GTP cyclohydrolase I (GTPCH) (EC 3.5.4.16) is a member of the GTP cyclohydrolase family of enzymes. GTPCH is part of the folate and biopterin biosynthesis...
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toxoflavin. Several GTP cyclohydrolases exist, which sometimes synthesize different products for different pruposes: GTP cyclohydrolase I, part of the tetrahydrobiopterin...
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Autosomal dominant GTP cyclohydrolase I deficiency (AD-GTPCHD) is a disease caused by dysfunction of GTP cyclohydrolase I, an enzyme that plays an important...
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recessive GTP cyclohydrolase I deficiency (AR-GTPCHD) is a disorder associated with the deficient operation of the enzyme GTP cyclohydrolase I. The condition...
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Autosomal dominant GTP cyclohydrolase I deficiency (autosomal dominant Segawa syndrome) Autosomal recessive GTP cyclohydrolase I deficiency Tyrosine...
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Princely Heritage Grey Coat Hospital, a secondary school in London GTP cyclohydrolase I, an enzyme Gym Class Heroes, an American band Knight Grand Cross...
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GTP cyclohydrolase 1 feedback regulatory protein is an enzyme that in humans is encoded by the GCHFR gene. GTP cyclohydrolase I feedback regulatory protein...
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polymorphisms in GCH1 (GTP cyclohydrolase I) and ChAT (choline acetyltransferase) affect AD susceptibility in East Asians. GTP cyclohydrolase I is an enzyme that...
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Sapropterin is indicated in tetrahydrobiopterin deficiency caused by GTP cyclohydrolase I (GTPCH) deficiency, or 6-pyruvoyltetrahydropterin synthase (PTPS)...
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Yanofsky C (1992). "The mtrAB operon of Bacillus subtilis encodes GTP cyclohydrolase I (MtrA), an enzyme involved in folic acid biosynthesis, and MtrB,...
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Category:EC 3.5.4 (In cyclic amidines) Adenosine deaminase (EC 3.5.4.4) GTP cyclohydrolase I (EC 3.5.4.16) Category:EC 3.5.5 (In nitriles) Nitrilase (EC 3.5.5...
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in dopamine synthesis and transport: Tyrosine hydroxylase (TH), GTP Cyclohydrolase I (GTPCH), and Vesicular Monoamine Transporter (VMAT) in Drosophila...
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translationally. All known folE RNAs are present upstream of genes encoding GTP cyclohydrolase I, which performs a step in folate metabolism. folE RNAs have been...
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pathway, GTP is converted to 7,8-dihydroneopterin triphosphate by GTP cyclohydrolase I (GTPCH-1, FolE), which expands the imidazole ring in GTP by one carbon...
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PMID 1883349. Thöny B, Heizmann CW, Mattei MG (March 1995). "Human GTP-cyclohydrolase I gene and sepiapterin reductase gene map to region 14q21-q22 and 2p14-p12...
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Retrieved 2018-03-09. Thöny B, Blau N (1997). "Mutations in the GTP cyclohydrolase I and 6-pyruvoyl-tetrahydropterin synthase genes". Human Mutation....
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Swick L, Kapatos G (2006). "A yeast 2-hybrid analysis of human GTP cyclohydrolase I protein interactions". J. Neurochem. 97 (5): 1447–55. doi:10.1111/j...
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the thesis labelled "The relationship of gene variation encoding GTP cyclohydrolase with the function of vascular endothelium in patients with type 2...
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Swick L, Kapatos G (2006). "A yeast 2-hybrid analysis of human GTP cyclohydrolase I protein interactions". J. Neurochem. 97 (5): 1447–55. doi:10.1111/j...
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hydrolysis of GTP by GTP cyclohydrolase II. Alternatively two separate enzymes can carry out this reaction, initially GTP cyclohydrolase IIa hydrolyses...
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Swick L, Kapatos G (2006). "A yeast 2-hybrid analysis of human GTP cyclohydrolase I protein interactions". J. Neurochem. 97 (5): 1447–55. doi:10.1111/j...
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x. PMID 3536512. Thöny B, Heizmann CW, Mattei MG (1995). "Human GTP-cyclohydrolase I gene and sepiapterin reductase gene map to region 14q21-q22 and 2p14-p12...
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(1995). "Identification of a rabphilin-3A-interacting protein as GTP cyclohydrolase I in PC12 cells". Biochem. Biophys. Res. Commun. 205 (2): 1409–16....
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are necessary for dopamine synthesis, such as tyrosine hydroxylase, GTP cyclohydrolase 1 and AADC. A symptomatic approach is a treatment focused on the symptoms...
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Retrieved 16 June 2019. Thöny B; Blau N (1997). "Mutations in the GTP cyclohydrolase I and 6-pyruvoyl-tetrahydropterin synthase genes". Hum. Mutat. 10 (1):...
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1159/000163662. PMID 1883524. Thöny B, Blau N (1997). "Mutations in the GTP cyclohydrolase I and 6-pyruvoyl-tetrahydropterin synthase genes". Hum. Mutat. 10 (1):...
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in the riboflavin biosynthesis pathway. It is formed from GTP by the enzyme GTP cyclohydrolase IIa which catalyzes the hydrolysis of the 8,9 bond in the...
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Neopterin (category Articles without InChI source)
occurs in two steps from guanosine triphosphate (GTP). The first being catalyzed by GTP cyclohydrolase, which opens the ribose group. Phosphatases next...
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List of EC numbers (EC 3) (section 3.6.5: Acting on GTP to facilitate cellular and subcellular movement)
4.16: GTP cyclohydrolase I EC 3.5.4.17: adenosine-phosphate deaminase EC 3.5.4.18: ATP deaminase EC 3.5.4.19: phosphoribosyl-AMP cyclohydrolase EC 3.5...
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aromatic amino acid dopa decarboxylase, tyrosine hydroxylase and GTP-cyclohydrolase 1, to the striatum in the brain, reprogramming transduced cells to...
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