• Thumbnail for Factor IX
    Factor IX (or Christmas factor) (EC 3.4.21.22) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1. Deficiency...
    31 KB (1,942 words) - 05:42, 7 April 2024
  • Thumbnail for Haemophilia B
    inherited mutation of the gene for factor IX, and resulting in a deficiency of factor IX. It is less common than factor VIII deficiency (haemophilia A)....
    17 KB (1,908 words) - 19:11, 17 December 2023
  • known as factor IX complex, sold under the brand name Kcentra among others, is a combination medication made up of blood clotting factors II, IX, and X...
    16 KB (1,288 words) - 04:40, 13 April 2024
  • Thumbnail for Coagulation
    Willebrand factor (vWF), which is released from the endothelium and from platelets; vWF forms additional links between the platelets' glycoprotein Ib/IX/V and...
    61 KB (5,960 words) - 15:41, 29 April 2024
  • Thumbnail for Factor X
    Factor X is synthesized in the liver and requires vitamin K for its synthesis. Factor X is activated, by hydrolysis, into factor Xa by both factor IX...
    27 KB (3,302 words) - 09:03, 10 March 2024
  • Thumbnail for Factor VIII
    Willebrand factor. The active protein (sometimes written as coagulation factor VIIIa) interacts with another coagulation factor called factor IX. This interaction...
    17 KB (2,029 words) - 09:54, 27 April 2024
  • gene for clotting Factor IX. The gene is expressed in the liver to produce Factor IX protein, to increase blood levels of Factor IX and thereby limit...
    11 KB (784 words) - 11:53, 8 March 2024
  • Thumbnail for Coagulation factor VII
    coagulation factor VII), which in turn activates factor IX and factor X. Using genetic recombination a recombinant factor VIIa (eptacog alfa) (trade names include...
    12 KB (1,382 words) - 16:52, 23 April 2024
  • Thumbnail for Haemophilia
    occurs due to low amounts of clotting factor VIII, and haemophilia B, which occurs due to low levels of clotting factor IX. They are typically inherited from...
    60 KB (6,663 words) - 13:06, 21 April 2024
  • Thumbnail for Factor XI
    prekallikrein, factor XII, factor XI, and factor IX). Factor XIa activates factor IX by selectively cleaving arg-ala and arg-val peptide bonds. Factor IXa, in...
    17 KB (2,026 words) - 12:11, 8 March 2024
  • deficient in Factor II, Factor VII, Factor IX, and Factor X. Aged plasma is deficient in Factor V & Factor VIIIC. Serum is deficient in factors I, V & VIIIC...
    13 KB (1,474 words) - 15:30, 26 March 2024
  • adeno-associated virus used for the treatment of Hemophilia B (congenital Factor IX deficiency). It was approved for medical use in Canada in December 2023...
    13 KB (752 words) - 02:37, 30 April 2024
  • Thumbnail for EGF-like domain
    activity or deficiency of blood coagulation factor IX. Point mutations resulting in decreased affinity of factor IX to calcium are thought to be implicated...
    25 KB (3,071 words) - 21:41, 10 September 2022
  • Thumbnail for Emicizumab
    activated coagulation factor IX and to factor X, mediating the activation of the latter. This is normally the function of coagulation factor VIII, which is missing...
    6 KB (411 words) - 20:32, 31 January 2024
  • Thumbnail for Biotechnology in pharmaceutical manufacturing
    sequence of the RNA for Factor IX by examining the amino acids in Factor IX: Microsequencing of highly purified... [Factor IX] yielded sufficient amino...
    14 KB (1,536 words) - 02:07, 9 December 2023
  • human diseases. The protein in question was the human blood clotting factor IX. Another difference from Dolly the Sheep was the source cell type of the...
    7 KB (888 words) - 02:07, 2 December 2023
  • Intrinsic tenase complex contains the active factor IX (IXa), its cofactor factor VIII (VIIIa), the substrate (factor X), and they are activated by negatively...
    1 KB (156 words) - 17:00, 8 February 2022
  • F9 (redirect from F.IX)
    Financial Reporting, a financial reporting software application Factor IX, a coagulation factor F9, a function key on a computer keyboard Zeolite F-9, a sodium-type...
    2 KB (229 words) - 19:06, 4 January 2024
  • hemophilia by cloning the canine Factor IX gene. She also identified the mutations responsible for several Factor VII and Factor X-deficient blood clotting...
    15 KB (1,439 words) - 17:58, 10 January 2024
  • Thumbnail for Haemophilia A
    levels of active clotting factor. Two of the most common differential diagnoses are haemophilia B which is a deficiency in Factor IX and von Willebrand Disease...
    22 KB (2,420 words) - 22:16, 10 January 2024
  • Thumbnail for CSL Limited
    factor VIII concentrate Berinin P, freeze-dried human coagulation factor IX concentrate Factor X P Behring, a freeze-dried human coagulation factor IX...
    30 KB (2,888 words) - 09:54, 3 March 2024
  • Thumbnail for X-linked recessive inheritance
    clotting disorder caused by a mutation of the Factor IX gene and leading to a deficiency of Factor IX. It is rarer than hemophilia A. As noted above...
    15 KB (1,754 words) - 18:07, 28 February 2024
  • Thumbnail for Tissue factor
    activated factor IX and factor VIII. Both pathways lead to the activation of factor X (the common pathway), which combines with activated factor V in the...
    15 KB (1,828 words) - 10:30, 27 April 2024
  • Thumbnail for Adeno-associated virus
    Herzog RW (January 2014). "Role of the vector genome and underlying factor IX mutation in immune responses to AAV gene therapy for hemophilia B". Journal...
    73 KB (8,636 words) - 15:36, 6 April 2024
  • Thumbnail for Bleeding
    deficiency of Factor VIII causes classic hemophilia A while deficiencies of Factor IX cause "Christmas disease"(hemophilia B). Antibodies to Factor VIII can...
    22 KB (2,409 words) - 00:06, 1 April 2024
  • Thumbnail for Title IX
    TitleĀ IX is the most commonly used name for the landmark federal civil rights law in the United States that was enacted as part (Title IX) of the Education...
    94 KB (9,435 words) - 15:01, 25 April 2024
  • Thumbnail for Thrombophilia
    factor from damaged tissue. Tissue factor binds to circulating factor VIIa. The combination activates factor X to factor Xa and factor IX to factor IXa...
    43 KB (5,067 words) - 17:24, 19 January 2024
  • Thumbnail for Contaminated blood scandal in the United Kingdom
    HIV, as a result of receiving contaminated blood or contaminated clotting factor products. Many of the products were imported from the US, and distributed...
    45 KB (4,751 words) - 10:55, 29 April 2024
  • adeno-associated viral vector which is designed to transfer a working copy of the Factor IX gene into the livers of patients who carry non-functioning copies. In...
    10 KB (904 words) - 17:58, 10 January 2024
  • Thumbnail for Grand Duchess Anastasia Nikolaevna of Russia
    dealing with the controversy surrounding Anastasia's death. Hemophilia B (Factor IX Deficiency) Could the Bulgarian mountain village of Gabarevo be the last...
    53 KB (6,609 words) - 05:31, 20 April 2024