• Thumbnail for HLA-G
    HLA-G histocompatibility antigen, class I, G, also known as human leukocyte antigen G (HLA-G), is a protein that in humans is encoded by the HLA-G gene...
    21 KB (2,627 words) - 16:50, 20 January 2024
  • Thumbnail for Human leukocyte antigen
    and three minor MHC class I genes in HLA. Major MHC class I HLA-A HLA-B HLA-C Minor genes are HLA-E, HLA-F and HLA-G. β2-microglobulin binds with major...
    51 KB (5,941 words) - 01:45, 20 March 2024
  • Thumbnail for HLA-B27
    Human leukocyte antigen (HLA) B27 (subtypes B*2701-2759) is a class I surface molecule encoded by the B locus in the major histocompatibility complex...
    16 KB (1,516 words) - 09:54, 16 February 2024
  • Thumbnail for Beta-2 microglobulin
    alloantigen). Nevertheless, the β2 microglobulin gene is outside of the MHC (HLA) locus, on a different chromosome. An additional function is association...
    18 KB (2,117 words) - 03:27, 19 March 2024
  • Thumbnail for HLA-DR4
    HLA-DR4 (DR4) is an HLA-DR serotype that recognizes the DRB1*04 gene products. The DR4 serogroup is large and has a number of moderate frequency alleles...
    26 KB (2,119 words) - 03:34, 29 November 2023
  • Thumbnail for HLA-A
    HLA-A is a group of human leukocyte antigens (HLA) that are encoded by the HLA-A locus, which is located at human chromosome 6p21.3. HLA is a major histocompatibility...
    27 KB (3,411 words) - 01:57, 10 March 2024
  • Thumbnail for MHC class I
    polymorphic HLA-A (HLA-A) HLA-B (HLA-B) HLA-C (HLA-C) Less polymorphic HLA-E (HLA-E) HLA-F (HLA-F) HLA-G (HLA-G) HLA-K (pseudogene) HLA-L (pseudogene)...
    21 KB (2,606 words) - 12:21, 5 April 2024
  • Thumbnail for Untranslated region
    such as cancer. For example, associations between polymorphisms in the HLA-G 3′UTR region and development of colorectal cancer have been discovered....
    12 KB (1,454 words) - 21:01, 18 January 2024
  • Thumbnail for HLA-C
    HLA-C alleles that are Class-I MHC receptors. HLA-C, localized proximal to the HLA-B locus, is located on the distal end of the HLA region. Most HLA-C:B...
    8 KB (1,014 words) - 03:35, 28 December 2023
  • Thumbnail for HLA-DR1
    HLA-DR1 (DR1) is a HLA-DR serotype that recognizes the DRB1*01 gene products. It has been observed to be common among centenarians. The serology for the...
    20 KB (1,596 words) - 01:46, 28 November 2023
  • HLA A1-B8 (Also:HL A1,8; HL A1,A8; HLA A1-Cw7-B8; HLA A*01-B*08, HLA A*0101-B*0801, HLA A*0101-Cw*0701-B*0801; HLA A*01:01-C*07:01-B*08:01) is a multigene...
    23 KB (2,540 words) - 05:37, 25 December 2023
  • Thumbnail for HLA-DR3
    HLA-DR3 is composed of the HLA-DR17 and HLA-DR18 split 'antigens' serotypes. DR3 is a component gene-allele of the AH8.1 haplotype in Northern and Western...
    9 KB (697 words) - 02:42, 27 January 2024
  • Thumbnail for HLA-F
    HLA class I histocompatibility antigen, alpha chain F is a protein that in humans is encoded by the HLA-F gene. It is an empty intracellular molecule...
    36 KB (4,439 words) - 06:11, 25 December 2023
  • Thumbnail for HLA-DR
    HLA-DR is an MHC class II cell surface receptor encoded by the human leukocyte antigen complex on chromosome 6 region 6p21.31. The complex of HLA-DR (Human...
    31 KB (2,293 words) - 12:25, 28 December 2023
  • cells to avoid immune system is upregulation of non-classical MHC I (HLA-E, HLA-F, HLA-G) which prevents NK-mediated immune reaction by interaction with NK...
    11 KB (1,356 words) - 23:48, 15 December 2021
  • Thumbnail for Cancer immunology
    Tumor cells have non-classical MHC class I on their surface, for example HLA-G. HLA-G is inducer of Treg, MDSC, polarise macrophages into alternatively activated...
    33 KB (3,766 words) - 02:41, 25 April 2024
  • Thumbnail for MHC class II
    MHC class II (redirect from Hla-d antigens)
    gene complex (HLA). HLAs corresponding to MHC class II are HLA-DP, HLA-DM, HLA-DOA, HLA-DOB, HLA-DQ, and HLA-DR. Mutations in the HLA gene complex can...
    16 KB (2,022 words) - 06:04, 30 April 2024
  • Thumbnail for HLA-A*02
    of the HLA System revised the nomenclature for HLAs. Before this revision, HLA-A*02 was also referred to as HLA-A2, HLA-A02, and HLA-A*2. HLA-A*02 is...
    31 KB (1,695 words) - 23:27, 8 December 2023
  • Thumbnail for HLA-B51
    HLA-B51 (B51) is an HLA-B serotype. The serotype identifies the more common HLA-B*51 gene products. B51 is a split antigen of the broad antigen B5, and...
    16 KB (960 words) - 17:26, 20 November 2023
  • Thumbnail for HLA-DQ2
    HLA-DQ2 (DQ2) is a serotype group within HLA-DQ (DQ) serotyping system. The serotype is determined by the antibody recognition of β2 subset of DQ β-chains...
    33 KB (3,380 words) - 01:12, 24 February 2024
  • Thumbnail for Tsuneko Okazaki
    the genomic regulation of HLA-G and how the presence of a LINE1 gene silencer may explain the limited expression of HLA-G. She also contributed to the...
    12 KB (1,229 words) - 23:13, 10 February 2024
  • Thumbnail for Natural killer cell
    both classical MHC I (HLA-A, HLA-B, HLA-C) and nonclassical Mamu-G (HLA-G) in primates. Some KIRs are specific for certain HLA subtypes. Most KIRs are...
    74 KB (9,180 words) - 04:00, 11 March 2024
  • contact with the uterine wall - at the placental bed - begin to express the HLA-G antigen. Extravillous trophoblast (EVT) cells migrate from anchoring villi...
    13 KB (1,535 words) - 22:29, 23 March 2023
  • Thumbnail for HLA-DR2
    HLA-DR2 (DR2) of the HLA-DR serotype system, is a broad antigen serotype that is now preferentially covered by HLA-DR15 and HLA-DR16 serotype group. This...
    4 KB (333 words) - 09:16, 3 April 2024
  • Thumbnail for In vitro fertilisation
    PMID 24480786. Rebmann V, Switala M, Eue I, Grosse-Wilde H (July 2010). "Soluble HLA-G is an independent factor for the prediction of pregnancy outcome after ART:...
    175 KB (20,445 words) - 20:01, 6 May 2024
  • Thumbnail for HLA-DRB1
    HLA class II histocompatibility antigen, DRB1 beta chain is a protein that in humans is encoded by the HLA-DRB1 gene. DRB1 encodes the most prevalent beta...
    6 KB (666 words) - 11:10, 3 February 2024
  • Thumbnail for HLA-DQ8
    HLA-DQ8 (DQ8) is a human leukocyte antigen serotype within the HLA-DQ (DQ) serotype group. DQ8 is a split antigen of the DQ3 broad antigen. DQ8 is determined...
    66 KB (5,452 words) - 18:32, 3 December 2023
  • Thumbnail for HLA-E
    HLA class I histocompatibility antigen, alpha chain E (HLA-E) also known as MHC class I antigen E is a protein that in humans is encoded by the HLA-E...
    7 KB (954 words) - 16:08, 1 April 2024
  • Thumbnail for HLA-B35
    HLA-B35 (B35) is an HLA-B serotype. The serotype identifies the more common HLA-B*35 gene products. B35 is one of the largest B serotype groups, it currently...
    6 KB (149 words) - 12:06, 21 July 2019
  • Thumbnail for KIR2DL4
    The only so far reported ligand of KIR2DL4 is the non-classical HLA class 1 gene HLA-G, leading to the inhibition of the cytolytic NK cell function. Cluster...
    9 KB (1,225 words) - 00:37, 8 November 2023