB (1,578 words) - 21:01, 8 November 2023