• Thumbnail for Genetically modified mouse
    A genetically modified mouse or genetically engineered mouse model (GEMM) is a mouse (Mus musculus) that has had its genome altered through the use of...
    14 KB (1,707 words) - 10:40, 24 January 2024
  • A knockout mouse, or knock-out mouse, is a genetically modified mouse (Mus musculus) in which researchers have inactivated, or "knocked out", an existing...
    15 KB (1,889 words) - 22:25, 7 November 2023
  • Thumbnail for Genetically modified organism
    A genetically modified organism (GMO) is any organism whose genetic material has been altered using genetic engineering techniques. The exact definition...
    222 KB (24,519 words) - 00:52, 14 April 2024
  • A humanized mouse is a genetically modified mouse that has functioning human genes, cells, tissues and/or organs. Humanized mice are commonly used as...
    30 KB (3,634 words) - 10:39, 24 January 2024
  • Thumbnail for History of genetic engineering
    genetically modified animal was a mouse created in 1974 by Rudolf Jaenisch. In 1976 the technology was commercialised, with the advent of genetically...
    58 KB (6,333 words) - 16:30, 24 March 2024
  • Thumbnail for Genetic engineering
    genetically modified if its genetic material has been altered through any method, including conventional breeding. A 'GMO' is a genetically modified organism...
    134 KB (14,196 words) - 05:24, 16 April 2024
  • Thumbnail for Mouse
    knockout mouse is a genetically modified mouse that has had one or more of its genes made inoperable through a gene knockout. Experimental mouse model systems...
    16 KB (1,765 words) - 11:35, 13 March 2024
  • Thumbnail for Genetically modified animal
    Genetically modified animals are animals that have been genetically modified for a variety of purposes including producing drugs, enhancing yields, increasing...
    102 KB (11,046 words) - 07:55, 25 April 2024
  • Thumbnail for Genetically modified mammal
    Genetically modified mammals are mammals that have been genetically engineered. They are an important category of genetically modified organisms. The majority...
    18 KB (1,844 words) - 11:30, 13 August 2023
  • Transgene (category Genetic engineering)
    The two most common types of genetically modified mice are knockout mice and oncomice. Knockout mice are a type of mouse model that uses transgenic insertion...
    29 KB (3,583 words) - 02:30, 1 December 2023
  • Oncomouse (redirect from Harvard mouse)
    The OncoMouse or Harvard mouse is a type of laboratory mouse (Mus musculus) that has been genetically modified using modifications designed by Philip Leder...
    8 KB (1,034 words) - 16:03, 4 December 2023
  • Thumbnail for Dry shipper
    Dry shipper (category Genetically modified organisms)
    carry materials such as spermatozoa or preimplantation embryos of genetically modified mouse strains, safeguarding the integrity and viability of these research...
    8 KB (740 words) - 20:32, 8 November 2023
  • genetically altered mice an invention, court declares," CMAJ, Oct. 3, 2000, 163(7). CBC News, "Supreme Court rejects patent on genetically-modified mouse...
    6 KB (781 words) - 15:50, 6 November 2023
  • mice can then be bred to create transgenic lines. Transgenesis Genetically modified mouse Biology: The Unity and Diversity of Life Nanoinjection David B...
    7 KB (755 words) - 08:31, 31 December 2020
  • from genetically modified mouse that express fluorescent proteins such as green fluorescent proteins, the emission mode of OPT can yield 3D genetic expression...
    5 KB (563 words) - 11:24, 7 April 2024
  • Thumbnail for Human genetic enhancement
    is known as CRISPR/Cas-based gene therapy. Mammalian cells can be genetically modified using the straightforward, affordable, and extremely specific CRISPR/Cas...
    95 KB (10,464 words) - 20:40, 4 April 2024
  • Thumbnail for Ralph L. Brinster
    acclaimed Zadie Smith novel "White Teeth" features prominently a genetically modified mouse "Futuremouse", based loosely on the transgenic experiments of...
    35 KB (3,974 words) - 23:35, 21 February 2024
  • Thumbnail for Mammal
    and rats, are used in experiments each year. A knockout mouse is a genetically modified mouse with an inactivated gene, replaced or disrupted with an...
    212 KB (22,683 words) - 14:21, 20 April 2024
  • PEPCK-Cmus mice are genetically modified mice (Mus musculus) which as a result of their modification have up to 100 times the concentration of the PEPCK-C...
    3 KB (374 words) - 06:19, 4 December 2022
  • technologies, the company created the world’s largest repository of genetically modified mouse embryonic stem cells, known as OmniBank, and established a large-scale...
    10 KB (1,070 words) - 22:29, 3 December 2023
  • Thumbnail for Werner syndrome
    reverse the premature aging and several tissue dysfunctions in a genetically modified mouse model of the disease. Vitamin C supplementation also appeared...
    35 KB (4,341 words) - 22:19, 1 February 2024
  • Thumbnail for C57BL/6
    C57BL/6 (redirect from Inbred c57bl mouse)
    common inbred strain of laboratory mouse. It is the most widely used "genetic background" for genetically modified mice for use as models of human disease...
    8 KB (1,001 words) - 05:23, 19 November 2023
  • inserting new genetic material into a rice plant, all the descendants of the genetically modified rice plant are a strain with unique genetic information...
    12 KB (1,374 words) - 13:46, 21 January 2024
  • electric boat Rudolf Jaenisch (born 1942), Germany/U.S. – first Genetically modified mouse Alcinous Burton Jamison (1851–1938), American physician, inventor...
    108 KB (12,057 words) - 09:40, 27 April 2024
  • Thumbnail for Human uses of animals
    and rats, are used in experiments each year. A knockout mouse is a genetically modified mouse with an inactivated gene, replaced or disrupted with an...
    47 KB (4,190 words) - 16:11, 1 April 2024
  • Thumbnail for Monsanto Canada Inc v Schmeiser
    Monsanto Canada Inc v Schmeiser (category Genetically modified organisms in agriculture)
    Schmeiser's intentionally growing genetically modified plants constituted "use" of Monsanto's patented genetically modified plant cells. By a 5-4 majority...
    28 KB (3,793 words) - 04:27, 16 April 2024
  • immunodeficient mouse reconstituted with a human immune system, also generally known as humanised mouse. Although conventional mouse models have allowed...
    1 KB (131 words) - 14:50, 20 October 2022
  • was a challenge. However, in combination with RNA-seq data and genetically modified mouse models, several labeling markers, i.e. VGLUT3, TAFA4, CaV3.2,...
    11 KB (1,326 words) - 20:31, 7 November 2023
  • Thumbnail for Gene targeting
    Gene targeting (category Genetically modified organisms)
    conventional breeding (in contrast the insertion of a transgene to create a Genetically Modified Organism (GMO) could not occur naturally). However, there are exceptions...
    39 KB (4,385 words) - 10:05, 20 February 2024
  • Pinky and the Brain (category Fictional genetically engineered characters)
    Paulsen) is a genetically modified mouse who shares the same cage as Brain at Acme Labs. Pinky is an extremely unstable and hyperactive mouse. He has several...
    61 KB (7,368 words) - 01:38, 23 April 2024