• Thumbnail for Hemoglobinuria
    Hemoglobinuria is a condition in which the oxygen transport protein hemoglobin is found in abnormally high concentrations in the urine. The condition is...
    3 KB (180 words) - 08:40, 23 January 2024
  • Thumbnail for Paroxysmal nocturnal hemoglobinuria
    Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired, life-threatening disease of the blood characterized by destruction of red blood cells by...
    26 KB (3,025 words) - 22:23, 19 March 2024
  • Paroxysmal hemoglobinuria can refer to: Paroxysmal nocturnal hemoglobinuria Paroxysmal cold hemoglobinuria Hemoglobinuria This disambiguation page lists...
    176 bytes (44 words) - 17:17, 29 December 2019
  • inhibitor medication designed for the treatment of paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome. It is designed to bind...
    10 KB (724 words) - 07:04, 1 April 2024
  • Exertional hemoglobinuria (or exercise hematuria) may refer to: March hemoglobinuria caused by impacts upon the body Hemoglobinuria secondary to athletic...
    193 bytes (53 words) - 11:20, 28 December 2019
  • Paroxysmal cold hemoglobinuria (PCH) or Donath–Landsteiner hemolytic anemia (DLHA) is an autoimmune hemolytic anemia featured by complement-mediated intravascular...
    36 KB (3,858 words) - 14:51, 29 February 2024
  • may result in hemoglobinuria. The damage is induced through repetitive mechanical motions such as prolonged marching (march hemoglobinuria) and marathon...
    4 KB (509 words) - 10:32, 14 August 2023
  • recombinant humanized monoclonal antibody used to treat paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), generalized myasthenia...
    41 KB (3,628 words) - 04:54, 24 February 2024
  • investigation by Roche/Genentech for the treatment of paroxysmal nocturnal hemoglobinuria (PNH). Following an initial i.v. loading dose, crovalimab is administered...
    9 KB (681 words) - 01:17, 18 April 2024
  • Empaveli, among others, is a medication used to treat paroxysmal nocturnal hemoglobinuria and geographic atrophy of the retina. Pegcetacoplan is a complement...
    19 KB (1,538 words) - 05:19, 3 March 2024
  • Thumbnail for Iptacopan
    Fabhalta, is a medication used for the treatment of paroxysmal nocturnal hemoglobinuria. It is a complement factor B inhibitor that was developed by Novartis...
    11 KB (711 words) - 22:30, 23 March 2024
  • Thumbnail for Danicopan
    Voydeya, is a medication used for the treatment of paroxysmal nocturnal hemoglobinuria. It is a complement inhibitor which reversibly binds to factor D to...
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  • presentation must be excluded, such as aplastic anemia, paroxysmal nocturnal hemoglobinuria, myelodysplasia and leukemias. This requires a bone marrow examination...
    11 KB (1,105 words) - 08:22, 10 March 2024
  • Thumbnail for Hemolytic anemia
    a result of certain infections (e.g. malaria). Paroxysmal nocturnal hemoglobinuria (PNH), sometimes referred to as Marchiafava-Micheli syndrome, is a rare...
    30 KB (3,326 words) - 18:56, 17 December 2023
  • Thumbnail for Sucrose lysis test
    diagnostic laboratory test used for diagnosing paroxysmal nocturnal hemoglobinuria (PNH), as well as for hypoplastic anemias and any hemolytic anemia with...
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  • Thumbnail for Urine test strip
    hemoglobin (hemoglobinuria). Blood present in large quantities can be detected visually. Hematuria produces cloudy red urine, and hemoglobinuria appears as...
    54 KB (6,376 words) - 02:56, 10 March 2024
  • which are the culprits of cold agglutinin disease, paroxysmal cold hemoglobinuria in the process of Donath–Landsteiner hemolytic anemia, and vasculitis...
    18 KB (1,683 words) - 07:22, 3 December 2023
  • Thumbnail for PIGA
    serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from somatic...
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  • malaria, tabes dorsalis, and Behçet's disease, paroxysmal nocturnal hemoglobinuria (PNH). It has also been noted as a symptom of gratification disorder...
    3 KB (288 words) - 20:40, 15 January 2024
  • test is a blood test used in the diagnosis of paroxysmal nocturnal hemoglobinuria (PNH). Patient red blood cells (RBCs) are placed in mild acid; a positive...
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  • Thumbnail for Budd–Chiari syndrome
    syndrome include antiphospholipid syndrome and paroxysmal nocturnal hemoglobinuria, which are responsible for 10–12% and 7–12% of Budd–Chiari syndrome...
    19 KB (2,142 words) - 02:37, 6 September 2023
  • is used in a flow cytometric assay to diagnose paroxysmal nocturnal hemoglobinuria (PNH). The assay takes advantage of the action of proaerolysin, a prototoxin...
    1 KB (152 words) - 18:42, 27 July 2020
  • Thumbnail for Babesiosis
    due to the failure of the liver to metabolize the excess bilirubin. Hemoglobinuria is seen due to excretion of red-blood-cell lysis byproducts via the...
    33 KB (3,233 words) - 23:10, 22 April 2024
  • Thumbnail for Decay-accelerating factor
    mutations that reduce GPI levels such as those with paroxysmal nocturnal hemoglobinuria (PNH). In PNH disorder, red blood cells with very low levels of DAF...
    8 KB (962 words) - 14:13, 29 January 2023
  • autoimmune hemolytic anemia Cold agglutinin disease Paroxysmal cold hemoglobinuria (rare) Infectious mononucleosis Alloimmune hemolytic anemia Hemolytic...
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  • Thumbnail for Anemia
    cause premature destruction. All of these, except paroxysmal nocturnal hemoglobinuria, are hereditary genetic disorders. Hereditary spherocytosis is a hereditary...
    84 KB (8,637 words) - 11:08, 13 April 2024
  • synthesis occur in rare acquired diseases such as paroxysmal nocturnal hemoglobinuria (PNH) and congenital diseases such as hyperphosphatasia with mental...
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  • atypical hemolytic uremic syndrome (aHUS) and paroxysmal nocturnal hemoglobinuria (PNH); asfotase alfa (Strensiq), used to treat hypophosphatasia; sebelipase...
    20 KB (1,377 words) - 17:48, 12 March 2024
  • Antibody test: immune competency Blood tests for paroxysmal nocturnal hemoglobinuria Bone marrow aspirate and biopsy: to rule out other causes of pancytopenia...
    40 KB (4,363 words) - 21:36, 12 March 2024
  • Thumbnail for Red cell agglutination
    cause). Red cell agglutination can also occur in paroxysmal nocturnal hemoglobinuria: 13  and warm autoimmune hemolytic anemia.: 88  In cases of red cell...
    4 KB (407 words) - 03:17, 5 November 2023