• Thumbnail for Immunohistochemistry
    Immunohistochemistry (IHC) is a form of immunostaining. It involves the process of selectively identifying antigens (proteins) in cells and tissue, by...
    30 KB (3,341 words) - 23:54, 4 April 2024
  • Thumbnail for AE1/AE3
    AE1/AE3 is an antibody cocktail that is used in immunohistochemistry, being generally positive in the cytoplasm of carcinomas (cancers of epithelial origin)...
    3 KB (208 words) - 22:24, 11 December 2023
  • Thumbnail for Histology
    embedding media, but acrylic resins are also used, particularly where immunohistochemistry is required. For tissues to be cut in a frozen state, tissues are...
    33 KB (3,169 words) - 21:39, 6 March 2024
  • Thumbnail for Fixation (histology)
    processing steps and final analyses that are planned. For example, immunohistochemistry uses antibodies that bind to a specific protein target. Prolonged...
    19 KB (2,387 words) - 06:19, 26 November 2023
  • Thumbnail for Immunocytochemistry
    compartments are expressing the antigen. Immunocytochemistry differs from immunohistochemistry in that the former is performed on samples of intact cells that have...
    7 KB (924 words) - 16:17, 24 October 2023
  • Thumbnail for HER2
    needle biopsy, vacuum-assisted breast biopsy, or surgical excision. Immunohistochemistry (IHC) is generally used to measure the amount of HER2 protein present...
    42 KB (4,641 words) - 08:52, 1 May 2024
  • Thumbnail for CD5 (protein)
    CD5 is a cluster of differentiation expressed on the surface of T cells (various species) and in a subset of murine B cells known as B-1a. The expression...
    11 KB (1,469 words) - 15:15, 9 April 2024
  • Thumbnail for Immunostaining
    and molecular biology that use antibody-based staining methods. Immunohistochemistry or IHC staining of tissue sections (or immunocytochemistry, which...
    11 KB (1,287 words) - 15:26, 26 September 2023
  • Thumbnail for Tissue microarray
    independent tests. Tests commonly employed in tissue microarray include immunohistochemistry, and fluorescent in situ hybridization. Tissue microarrays are particularly...
    7 KB (758 words) - 02:56, 1 December 2023
  • Thumbnail for Protein
    Methods commonly used to study protein structure and function include immunohistochemistry, site-directed mutagenesis, X-ray crystallography, nuclear magnetic...
    87 KB (9,875 words) - 00:02, 21 April 2024
  • Thumbnail for Bovine serum albumin
    and immunohistochemistry. Because BSA is a small, stable, moderately non-reactive protein, it is often used as a blocker in immunohistochemistry. During...
    15 KB (1,490 words) - 21:37, 21 April 2024
  • Thumbnail for Invasive cribriform carcinoma of the breast
    The diagnosis of ICCB tumors is based on the histopathology and immunohistochemistry of their hematoxylin and eosin-stained tissues, particularly on identifying...
    23 KB (2,794 words) - 00:41, 3 December 2023
  • Thumbnail for Complement receptor 2
    dendritic cells (FDCs), this becomes readily apparent only when immunohistochemistry is performed on frozen sections. In more conventional paraffin-embedded...
    14 KB (1,830 words) - 18:43, 3 May 2024
  • Thumbnail for Hyperplastic polyp
    where nuclei are enlarged, the nucleus/cytoplasm ratio is elevated. Immunohistochemistry using Ki-67 stains the basal 1⁄3 to 1⁄2 of crypts, indicating a proliferative...
    8 KB (706 words) - 19:06, 22 February 2024
  • Thumbnail for BerEp4
    Angela Felicia; Tan, Sukmawati Tansil (2017). "The Use of BEREP4 Immunohistochemistry Staining for Detection of Basal Cell Carcinoma". Journal of Skin...
    3 KB (210 words) - 23:22, 15 December 2021
  • Mammary secretory carcinoma (MSC), also termed secretory carcinoma of the breast, is a rare form of the breast cancers. MSC usually affects women but in...
    26 KB (3,130 words) - 18:36, 3 December 2023
  • The immunohistochemistry (IHC) test is a laboratory method that detects antibodies of prions (mis-shapen proteins thought to transmit bovine spongiform...
    2 KB (216 words) - 18:23, 4 May 2024
  • Thumbnail for CD31
    cells, B cells, and NK cells), megakaryocytes, and osteoclasts. In immunohistochemistry, CD31 is used primarily to demonstrate the presence of endothelial...
    26 KB (3,115 words) - 18:11, 29 January 2024
  • Thumbnail for Pathology
    needs to be performed on biopsies, including immunofluorescence, immunohistochemistry, electron microscopy, flow cytometry, and molecular-pathologic analysis...
    51 KB (5,547 words) - 20:04, 19 April 2024
  • Thumbnail for Lung cancer
    "Histology and Prognosis". Rudin et al. 2021, "Immunohistochemistry". Horn & Iams 2022, "Immunohistochemistry". Lim et al. 2018, "Table 5: Overall stage based...
    89 KB (9,708 words) - 17:02, 19 April 2024
  • cytogenetics, fluorescence in situ hybridization (FISH), flow cytometry, immunohistochemistry, anatomic pathology, and molecular genetics. Headquartered in Fort...
    5 KB (341 words) - 19:56, 13 April 2024
  • Thumbnail for Typhus
    antibodies associated with typhus. It can also be done with either immunohistochemistry (IHC) or polymerase chain reaction (PCR) tests excluding scrub typhus...
    34 KB (3,413 words) - 16:30, 27 April 2024
  • Thumbnail for Amyloidosis
    in the tissue (immunohistochemistry); or extraction of the protein and identification of its individual amino acids. Immunohistochemistry can identify AA...
    55 KB (5,432 words) - 21:07, 18 April 2024
  • Thumbnail for Inflammatory linear verrucous epidermal nevus
    Inflammatory Linear Verrucous Epidermal Nevus is a rare disease of the skin that presents as multiple, discrete, red papules that tend to coalesce into...
    9 KB (1,020 words) - 19:57, 3 December 2023
  • Thumbnail for Neoplasm
    (2011). "Head and neck squamous cell carcinoma: mismatch repair immunohistochemistry and promoter hypermethylation of hMLH1 gene". Am J Otolaryngol. 32...
    51 KB (5,873 words) - 19:44, 3 May 2024
  • Thumbnail for Pseudomyxoma peritonei
    Pseudomyxoma peritonei (PMP) is a clinical condition caused by cancerous cells (mucinous adenocarcinoma) that produce abundant mucin or gelatinous ascites...
    20 KB (2,341 words) - 21:45, 12 December 2023
  • Thumbnail for CD3 (immunology)
    CD3 (cluster of differentiation 3) is a protein complex and T cell co-receptor that is involved in activating both the cytotoxic T cell (CD8+ naive T cells)...
    7 KB (757 words) - 08:44, 5 May 2024
  • Thumbnail for Atypical teratoid rhabdoid tumor
    molecular markers are characteristic of particular cancer types. Immunohistochemistry is also widely used in basic research to understand the distribution...
    54 KB (6,317 words) - 09:40, 11 December 2023
  • Thumbnail for BRCA2
    cancer Under-expression 42% immunohistochemistry (recurrent cancer in study above) Increased-expression 71% immunohistochemistry Non-small cell lung cancer...
    72 KB (7,828 words) - 14:11, 16 April 2024
  • Thumbnail for Kidney cancer
    Typical immunohistochemistry for various kidney cancer types. PAX8 CD10 CAIX RCC Melanocytic markers Vimentin CK7 HMWCK CD117 / KIT AMACR GATA3 Clear cell...
    49 KB (4,786 words) - 21:50, 13 January 2024