immunoglobulin-like receptor 2DL4 is a protein that in humans is encoded by the KIR2DL4 gene. Killer cell immunoglobulin-like receptors (KIRs) are transmembrane...
9 KB (1,225 words) - 00:37, 8 November 2023
IL1RAPL2 IL1RL1 IL1RL2 IL6R JAM2 JAM3 KIR-123FM KIR2DL1 KIR2DL2 KIR2DL3 KIR2DL4 KIR2DL5A KIR2DL5B KIR2DLX KIR2DS1 KIR2DS2 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DL1...
6 KB (493 words) - 11:53, 22 March 2024
expressed on NK cells. CD158a is KIR2DL1, CD158b is KIR2DL3, CD158d is KIR2DL4. Innate and Bristol Myers are testing monoclonal antibody Lirilumab, which...
96 KB (467 words) - 06:58, 14 October 2022
O60870 8198 KIR2DL1 HGNC:6329 P43626 8199 KIR2DL3 HGNC:6331 P43628 8200 KIR2DL4 HGNC:6332 Q99706 8201 KIR2DS4 HGNC:6336 P43632 8202 KIR3DL1 HGNC:6338 P43629...
277 KB (17 words) - 15:46, 9 May 2024
cells. HLA-G is a ligand for natural killer (NK) cell inhibitory receptor KIR2DL4, and therefore expression of this HLA by the trophoblast defends it against...
21 KB (2,627 words) - 16:50, 20 January 2024
nucleotide sequence fundamentally alter KIR function. With the exception of KIR2DL4, which has both activating and inhibitory capabilities, KIR receptors with...
31 KB (3,830 words) - 05:44, 5 December 2023
receptor NKG2A) and HLA-G (which is a ligand for NK cell inhibitory receptor KIR2DL4) by the trophoblast is thought to defend it against NK cell-mediated death...
74 KB (9,180 words) - 04:00, 11 March 2024
protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked...
8 KB (993 words) - 11:15, 14 August 2023
several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR2DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular...
9 KB (1,105 words) - 23:05, 3 February 2024
receptors (KIRs) Two domains, long cytoplasmic tail KIR2DL1 KIR2DL2 KIR2DL3 KIR2DL4 KIR2DL5A KIR2DL5B Two domains, short cytoplasmic tail KIR2DS1 KIR2DS2 KIR2DS3...
38 KB (2,656 words) - 12:11, 30 October 2023
Carosella ED (April 2005). "HLA-G up-regulates ILT2, ILT3, ILT4, and KIR2DL4 in antigen presenting cells, NK cells, and T cells". FASEB Journal. 19...
12 KB (1,447 words) - 15:32, 5 April 2024
several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR2DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular...
11 KB (1,372 words) - 06:23, 1 January 2024