• Thumbnail for Hepatotoxicity
    Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage. Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease...
    39 KB (4,060 words) - 02:49, 19 April 2024
  • Thumbnail for Paracetamol poisoning
    inducer isoniazid increases the risk of hepatotoxicity, though whether 2E1 induction is related to the hepatotoxicity in this case is unclear. Concomitant...
    64 KB (7,245 words) - 03:16, 21 March 2024
  • Thumbnail for Kava
    addition to the kava lactones is important to provide protection against hepatotoxicity". It has also been argued that kavalactone extracts have often been...
    71 KB (7,995 words) - 09:07, 17 April 2024
  • published in the World Journal of Hepatology reexamined known cases of hepatotoxicity that had previously been linked to consumption of Herbalife products...
    69 KB (6,524 words) - 13:12, 30 April 2024
  • Thumbnail for Cholestasis
    Cholestasis is a condition where the flow of bile from the liver to the duodenum is impaired. The two basic distinctions are: obstructive type of cholestasis...
    112 KB (12,671 words) - 02:27, 18 March 2024
  • Thumbnail for Hydrazine (antidepressant)
    the 1950s and 1960s. Most have been withdrawn due to toxicity, namely hepatotoxicity, but a few still remain in clinical use. Tranylcypromine, a structurally...
    2 KB (155 words) - 22:46, 12 May 2023
  • Thumbnail for Rosiglitazone
    Rosiglitazone (trade name Avandia) is an antidiabetic drug in the thiazolidinedione class. It works as an insulin sensitizer, by binding to the PPAR in...
    56 KB (5,929 words) - 06:17, 17 April 2024
  • Thumbnail for Toxicity
    organism, such as a cell (cytotoxicity) or an organ such as the liver (hepatotoxicity). Sometimes the word is more or less synonymous with poisoning in everyday...
    27 KB (3,097 words) - 18:23, 23 March 2024
  • Thumbnail for Troglitazone
    $136 million. Since the withdrawal in 2000, mechanisms of troglitazone hepatotoxicity have been extensively studied using a variety of in vivo, in vitro,...
    20 KB (2,044 words) - 20:03, 20 December 2023
  • Thumbnail for Niacin
    fatal or non-fatal strokes. Prescription niacin was shown to cause hepatotoxicity and increase risk of type 2 diabetes. Niacin prescriptions in the U...
    91 KB (8,699 words) - 18:17, 10 April 2024
  • Auclert, L; Le-Louët, H (November 2021). "Safety data and withdrawal of hepatotoxic drugs". Therapie. 76 (6): 715–723. doi:10.1016/j.therap.2018.02.004....
    46 KB (1,956 words) - 13:53, 13 April 2024
  • Thumbnail for Erythromycin
    stenosis. Erythromycin estolate has been associated with reversible hepatotoxicity in pregnant women in the form of elevated serum glutamic-oxaloacetic...
    41 KB (3,748 words) - 08:27, 27 April 2024
  • Thumbnail for Drostanolone propionate
    fluid retention. Drostanolone propionate is not known to pose a risk of hepatotoxicity. Drostanolone propionate is a prodrug of drostanolone. Like other AAS...
    16 KB (1,277 words) - 16:55, 21 December 2023
  • Thumbnail for Scleroderma
    (US) Malignancies, injection site reactions, blood clots, lymphopenia, hepatotoxicity and infections. Azathioprine Purine analogue that inhibits lymphocyte...
    38 KB (3,291 words) - 06:52, 29 April 2024
  • for hepatotoxicity during drug metabolism with a number of different drugs, including flucloxacilin, trioleandomycin, and troglitazone. Hepatotoxicity indicates...
    8 KB (928 words) - 21:12, 5 December 2023
  • Thumbnail for Kombucha
    ISBN 978-0-1241-5783-5. Abdualmjid, Reem J; Sergi, Consolato (2013). "Hepatotoxic Botanicals—An Evidence-based Systematic Review". Journal of Pharmacy...
    36 KB (3,652 words) - 19:52, 22 April 2024
  • liver damage can be attributed to a particular medication. Determining hepatotoxicity (toxic effects of a substance on the liver) remains a major challenge...
    3 KB (276 words) - 15:54, 15 April 2024
  • Thumbnail for Rumack–Matthew nomogram
    half-life is more than 4 hours, then treatment is necessary to prevent hepatotoxicity and liver failure. The original line, sometimes referred to as the Rumack–Matthew...
    5 KB (488 words) - 17:54, 7 July 2023
  • Thumbnail for Valerian (herb)
    of this uncertainty and the potential for toxicity in the fetus and hepatotoxicity in the mother, valerian use is discouraged during pregnancy. Headache...
    20 KB (2,024 words) - 16:30, 16 April 2024
  • Thumbnail for Ketoconazole
    analogue, male-limited precocious puberty. In any case, the risk of hepatotoxicity with ketoconazole limits its use in all of these indications, especially...
    50 KB (4,374 words) - 18:23, 30 April 2024
  • Thumbnail for Electronic waste
    degradation. Studies in mice have found the following health effects: Hepatotoxicity, developmental toxicity, immunotoxicity, hormonal effects and carcinogenic...
    152 KB (15,937 words) - 20:57, 29 April 2024
  • Thumbnail for Green tea
    Excessive consumption of green tea extract has been associated with hepatotoxicity and liver failure. In 2018, a scientific panel for the European Food...
    59 KB (6,714 words) - 08:35, 13 April 2024
  • Thumbnail for Ginseng
    potential interaction has been reported with imatinib, resulting in hepatotoxicity, and with lamotrigine. The common ginsengs (P. ginseng and P. quinquefolia)...
    32 KB (3,104 words) - 16:55, 25 April 2024
  • Nicotine gum is a chewing gum containing the active ingredient nicotine polacrilex. It is a type of nicotine replacement therapy (NRT) used alone or in...
    17 KB (1,871 words) - 06:21, 27 November 2023
  • Thumbnail for Zafirlukast
    but serious side effects like acute liver injury. Zafirlukast-induced hepatotoxicity generally occurs within the first 2–6 months of initiating therapy,...
    26 KB (2,524 words) - 16:38, 3 April 2024
  • Thumbnail for Antifungal
    Kyriakidis I, Tragiannidis A, Munchen S, Groll AH (February 2017). "Clinical hepatotoxicity associated with antifungal agents". Expert Opinion on Drug Safety. 16...
    28 KB (2,564 words) - 04:52, 24 February 2024
  • Thumbnail for Oxandrolone
    many[who?] valued oxandrolone's supposed[clarification needed] low hepatotoxicity relative to most other orally active AASs. Like other AASs, oxandrolone...
    47 KB (4,508 words) - 12:16, 22 April 2024
  • Thumbnail for Noni juice
    hepatotoxicity; however, an increasing number of subsequent case reports suggested that some individuals may be particularly sensitive to hepatotoxic...
    10 KB (1,054 words) - 04:05, 28 November 2023
  • chemical substance to prevent damage to the liver. This is opposite to hepatotoxicity. Acetylcysteine is considered the hepatoprotective drug of choice when...
    2 KB (224 words) - 19:21, 9 March 2022
  • Dostarlimab, sold under the brand name Jemperli, is a monoclonal antibody used as an anti-cancer medication for the treatment of endometrial cancer. Dostarlimab...
    36 KB (3,089 words) - 05:24, 26 March 2024