Protease inhibitors that have been developed and are currently used in clinical practice include: Antiretroviral HIV-1 protease inhibitors—class stem...

ligands, like protease inhibitors, that can modulate catalytic activities has an enormous therapeutic effect. Hence, inhibition of the HIV protease is one of...

active protease cannot mature into infectious virions. Several protease inhibitors have been licensed for HIV therapy. There are ten HIV-1 PR inhibitors that...

produced in the presence of protease inhibitors are defective and mostly non-infectious. Examples of HIV protease inhibitors are lopinavir, indinavir, nelfinavir...

medications to treat HIV/AIDS. This combination treatment is known as highly active antiretroviral therapy (HAART). Ritonavir is a protease inhibitor, though it...

inhibitors and cannot function anymore. HIV protease inhibitors are used to treat patients having AIDS virus by preventing its DNA replication. HIV protease...

medication used in the treatment of HIV/AIDS. Nelfinavir belongs to the class of drugs known as protease inhibitors (PIs) and like other PIs is almost...

used in pregnancy and it appears to be safe. Both medications are HIV protease inhibitors. Ritonavir functions by slowing down the breakdown of lopinavir...

Crixivan, made by Merck) is a protease inhibitor used as a component of highly active antiretroviral therapy to treat HIV/AIDS. It is soluble white powder...

Y, Wang Y (2015). "HIV protease inhibitors: a review of molecular selectivity and toxicity". HIV/AIDS. 7: 95–104. doi:10.2147/HIV.S79956. PMC 4396582...

appears to be safe in pregnancy. It is in the protease inhibitor class and works by blocking the HIV protease. Saquinavir was patented in 1988 and first...

on the HIV-1 protease structure. The HIV genome has high plasticity, so has been able to become resistant to multiple HIV-1 protease inhibitors. Since...

antiretroviral of the protease inhibitor class. It is used against HIV infections as a fixed-dose combination with another protease inhibitor, ritonavir (lopinavir/ritonavir)...

treating rheumatic arthritis) and the protease inhibitors used to treat HIV/AIDS. Since anti-pathogen inhibitors generally target only one enzyme, such...

transition state analog inhibitors include flu medications such as the neuraminidase inhibitor oseltamivir and the HIV protease inhibitors saquinavir in the...

therapeutic agents. Other natural protease inhibitors are used as defense mechanisms. Common examples are the trypsin inhibitors found in the seeds of some plants...

produce the HIV peptide coat. Structure–activity studies on renin inhibitors proved to be of great value for developing HIV protease inhibitors. Incorporation...

treat HIV infection.[citation needed] Tipranavir has the ability to inhibit the replication of viruses that are resistant to other protease inhibitors and...

strong UGT1A inhibitors such as ritonavir and other HIV protease inhibitors. (But ritonavir also increases elvitegravir levels by inhibiting CYP3A.) Furthermore...

(HIV protease inhibitor) Darunavir (HIV protease inhibitor) Delavirdine (non-nucleoside reverse transcriptase inhibitor) Fosamprenavir (HIV protease inhibitor)...

Discovery and development of HIV-protease inhibitors HIV/AIDS denialism World AIDS Day Weiss RA (May 1993). "How does HIV cause AIDS?". Science. 260 (5112):...

Lexiva and Telzir, is a medication used to treat HIV/AIDS. It is a prodrug of the protease inhibitor and antiretroviral drug amprenavir. It is marketed...

adverse drug interactions with other drugs which inhibit or induce CYP3A4, including HIV protease inhibitors, ketoconazole, and itraconazole, although coadministration...

Discovery and development of HIV-protease inhibitors Discovery and development of non-nucleoside reverse-transcriptase inhibitors Discovery and development...

transcriptase inhibitors (NRTIs), non-nucleoside reverse transcriptase, inhibitors (NNRTIs), protease inhibitors (PIs), integrase strand transfer inhibitors (INSTIs)...

used to treat HIV-associated lipodystrophy.[citation needed] Reversion of lipodystrophy does not occur after withdrawal of protease inhibitors. Drug-induced...

Brecanavir (INN; codenamed GW640385) is a protease inhibitor which has been studied for the treatment of HIV. In December 2006, its developer, GlaxoSmithKline...

Almarsson O (March 2003). "Elucidation of crystal form diversity of the HIV protease inhibitor ritonavir by high-throughput crystallization". Proc. Natl. Acad...

therapy, deaths from AIDS have stayed low since the introduction of protease inhibitors and combination therapy in the late 1990s. 14% are believed to have...

Reverse-transcriptase inhibitors (RTIs) are a class of antiretroviral drugs used to treat HIV infection or AIDS, and in some cases hepatitis B. RTIs inhibit activity...