• Thumbnail for Solid lipid nanoparticle
    Lipid nanoparticles (LNPs) are nanoparticles composed of lipids. They are a novel pharmaceutical drug delivery system (and part of nanoparticle drug delivery)...
    23 KB (2,629 words) - 15:37, 19 March 2024
  • Thumbnail for MRNA vaccine
    mRNA is delivered by a co-formulation of the RNA encapsulated in lipid nanoparticles that protect the RNA strands and help their absorption into the cells...
    78 KB (7,926 words) - 15:19, 26 April 2024
  • delivery of mRNA is achieved by a coformulation of the molecule into lipid nanoparticles, which protect the RNA strands and help their absorption into the...
    192 KB (21,930 words) - 19:29, 15 April 2024
  • Thumbnail for Nanoparticle
    A nanoparticle or ultrafine particle is a particle of matter 1 to 100 nanometres (nm) in diameter. The term is sometimes used for larger particles, up...
    125 KB (12,961 words) - 17:38, 22 April 2024
  • Thumbnail for Lipid
    disease." Solid lipid nanoparticle – Novel drug delivery system Simple lipid Emulsion test Lipid microdomain Membrane lipid – Lipid molecules on cell...
    70 KB (7,365 words) - 17:15, 1 April 2024
  • Thumbnail for Liposome
    Liposome (redirect from Lipid shell)
    for administration of pharmaceutical drugs and nutrients, such as lipid nanoparticles in mRNA vaccines, and DNA vaccines. Liposomes can be prepared by...
    38 KB (4,095 words) - 16:39, 24 April 2024
  • expressed in brain endothelial cells. Also, solid lipid nanoparticles (SLNs) are lipid nanoparticles with a solid interior as shown in the diagram on the...
    33 KB (4,222 words) - 07:35, 15 November 2023
  • Thumbnail for RNA interference
    help facilitate siRNA delivery to target cells: lipid nanoparticles and conjugates. Lipid nanoparticles (LNPs) are based on liposome-like structures that...
    141 KB (15,437 words) - 06:13, 22 April 2024
  • Thumbnail for Katalin Karikó
    mRNA in lipid nanoparticles, a novel pharmaceutical drug delivery system for mRNA. The mRNA is injected into tiny fat droplets (lipid nanoparticles) which...
    38 KB (4,177 words) - 12:44, 18 April 2024
  • SM-102 (category Lipids)
    SM-102 is a synthetic amino lipid which is used in combination with other lipids to form lipid nanoparticles. These are used for the delivery of mRNA-based...
    7 KB (628 words) - 18:17, 27 March 2024
  • Thumbnail for Acuitas Therapeutics
    development of delivery systems for nucleic acid therapeutics based on lipid nanoparticle (LNP) technology, a key component of the mRNA vaccines deployed for...
    25 KB (2,038 words) - 17:47, 19 February 2024
  • Thumbnail for ALC-0315
    ALC-0315 (category Lipids)
    and Pfizer. Specifically, it is one of four components that form lipid nanoparticles (LNPs), which encapsulate and protect the otherwise fragile mRNA...
    8 KB (782 words) - 12:58, 24 January 2024
  • diseases and infectious diseases. Arcturus has developed proprietary lipid nanoparticle RNA therapeutics for nucleic acid medicines including small interfering...
    19 KB (1,787 words) - 16:02, 13 February 2024
  • DMG-PEG 2000 is a synthetic lipid formed by the PEGylation of myristoyl diglyceride. It is used to manufacture lipid nanoparticles that are used in mRNA vaccines...
    3 KB (118 words) - 07:41, 25 November 2023
  • Thumbnail for Amphotericin B
    lipid-based drug delivery systems including cochleates, self-emulsifying drug delivery systems, solid lipid nanoparticles and polymeric nanoparticles—such...
    43 KB (4,068 words) - 06:15, 1 April 2024
  • Thumbnail for Colloidal gold
    Colloidal gold is a sol or colloidal suspension of nanoparticles of gold in a fluid, usually water. The colloid is coloured usually either wine red (for...
    85 KB (9,809 words) - 02:25, 10 April 2024
  • Thumbnail for Silver nanoparticle
    Silver nanoparticles are nanoparticles of silver of between 1 nm and 100 nm in size. While frequently described as being 'silver' some are composed of...
    96 KB (12,133 words) - 13:19, 23 April 2024
  • Thumbnail for Drug delivery
    Verbeke, R; Kersten, G; Jiskoot, W; Crommelin, DJA (April 2021). "mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability". Int J Pharm. 601 (120586):...
    26 KB (2,849 words) - 08:20, 24 March 2024
  • Thumbnail for Patisiran
    is formulated into lipid nanoparticles, which protect the RNA and facilitate its delivery to target tissues. The lipid nanoparticle formulation includes...
    15 KB (952 words) - 06:33, 10 March 2024
  • Intellia's proprietary non-viral gene knock out platform deploys lipid nanoparticles to deliver to the liver a two-part genome editing system: guide RNA...
    18 KB (1,607 words) - 07:43, 23 February 2024
  • their hydrogenation results in 85% DSPC. It can be used to prepare lipid nanoparticles which are used in mRNA vaccines, In particular, it forms part of...
    3 KB (254 words) - 00:09, 4 December 2023
  • Thumbnail for Small interfering RNA
    different non-lipid based organic nanovectors such as cyclodextrin based nanoparticles. siRNAs delivered via lipid based nanoparticles have been shown...
    55 KB (6,760 words) - 18:46, 18 April 2024
  • Thumbnail for Platinum nanoparticle
    Platinum nanoparticles are usually in the form of a suspension or colloid of nanoparticles of platinum in a fluid, usually water. A colloid is technically...
    45 KB (5,344 words) - 03:43, 4 September 2023
  • lipid nanoparticles (LNP). Cullis and co-workers have been responsible for fundamental advances in the development of nanomedicines employing lipid nanoparticle...
    19 KB (1,222 words) - 22:00, 23 April 2024
  • Thumbnail for Lipid bilayer
    The lipid bilayer (or phospholipid bilayer) is a thin polar membrane made of two layers of lipid molecules. These membranes are flat sheets that form a...
    81 KB (9,777 words) - 03:22, 14 March 2024
  • ALC-0159 (category Lipids)
    Gideon; Jiskoot, Wim; Crommelin, Daan J. A. (2021-05-15). "mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability". International Journal...
    2 KB (205 words) - 21:16, 8 February 2024
  • Thumbnail for PEGylation
    combined immunodeficiency disease (SCID) (Enzon, 1990) The PEGylated lipid nanoparticle drug delivery (LNP) system of the mRNA vaccine known as mRNA-1273...
    27 KB (2,984 words) - 14:51, 21 February 2024
  • Thumbnail for N1-Methylpseudouridine
    Muramatsu H, Stotesbury C, Tang L, Lin PJ, et al. (September 2021). "Lipid-nanoparticle-encapsulated mRNA vaccines induce protective memory CD8 T cells against...
    16 KB (1,510 words) - 19:37, 11 April 2024
  • Thumbnail for Moderna COVID-19 vaccine
    encoding a spike protein of SARS-CoV-2, which is encapsulated in lipid nanoparticles. It is authorized for use at some level in many countries. In August...
    164 KB (12,843 words) - 21:05, 19 February 2024
  • lipoplexes, or micelles. These four major types of nanoparticles are all nonionic lipids. Nonionic lipids are safe, nontoxic and biocompatible. Nanoplexes...
    6 KB (727 words) - 01:29, 3 December 2023