Gabaa may refer to: Gabâ, the concept of divine retribution in parts of the Philippines GABAA may refer to: GABAA receptor Gaaba, an Indian dish prepared... 322 bytes (64 words) - 17:29, 17 April 2018 |
GABA receptor (section GABAA receptor) central nervous system. There are two classes of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels (also known as ionotropic... 35 KB (3,884 words) - 16:49, 26 April 2024 |
Alcohol intoxication (section GABAA receptors) neurotransmitter systems with enhanced functions are: GABAA, 5-HT3 receptor agonism (responsible for GABAergic (GABAA receptor PAM), glycinergic, and cholinergic... 60 KB (6,025 words) - 11:45, 5 May 2024 |
In pharmacology, GABAA receptor positive allosteric modulators, also known as GABAkines or GABAA receptor potentiators, are positive allosteric modulator... 31 KB (3,523 words) - 16:44, 26 April 2024 |
GABA receptor antagonist (redirect from GABAA receptor antagonist) securinine and metrazol, and the benzodiazepine GABAA receptor antagonist flumazenil. Other agents which may have GABAA receptor antagonism include the antibiotic... 3 KB (315 words) - 21:55, 14 April 2024 |
Muscimol (category GABAA receptor agonists) mushroom. Muscimol is a potent and selective orthosteric agonist for the GABAA receptor and displays sedative-hypnotic, depressant and hallucinogenic psychoactivity... 26 KB (2,462 words) - 16:42, 28 April 2024 |
The GABAA-rho receptor (previously known as the GABAC receptor) is a subclass of GABAA receptors composed entirely of rho (ρ) subunits. GABAA receptors... 16 KB (1,639 words) - 05:16, 7 November 2023 |
Zolpidem (category GABAA receptor positive allosteric modulators) is a GABAA receptor agonist of the imidazopyridine class. It works by increasing GABA effects in the central nervous system by binding to GABAA receptors... 58 KB (5,813 words) - 02:36, 8 May 2024 |
Γ-Aminobutyric acid (category GABAA receptor positive allosteric modulators) GABA is γ-aminobutyrate. Two general classes of GABA receptor are known: GABAA in which the receptor is part of a ligand-gated ion channel complex GABAB... 51 KB (5,563 words) - 23:57, 21 March 2024 |
Propofol (category GABAA receptor positive allosteric modulators) mechanisms of action, both through potentiation of GABAA receptor activity and therefore acting as a GABAA receptor positive allosteric modulator, thereby... 56 KB (5,515 words) - 20:45, 6 May 2024 |
Allopregnanolone (category GABAA receptor positive allosteric modulators) It is a neurosteroid and acts as a positive allosteric modulator of the GABAA receptor, the major biological target of the inhibitory neurotransmitter... 50 KB (4,804 words) - 11:18, 26 January 2024 |
Bromazolam (category GABAA receptor positive allosteric modulators) Bromazolam is a non subtype selective agonist at the benzodiazepine site of GABAA receptors, with a binding affinity of 2.81 nM at the α1 subtype, 0.69 nM... 20 KB (2,075 words) - 18:54, 16 April 2024 |
GABA receptor agonist (section GABAA) the brain, binding to GABA receptors and inhibiting neuronal signaling. GABAA receptor ligands include: Abecarnil Barbiturates (in high doses) Etomidate... 8 KB (740 words) - 19:39, 11 March 2024 |
brand names in parentheses. EVT-201 – GABAA receptor positive allosteric modulator[1] Lorediplon (GF-015535-00) – GABAA receptor positive allosteric modulator... 4 KB (205 words) - 09:27, 26 February 2024 |
A GABAA receptor negative allosteric modulator is a negative allosteric modulator (NAM), or inhibitor, of the GABAA receptor, a ligand-gated ion channel... 10 KB (934 words) - 07:32, 16 September 2023 |
Alpidem (category GABAA receptor positive allosteric modulators) imidazopyridine family, structurally related to the Z-drug zolpidem, and acts as a GABAA receptor positive allosteric modulator of the benzodiazepine site of the... 49 KB (4,669 words) - 06:29, 5 January 2024 |
are positive allosteric modulators of the GABA type A receptors (GABAA). The GABAA receptors are ligand-gated chloride-selective ion channels that are... 102 KB (9,983 words) - 06:18, 15 May 2024 |
acid) – constituent of valerian; has anticonvulsant effects; PAM of the GABAA receptor Derivatives: isovalerate (isopentanoate/3-methylbutanoate), menthyl... 8 KB (754 words) - 04:40, 27 January 2024 |
Darigabat (category GABAA receptor positive allosteric modulators) α2, α3, and α5 subunit-containing GABAA receptors, with minimal functional activity at α1 subunit-containing GABAA receptors. A dose of darigabat that... 8 KB (552 words) - 02:18, 28 February 2024 |
MRK-409, also known as MK-0343, is a GABAA receptor partial agonist. It was designed to be a non-sedative anxiolytic, however its development was halted... 4 KB (319 words) - 15:54, 30 March 2024 |
Flumazenil (category GABAA receptor negative allosteric modulators) Flumazenil (also known as flumazepil, code name Ro 15-1788) is a selective GABAA receptor antagonist administered via injection, otic insertion, or intranasally... 23 KB (2,416 words) - 16:54, 24 March 2024 |
QH-ii-066 is a highly subtype-selective GABAA agonist which was designed to bind selectively to the α5 subtype of GABAA receptors. The α5 subtype (and to a... 6 KB (574 words) - 09:29, 23 March 2024 |
Menthol (category GABAA receptor positive allosteric modulators) activity that may stimulate muscles. Some studies show that menthol acts as a GABAA receptor positive allosteric modulator and increases GABAergic transmission... 30 KB (2,865 words) - 21:48, 2 May 2024 |
Thiocolchicoside (category GABAA receptor agonists) receptors (nAchRs). However, it also appears to be a competitive antagonist of GABAA and glycine receptors. As such, it has powerful convulsant activity and... 14 KB (1,272 words) - 17:58, 20 April 2024 |