• Thumbnail for L1 (protein)
    L1, also known as L1CAM, is a transmembrane protein member of the L1 protein family, encoded by the L1CAM gene. This protein, of 200-220 kDa, is a neuronal...
    33 KB (4,002 words) - 05:17, 10 March 2024
  • Thumbnail for PD-L1
    Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by...
    23 KB (2,846 words) - 19:10, 5 May 2024
  • sequences L1 family, a protein family of cell adhesion molecules L1 (protein), a cell adhesion molecule L1 or LINE1; transposable elements in the DNA L1, Lagrangian...
    4 KB (662 words) - 17:05, 14 April 2024
  • Thumbnail for PD-1 and PD-L1 inhibitors
    and PD-L1 inhibitors are a group of checkpoint inhibitor anticancer drugs that block the activity of PD-1 and PDL1 immune checkpoint proteins present...
    31 KB (3,266 words) - 05:22, 6 May 2024
  • Thumbnail for Programmed cell death protein 1
    immune responses. PD-1 has two ligands, PD-L1 and PD-L2, which are members of the B7 family. PD-L1 protein is upregulated on macrophages and dendritic...
    39 KB (5,010 words) - 04:36, 6 May 2024
  • Thumbnail for Ubiquitin carboxy-terminal hydrolase L1
    (accounts for 1-2% of total brain protein), expressed specifically in neurons and testis/ovary. The catalytic triad of UCH-L1 contains a cysteine at position...
    21 KB (2,637 words) - 03:01, 26 November 2023
  • Thumbnail for Papillomaviridae
    host cell, and a late region (L) encoding a major capsid protein L1 and a minor capsid protein L2. All viral ORFs are encoded on one DNA strand (see figure)...
    63 KB (7,242 words) - 05:09, 15 April 2024
  • Thumbnail for Shope papilloma virus
    genome, 360 L1 protein copies, and 12 copies of L2 proteins inside. L2 proteins gather at PML body nuclear structures and recruit L1 proteins during virus...
    16 KB (1,948 words) - 03:45, 14 May 2024
  • Thumbnail for Mitochondrial ribosomal protein L1
    39S ribosomal protein L1, mitochondrial is a protein that in humans is encoded by the MRPL1 gene. Mammalian mitochondrial ribosomal proteins are encoded...
    5 KB (572 words) - 22:35, 3 March 2023
  • Thumbnail for Apolipoprotein L1
    Apolipoprotein L1 is a protein that in humans is encoded by the APOL1 gene. Two transcript variants encoding two different isoforms have been found for...
    24 KB (3,155 words) - 11:15, 25 January 2024
  • Thumbnail for LINE1
    LINE1 (category Protein pages needing a picture)
    unknown function. The first ORF of L1 encodes a 500-amino acid, 40-kDa protein that lacks homology with any protein of known function. In vertebrates,...
    25 KB (2,724 words) - 06:45, 14 May 2024
  • Thumbnail for L1 syndrome
    cell adhesion molecule (sometimes called the L1 protein). The L1 cell adhesion molecule is a surface protein found on the surface of all neurons. It allows...
    33 KB (3,549 words) - 03:26, 19 February 2024
  • The L1 family is a family of cell adhesion molecules that includes four different L1-like proteins. They are members of the immunoglobulin superfamily...
    4 KB (500 words) - 17:23, 12 May 2024
  • Cervarix (category Protein subunit vaccines)
    vaccine are: Human papillomavirus type 16 L1 protein 20 micrograms Human papillomavirus type 18 L1 protein 20 micrograms AS04 adjuvant, containing: 3-O-desacyl-4'-...
    20 KB (1,789 words) - 18:59, 6 January 2024
  • Thumbnail for Cancer immunotherapy
    transmembrane programmed cell death 1 protein (PDCD1, PD-1; also known as CD279) and its ligand, PD-1 ligand 1 (PD-L1, CD274). PD-L1 on the cell surface binds to...
    90 KB (9,943 words) - 09:46, 14 May 2024
  • Thumbnail for HPV vaccine
    HPV vaccine (category Protein subunit vaccines)
    Retrieved 3 April 2020. "Gardasil HPV 6 L1 Protein / HPV 11 L1 Protein / HPV 16 L1 Protein / HPV 18 L1 Protein 20,40,40,20 micrograms/0.5mL sterile liquid...
    180 KB (17,202 words) - 15:28, 13 May 2024
  • Thumbnail for Late protein
    (HPV), two late proteins are involved in capsid formation: a major (L1) and a minor (L2) protein, in the approximate proportion 95:5%. L1 forms a pentameric...
    5 KB (490 words) - 00:54, 29 November 2023
  • Thumbnail for Chaperone (protein)
    molecular chaperones are proteins that assist the conformational folding or unfolding of large proteins or macromolecular protein complexes. There are a...
    29 KB (3,499 words) - 07:16, 20 February 2024
  • Thumbnail for 3T3-L1
    3T3-L1 is a sub clonal cell line derived from the original 3T3 Swiss albino cell line of 1962. The 3T3 original cell line was isolated from a mouse embryo...
    17 KB (1,907 words) - 21:39, 15 April 2024
  • Thumbnail for Bovine papillomavirus
    around 50–60 nm in diameter. The capsid is formed of the L1 and L2 structural proteins, with the L1 C-terminus exposed. All BPVs have a circular double-stranded...
    17 KB (1,882 words) - 06:24, 12 September 2023
  • programmed death cell ligand 1 (PD-L1) protein or BRCA gene mutation. Also known as immunotherapy the presence of PD-L1 on cancer cells mates with an associate...
    28 KB (3,411 words) - 04:07, 14 March 2024
  • Thumbnail for Retrotransposon
    transcriptase and protein rich in amino acids cysteines and histidines. The end of the human LINE1, as with other retrotransposons is adenine-rich. Human L1 actively...
    24 KB (3,103 words) - 21:53, 3 May 2024
  • Thumbnail for Cathepsin L1
    Cathepsin L1 is a protein that in humans is encoded by the CTSL1 gene. The protein is a cysteine cathepsin, a lysosomal cysteine protease that plays a...
    14 KB (1,692 words) - 07:49, 8 March 2024
  • Thumbnail for Atezolizumab
    engineered monoclonal antibody of IgG1 isotype against the protein programmed cell death-ligand 1 (PD-L1). The most common side effects when used on its own...
    43 KB (4,160 words) - 04:59, 13 April 2024
  • Thumbnail for Macular degeneration
    atrophic macular degeneration. This is because Alu elements undergo L1 (protein)-mediated reverse transcription in the cytoplasm resulting in DNA synthesis...
    90 KB (9,795 words) - 00:00, 12 May 2024
  • attachment to ribosomes that capture nascent L1 proteins. Thus, an Alu element can take control of the L1 protein's reverse transcriptase, ensuring that the...
    27 KB (3,083 words) - 20:29, 23 April 2024
  • Virus-like particle (category Viral structural proteins)
    the L1 proteins of HPV types 6, 11, 16, and 18 expressed in yeast. It is adjuvanted with aluminum hydroxyphosphate sulfate. Gardasil-9 consists of L1 epitopes...
    22 KB (2,535 words) - 21:43, 4 May 2024
  • Protein targeting or protein sorting is the biological mechanism by which proteins are transported to their appropriate destinations within or outside...
    52 KB (6,394 words) - 03:48, 19 March 2024
  • Thumbnail for Undifferentiated pleomorphic sarcoma
    expressed IDO1 protein (i.e. indoleamine 2,3-dioxygenase protein). Tumor cells that strongly expressed PD-L1 also expressed CMTM6 protein (i.e. CKLF like...
    41 KB (4,768 words) - 04:20, 4 January 2024
  • Thumbnail for Long interspersed nuclear element
    the phylogeny of the essential protein ORF2p, LINEs can be separated into six main groups, referred to as R2, RanI, L1, RTE, I and Jockey. These groups...
    29 KB (2,765 words) - 17:38, 31 December 2023