• Thumbnail for Factor VIII
    Coagulation factor VIII (Factor VIII, FVIII) is an essential blood-clotting protein, also known as anti-hemophilic factor (AHF). In humans, factor VIII is encoded...
    17 KB (2,029 words) - 09:54, 27 April 2024
  • Thumbnail for Factor VIII (medication)
    Factor VIII is a medication used to treat and prevent bleeding in people with hemophilia A and other causes of low factor VIII. Certain preparations may...
    13 KB (818 words) - 03:25, 20 April 2024
  • Thumbnail for Haemophilia A
    a blood clotting disorder caused by a genetic deficiency in clotting factor VIII, thereby resulting in significant susceptibility to bleeding, both internally...
    22 KB (2,420 words) - 22:16, 10 January 2024
  • Thumbnail for Von Willebrand factor
    function; elements of note are: the D'/D3 domain, which binds to factor VIII (von Willebrand factor type D domain). the A1 domain, which binds to: platelet GPIb-receptor...
    17 KB (2,069 words) - 05:08, 4 January 2024
  • Thumbnail for Coagulation
    best-known coagulation factor disorders are the hemophilias. The three main forms are hemophilia A (factor VIII deficiency), hemophilia B (factor IX deficiency...
    62 KB (6,077 words) - 12:17, 28 April 2024
  • Thumbnail for Haemophilia
    occurs due to low amounts of clotting factor VIII, and haemophilia B, which occurs due to low levels of clotting factor IX. They are typically inherited from...
    60 KB (6,663 words) - 13:06, 21 April 2024
  • Thumbnail for Contaminated blood scandal in the United Kingdom
    haemophilia were principally infected via the plasma-derived product known as factor VIII, a processed pharmaceutical product sourced from the United States and...
    45 KB (4,748 words) - 14:59, 27 April 2024
  • Thumbnail for Haemophilia B
    inherited mutation of the gene for factor IX, and resulting in a deficiency of factor IX. It is less common than factor VIII deficiency (haemophilia A). Haemophilia...
    17 KB (1,908 words) - 19:11, 17 December 2023
  • Thumbnail for Von Willebrand disease
    agglutination (RIPA) assays. Factor VIII levels are also performed because factor VIII is bound to VWF which protects the factor VIII from rapid breakdown within...
    43 KB (5,267 words) - 10:19, 27 April 2024
  • Thumbnail for Factor X
    factor IX (with its cofactor, factor VIII in a complex known as intrinsic tenase) and factor VII with its cofactor, tissue factor (a complex known as extrinsic...
    27 KB (3,302 words) - 09:03, 10 March 2024
  • Thumbnail for Bayer
    Along with the purchase of Cutter, Bayer acquired Cutter's Factor VIII business. Factor VIII, a clotting agent used to treat hemophilia, was produced,...
    119 KB (11,418 words) - 15:10, 21 April 2024
  • against coagulation factor VIII. These autoantibodies constitute the most common spontaneous inhibitor to any coagulation factor and may induce spontaneous...
    10 KB (1,468 words) - 18:35, 1 October 2022
  • is factor VIII (also called antihaemophilic factor or AHF), which is why cryoprecipitate is sometimes called cryoprecipitated antihaemophilic factor or...
    8 KB (745 words) - 22:11, 27 November 2023
  • made of a virus (AAV5) that has been modified to contain the gene for factor VIII, which is lacking in people with hemophilia A. It is an adeno-associated...
    17 KB (1,233 words) - 06:25, 18 December 2023
  • 1985. Hemophilia A causes a deficiency in Factor VIII, a protein required for blood clotting. Factor VIII injections are a common treatment to prevent...
    26 KB (3,366 words) - 03:03, 30 January 2024
  • is a medication used for the treatment of hemophilia A (congenital factor VIII deficiency). Efanesoctocog alfa was approved for medical use in the United...
    6 KB (300 words) - 02:40, 27 April 2024
  • Thumbnail for Recombinant DNA
    factor VIII, a blood-clotting protein that is administered to patients with the bleeding disorder hemophilia, who are unable to produce factor VIII in...
    35 KB (3,893 words) - 18:47, 27 March 2024
  • factor. If the patient has a high titer antibody against factor VIII, try porcine factor VIII or prothrombin complex concentrates to stop the bleeding...
    13 KB (1,474 words) - 15:30, 26 March 2024
  • Thumbnail for Bleeding
    deficiency of Factor VIII causes classic hemophilia A while deficiencies of Factor IX cause "Christmas disease"(hemophilia B). Antibodies to Factor VIII can also...
    22 KB (2,409 words) - 00:06, 1 April 2024
  • Thumbnail for Emicizumab
    coagulation factor IX and to factor X, mediating the activation of the latter. This is normally the function of coagulation factor VIII, which is missing...
    6 KB (411 words) - 20:32, 31 January 2024
  • Thumbnail for Factor IX
    into factor IXa, in the presence of Ca2+, membrane phospholipids, and a Factor VIII cofactor, it hydrolyses one arginine-isoleucine bond in factor X to...
    31 KB (1,942 words) - 05:42, 7 April 2024
  • Thumbnail for Partial thromboplastin time
    following coagulation factors: I (fibrinogen), II (prothrombin), V (proaccelerin), VIII (anti-hemophilic factor), X (Stuart–Prower factor), XI (plasma thromboplastin...
    9 KB (954 words) - 04:40, 9 April 2024
  • Thumbnail for Thrombophilia
    associated with reduced levels of von Willebrand factor – because of increased clearance – and factor VIII, which is related to thrombotic risk . A number...
    43 KB (5,067 words) - 17:24, 19 January 2024
  • Thumbnail for Ryan White
    As a haemophiliac, he became infected with HIV from a contaminated factor VIII blood treatment and, when diagnosed in December 1984, was given six months...
    39 KB (4,484 words) - 13:21, 23 April 2024
  • Recombinant factor VIIa, which is an activated form of factor VII, bypasses factors VIII and IX and causes coagulation without the need for factors VIII and IX...
    19 KB (1,756 words) - 15:27, 27 January 2024
  • HIV-infected infusions of Factor VIII. Ricky, Robert, and Randy were hemophiliacs who contracted HIV from infusions of Factor VIII when they were less than...
    9 KB (784 words) - 01:16, 9 April 2024
  • recombinant coagulation factor VIII since it has an amino acid sequence which compares to the 90 + 80 kDa form of factor VIII (BDDrFVIII). It also has...
    8 KB (547 words) - 19:59, 20 December 2023
  • Intrinsic tenase complex contains the active factor IX (IXa), its cofactor factor VIII (VIIIa), the substrate (factor X), and they are activated by negatively...
    1 KB (156 words) - 17:00, 8 February 2022
  • list of Alboran Sea; see List of NATO country codes A brand name of factor VIII (medication) Y8 (disambiguation) This disambiguation page lists articles...
    334 bytes (85 words) - 08:35, 7 March 2024
  • Thumbnail for CSL Limited
    factor VIII concentrate Berinin P, freeze-dried human coagulation factor IX concentrate Factor X P Behring, a freeze-dried human coagulation factor IX...
    30 KB (2,888 words) - 09:54, 3 March 2024