Glucokinase (EC 2.7.1.2) is an enzyme that facilitates phosphorylation of glucose to glucose-6-phosphate. Glucokinase occurs in cells in the liver and... 44 KB (5,668 words) - 04:13, 1 April 2024 |
The glucokinase regulatory protein (GKRP) also known as glucokinase (hexokinase 4) regulator (GCKR) is a protein produced in hepatocytes (liver cells)... 15 KB (1,696 words) - 00:07, 20 December 2023 |
Hexokinase (section Hexokinase IV ("glucokinase")) group from ATP to a substrate. Hexokinases should not be confused with glucokinase, which is a specific hexokinase found in the liver. All hexokinases are... 15 KB (1,561 words) - 05:04, 15 April 2024 |
Enzyme activator (section Glucokinase) cells. Due to this, Glucokinase and glucokinase activators are the focus of treatment for those with type 2 diabetes mellitus. Glucokinase have a single allosteric... 4 KB (574 words) - 00:02, 17 April 2023 |
Glucokinase regulator is a protein that in humans is encoded by the GCKR gene. This gene encodes a protein belonging to the GCKR subfamily of the SIS... 5 KB (632 words) - 19:43, 7 November 2023 |
is converted to F1P in the liver. This negates the action of F6P on glucokinase, which ultimately favors the forward reaction. The capacity of liver... 15 KB (1,642 words) - 02:37, 20 March 2024 |
Glycolysis (section Hexokinase and glucokinase) intracellular starch or glycogen. In animals, an isozyme of hexokinase called glucokinase is also used in the liver, which has a much lower affinity for glucose... 82 KB (8,782 words) - 01:27, 28 April 2024 |
In enzymology, an ADP-specific glucokinase (EC 2.7.1.147) also known as ADP-dependent glucokinase is an enzyme that catalyzes the chemical reaction ADP... 5 KB (628 words) - 13:00, 26 August 2023 |
human chromosome 7 for glucokinase. Glucokinase serves as the glucose sensor for the pancreatic beta cell. Normal glucokinase triggers insulin secretion... 6 KB (684 words) - 13:30, 11 February 2024 |
levels. Glucose is converted into glucose 6-phosphate by the action of glucokinase or hexokinase with conversion of ATP to ADP. Glucose-6-phosphate is converted... 5 KB (608 words) - 04:57, 22 November 2023 |
mutations of transcription factor genes. One form is due to mutations of the glucokinase gene. For each form of MODY, multiple specific mutations involving different... 21 KB (2,261 words) - 20:16, 1 December 2023 |
the association of insulin and SREBP-1 lead to the gene expression of glucokinase. The interaction of glucose and lipogenic gene expression is assumed... 17 KB (2,179 words) - 19:33, 19 February 2023 |
for his contributions in diabetes research, specifically the work of Glucokinase activation as a treatment therapy for type 2 diabetes. Ramakanth Sarabu... 13 KB (1,160 words) - 09:45, 7 April 2024 |
conventional glucokinase and phosphofructokinase, two novel sugar kinase have been discovered. These enzymes are ADP-dependent glucokinase (ADP-GK) and... 15 KB (1,867 words) - 13:14, 9 January 2024 |
Cadisegliatin (TTP399) is a liver-selective glucokinase activator. It is being developed by VTV Therapeutics for treatment of type 2 diabetes or type... 5 KB (432 words) - 20:16, 10 December 2023 |
Catholic novelist and author GK Barry, English influencer and presenter Glucokinase, an enzyme that facilitates phosphorylation of glucose to glucose-6-phosphate... 1 KB (194 words) - 14:25, 10 December 2023 |
fitness, and be favoured by natural selection. An example of an isozyme is glucokinase, a variant of hexokinase which is not inhibited by glucose 6-phosphate... 12 KB (1,461 words) - 10:55, 14 December 2023 |
insulin-producing pancreatic islets and ultimately discovered the essential role of glucokinase (liver and pancreas hexokinase) in the regulation of glucose-stimulated... 8 KB (729 words) - 02:05, 11 March 2024 |
obesity and type 2 diabetes. This includes research identifying the genes glucokinase and HNF1 risk factors for type 2 diabetes. In 2007, he was elected to... 2 KB (173 words) - 18:00, 5 January 2024 |
Globalagliatin (SY-004) is a glucokinase activator developed by Yabao Pharmaceutical Group for type 2 diabetes. Zhao, Yuqing; Xie, Lijun; Zhang, Hongwen;... 4 KB (207 words) - 01:05, 1 January 2024 |
encoding protein GEN1, Holliday junction 5' flap endonuclease GCKR: Glucokinase regulator GFPT1: glutamine—fructose-6-phosphate transaminase 1 GKN1:... 40 KB (2,528 words) - 16:07, 12 March 2024 |
and fat cells. Once within cells, glucose is rapidly phosphorylated by glucokinase in the liver and hexokinase in other tissues to form glucose-6-phosphate... 25 KB (2,937 words) - 17:58, 15 January 2024 |
two sugar monosaccharides, glucose and galactose. Another example is Glucokinase, which is an enzyme involved in the phosphorylation of glucose to glucose-6-phosphate... 16 KB (2,062 words) - 05:15, 30 November 2023 |
reactions are replaced with more kinetically favorable reactions. Hexokinase/glucokinase, phosphofructokinase, and pyruvate kinase enzymes of glycolysis are replaced... 33 KB (3,693 words) - 16:47, 3 April 2024 |