• Thumbnail for Glucagon-like peptide-1
    Glucagon-like peptide-1 (GLP-1) is a 30- or 31-amino-acid-long peptide hormone deriving from the tissue-specific posttranslational processing of the proglucagon...
    26 KB (3,369 words) - 05:03, 18 March 2024
  • Thumbnail for Glucagon-like peptide-1 receptor
    The glucagon-like peptide-1 receptor (GLP1R) is a G protein-coupled receptor (GPCR) found on beta cells of the pancreas and on neurons of the brain. It...
    34 KB (4,159 words) - 04:59, 15 April 2024
  • Glucagon-like peptide-1 (GLP-1) receptor agonists, also known as GLP-1 analogs, GLP-1DAs or incretin mimetics, are a class of drugs that reduce blood sugar...
    36 KB (3,979 words) - 20:58, 3 May 2024
  • Thumbnail for Glucagon receptor
    The glucagon receptor is a 62 kDa protein that is activated by glucagon and is a member of the class B G-protein coupled family of receptors, coupled to...
    12 KB (1,419 words) - 04:28, 24 September 2023
  • Thumbnail for Semaglutide
    Semaglutide (category GLP-1 receptor agonists)
    under the brand name Wegovy for weight loss. Semaglutide is a glucagon-like peptide-1 receptor agonist. The most common side effects include nausea, vomiting...
    66 KB (5,379 words) - 05:32, 9 May 2024
  • Thumbnail for Glucagon-like peptide-2 receptor
    Glucagon-like peptide-2 receptor (GLP-2R) is a protein that in human is encoded by the GLP2R gene located on chromosome 17. The GLP2 receptor (GLP2R)...
    6 KB (812 words) - 00:33, 10 March 2024
  • glucagon-like peptide receptors (GLPRs) include the following two receptors: Glucagon-like peptide 1 receptor (GLP-1R) – binds glucagon-like peptide 1...
    367 bytes (75 words) - 11:23, 22 February 2024
  • Thumbnail for Glucagon
    Glucagon is a peptide hormone, produced by alpha cells of the pancreas. It raises the concentration of glucose and fatty acids in the bloodstream and...
    24 KB (2,820 words) - 02:59, 22 November 2023
  • Thumbnail for Exenatide
    Exenatide (category GLP-1 receptor agonists)
    breastfeeding is of unclear safety. Exenatide is a glucagon-like peptide-1 receptor agonist (GLP-1 receptor agonist) also known as incretin mimetics. It works...
    24 KB (2,087 words) - 16:42, 11 May 2024
  • glucagon receptor family is a group of closely related G-protein coupled receptors which include: Glucagon receptor Glucagon-like peptide 1 receptor Glucagon-like...
    2 KB (133 words) - 10:09, 17 January 2024
  • Thumbnail for Dulaglutide
    Dulaglutide (category GLP-1 receptor agonists)
    is a glucagon-like peptide-1 receptor agonist (GLP-1 agonist) consisting of GLP-1(7-37) covalently linked to an Fc fragment of human IgG4. GLP-1 is a...
    16 KB (1,512 words) - 06:23, 7 April 2024
  • Thumbnail for Incretin
    Incretin (category Peptide hormones)
    candidate peptides that fulfill criteria for an incretin are the intestinal peptides glucagon-like peptide-1 (GLP-1) and gastric inhibitory peptide (GIP,...
    7 KB (757 words) - 23:21, 3 March 2024
  • liraglutide, which is an agonist for the glucagon-like peptide-1 receptor. It is a chemical analogue of glucagon-like peptide-1 with a fatty acid and spacer attached...
    9 KB (771 words) - 22:13, 26 April 2024
  • Glucagon-like peptide-2 (GLP-2) is a 33 amino acid peptide with the sequence HADGSFSDEMNTILDNLAARDFINWLIQTKITD (see Proteinogenic amino acid) in humans...
    2 KB (258 words) - 20:23, 20 December 2023
  • Thumbnail for Liraglutide
    Liraglutide (category GLP-1 receptor agonists)
    outcomes like heart disease and life expectancy are unclear. It is given by injection under the skin. Liraglutide is a glucagon-like peptide-1 receptor agonist...
    31 KB (2,665 words) - 07:06, 9 May 2024
  • Thumbnail for Orforglipron
    Orforglipron (category GLP-1 receptor agonists)
    non-peptide glucagon-like peptide-1 receptor agonist developed as a weight loss drug by Eli Lilly and Company. It is easier to produce than GLP-1 agonists...
    3 KB (171 words) - 19:31, 8 February 2024
  • 2006). "Design of a long acting peptide functioning as both a glucagon-like peptide-1 receptor agonist and a glucagon receptor antagonist". The Journal of...
    22 KB (2,768 words) - 16:59, 10 April 2024
  • Thumbnail for Peptide hormone
    natriuretic peptide (ANP) Calcitonin Cholecystokinin (CCK) Gastrin Ghrelin Glucagon Glucose-dependent insulinotropic polypeptide (GIP) Glucagon-like peptide-1 (GLP-1)...
    5 KB (547 words) - 21:45, 20 January 2024
  • Thumbnail for Daniel J. Drucker
    Drucker, D. J.; Nauck, M. A. (2006). "The incretin system: Glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes"...
    20 KB (1,905 words) - 01:17, 28 March 2024
  • Thumbnail for Tirzepatide
    Tirzepatide (category GLP-1 receptor agonists)
    constipation, upper abdominal discomfort, and abdominal pain. Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are...
    42 KB (3,387 words) - 15:37, 9 May 2024
  • Thumbnail for Gastric inhibitory polypeptide
    incretin, is to stimulate insulin secretion. GIP, along with glucagon-like peptide-1 (GLP-1), belongs to a class of molecules referred to as incretins,...
    9 KB (1,052 words) - 16:12, 2 May 2024
  • Thumbnail for Formyl peptide receptor 1
    Formyl peptide receptor 1 (FPR1, FPR1 receptor, fMet-Leu-Phe receptor 1, FMLP receptor 1, or N-formylmethionyl-leucyl-phenylalanine receptor 1) is a cell...
    30 KB (3,909 words) - 08:46, 30 April 2024
  • Thumbnail for Danuglipron
    Danuglipron (category GLP-1 receptor agonists)
    (June 2022). "A Small-Molecule Oral Agonist of the Human Glucagon-like Peptide-1 Receptor". Journal of Medicinal Chemistry. 65 (12): 8208–8226. doi:10...
    5 KB (190 words) - 06:47, 8 December 2023
  • Thumbnail for Enteroendocrine cell
    inhibitory peptide, an incretin, which also promotes triglyceride storage. K cells are mostly found in the duodenum. L cells secrete glucagon-like peptide-1, an...
    17 KB (1,686 words) - 13:16, 10 March 2024
  • Thumbnail for Melanocortin 1 receptor
    melanocortin 1 receptor (MC1R), also known as melanocyte-stimulating hormone receptor (MSHR), melanin-activating peptide receptor, or melanotropin receptor, is...
    33 KB (3,769 words) - 04:57, 6 May 2024
  • Thumbnail for Interleukin 6
    weight exerted by glucagon-like peptide-1 (GLP-1) receptor stimulation. Outside the CNS, it seems that IL-6 stimulates the production of GLP-1 in the endocrine...
    64 KB (7,480 words) - 15:44, 8 May 2024
  • High School Glucagon-like peptide-1 (GLP-1) Glucagon-like peptide-1 receptor agonists are sometimes referred to as "GLPs" Glucagon-like peptide-2 (GLP-2)...
    1,001 bytes (142 words) - 07:16, 21 June 2023
  • Enteroglucagon (category Peptide hormones)
    2 diabetes: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors". Diabetes, Obesity & Metabolism. 9 (Suppl 1): 23–31. doi:10...
    6 KB (699 words) - 05:39, 26 March 2024
  • MariTide (category GLP-1 receptor agonists)
    Mathies M.; Christensen, Mikkel B. (3 July 2021). "Emerging glucagon-like peptide 1 receptor agonists for the treatment of obesity". Expert Opinion on Emerging...
    4 KB (187 words) - 21:42, 25 April 2024
  • Thumbnail for Metabolic dysfunction–associated steatotic liver disease
    include glucagon-like peptide-1 receptor agonists (GLP-1 agonists), GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) or glucagon co-agonists...
    129 KB (14,442 words) - 05:01, 6 May 2024